Name	Flags	Card.	Type	Description & Constraints
MedicationRequest		0..*	MedicationRequest	Ordering of medication for patient or group dom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated dom-5: If a resource is contained in another resource, it SHALL NOT have a security label dom-6: A resource should have narrative for robust management
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created ele-1: All FHIR elements must have a @value or children
contained		0..*	Resource	Contained, inline Resources
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:oncofair-element-form	S	0..1	CodeableConcept	Pharmaceutical form of the prescription/administration item URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-element-form ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:oncofair-mr-element-supply	S	0..1	boolean	Specifies whether the prescription item must be supplied by the pharmacy or not URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-supply ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:oncofair-mr-element-rank	S	0..1	integer	Gives the rank of the prescription element in the prescription according to a total order of prescription elements on the prescription object to which they are attached. URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-rank ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:oncofair-mr-element-go-nogo	S	0..1	(Complex)	OncoFAIRMRElementGoNogo URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-go-nogo ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:oncofair-pharmacist-advice	S	0..1	(Complex)	OncoFAIRPharmacistAdvice URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-pharmacist-advice ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
identifier	S	1..1	Identifier	Unique identifier of the prescription item by the prescriber ele-1: All FHIR elements must have a @value or children
use	?!Σ	0..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known . ele-1: All FHIR elements must have a @value or children
value	ΣC	1..1	string	The value that is unique ele-1: All FHIR elements must have a @value or children Example General: 123456
Slices for basedOn	SΣ	1..*	Reference(CarePlan | MedicationRequest | ServiceRequest | ImmunizationRecommendation)	A plan or request that is fulfilled in whole or in part by this medication request Slice: Unordered, Open by profile:resolve() ele-1: All FHIR elements must have a @value or children
basedOn:prescription	Σ	1..1	Reference(OncoFAIR MedicationRequest Prescription)	The prescription linked to the element of prescription ele-1: All FHIR elements must have a @value or children
basedOn:element	Σ	0..*	Reference(OncoFAIR MedicationRequest Element)	The element linked to the element of prescription ele-1: All FHIR elements must have a @value or children
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:oncofair-mr-element-link-type		1..1	CodeableConcept	Type of link between the two prescription elements URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-link-type ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
reference	ΣC	0..1	string	Literal reference, Relative, internal or absolute URL ele-1: All FHIR elements must have a @value or children
basedOn:protocol	Σ	0..1	Reference(OncoFAIR CarePlan)	The protocol linked to the element of prescription ele-1: All FHIR elements must have a @value or children
groupIdentifier	SΣ	1..1	Identifier	Identifier common to all components of the same prescription ele-1: All FHIR elements must have a @value or children
use	?!Σ	0..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known . ele-1: All FHIR elements must have a @value or children
value	ΣC	1..1	string	The value that is unique ele-1: All FHIR elements must have a @value or children Example General: 123456
status	?!SΣ	1..1	code	Indicates the status of the protocol from the prescriber's point of view Binding: MedicationrequestStatus (required): A coded concept specifying the state of the prescribing event. Describes the lifecycle of the prescription. ele-1: All FHIR elements must have a @value or children
intent	?!Σ	1..1	code	proposal | plan | order | original-order | reflex-order | filler-order | instance-order | option Binding: MedicationRequestIntent (required): The kind of medication order. ele-1: All FHIR elements must have a @value or children
priority	SΣ	0..1	code	Attribute indicating the urgency with which the prescription item must be completed Binding: RequestPriority (required): Identifies the level of importance to be assigned to actioning the request. ele-1: All FHIR elements must have a @value or children
doNotPerform	?!Σ	0..1	boolean	True if patient is to stop taking or not to start taking the medication ele-1: All FHIR elements must have a @value or children
medication	SΣ	1..1	CodeableReference(Medication)	Medication to be taken Binding: Concepts Medication Value Set (required) ele-1: All FHIR elements must have a @value or children
concept	Σ	0..1	CodeableConcept	Reference to a concept (by class) ele-1: All FHIR elements must have a @value or children Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
code		1..1	code	Symbol in syntax defined by the system Fixed Value: element
subject	Σ	1..1	Reference(Patient | Group)	Individual or group for whom the medication has been requested ele-1: All FHIR elements must have a @value or children
requester	SΣ	0..1	Reference(Practitioner)	The requester linked to the element of prescription ele-1: All FHIR elements must have a @value or children
device	S	0..*	CodeableReference(DeviceDefinition)	Specifies, where applicable, the medical devices or equipment to be used to administer the product ele-1: All FHIR elements must have a @value or children
Slices for note	S	0..*	Annotation	Information about the prescription Slice: Unordered, Open by value:id ele-1: All FHIR elements must have a @value or children
note:wording		0..1	Annotation	Prescription element wording ele-1: All FHIR elements must have a @value or children
id		1..1	id	Unique id for inter-element referencing Required Pattern: wording
text	Σ	1..1	markdown	The annotation - text content (as markdown) ele-1: All FHIR elements must have a @value or children
note:indication		0..1	Annotation	Explain the reasons that led the prescriber to prescribe this item ele-1: All FHIR elements must have a @value or children
id		1..1	id	Unique id for inter-element referencing Required Pattern: indication
text	Σ	1..1	markdown	The annotation - text content (as markdown) ele-1: All FHIR elements must have a @value or children
note:comments		0..1	Annotation	Comments associated with this element, which represents the smallest entity that can be administered to the patient ele-1: All FHIR elements must have a @value or children
id		1..1	id	Unique id for inter-element referencing Required Pattern: comments
text	Σ	1..1	markdown	The annotation - text content (as markdown) ele-1: All FHIR elements must have a @value or children
effectiveDosePeriod	S	0..1	Period	Effective start and end date and time of product prescription ele-1: All FHIR elements must have a @value or children
start	ΣC	0..1	dateTime	Starting time with inclusive boundary ele-1: All FHIR elements must have a @value or children
end	ΣC	0..1	dateTime	End time with inclusive boundary, if not ongoing ele-1: All FHIR elements must have a @value or children
Slices for dosageInstruction	S	0..*	Dosage	Specific instructions for how the medication should be taken Slice: Unordered, Open by value:id ele-1: All FHIR elements must have a @value or children
dosageInstruction:element		0..1	Dosage	Specific instructions for how the medication should be taken ele-1: All FHIR elements must have a @value or children
id		1..1	id	Unique id for inter-element referencing Required Pattern: element
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
text	Σ	0..1	string	Description of the prescribed dosage, in text form. ele-1: All FHIR elements must have a @value or children
additionalInstruction	Σ	0..1	CodeableConcept	Free text describing the conditions of application of this prescription element Binding: SNOMEDCTAdditionalDosageInstructions (example): A coded concept identifying additional instructions such as "take with water" or "avoid operating heavy machinery". ele-1: All FHIR elements must have a @value or children
site	Σ	0..1	CodeableConcept	Specifies, where appropriate, the exact point on the body where the product is to be applied to the patient Binding: SNOMEDCTAnatomicalStructureAdministrationSites (example): A coded concept describing the site location the medicine enters into or onto the body. ele-1: All FHIR elements must have a @value or children
route	Σ	0..1	CodeableConcept	Specifies the route of administration of the product Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject. ele-1: All FHIR elements must have a @value or children
method	Σ	0..1	CodeableConcept	Type of prescription element Binding: Type de l'élément d'administration Value Set (required) ele-1: All FHIR elements must have a @value or children
dosageInstruction:posology		0..*	Dosage	Specific instructions for how the medication should be taken ele-1: All FHIR elements must have a @value or children
id		1..1	id	Unique id for inter-element referencing Required Pattern: posology
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
substitution	S	0..1	BackboneElement	Characterises a prescription item added by the pharmacist, either as a proposed replacement or as a suggestion ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
allowed[x]		1..1		Whether substitution is allowed or not Binding: ActSubstanceAdminSubstitutionCode (preferred): Identifies the type of substitution allowed. ele-1: All FHIR elements must have a @value or children
allowedBoolean			boolean
allowedCodeableConcept			CodeableConcept
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationRequest.identifier.use	required	IdentifierUse http://hl7.org/fhir/ValueSet/identifier-use|5.0.0 from the FHIR Standard
MedicationRequest.groupIdentifier.use	required	IdentifierUse http://hl7.org/fhir/ValueSet/identifier-use|5.0.0 from the FHIR Standard
MedicationRequest.status	required	MedicationrequestStatus http://hl7.org/fhir/ValueSet/medicationrequest-status|5.0.0 from the FHIR Standard
MedicationRequest.intent	required	MedicationRequestIntent http://hl7.org/fhir/ValueSet/medicationrequest-intent|5.0.0 from the FHIR Standard
MedicationRequest.priority	required	RequestPriority http://hl7.org/fhir/ValueSet/request-priority|5.0.0 from the FHIR Standard
MedicationRequest.medication	required	ConceptMedicationOncoFAIRValueSet (a valid code from Concepts Medication Code System) http://ltsi.univ-rennes.fr/ValueSet/concept-medication-oncofair-valueset from this IG
MedicationRequest.dosageInstruction:element.additionalInstruction	example	SNOMEDCTAdditionalDosageInstructions http://hl7.org/fhir/ValueSet/additional-instruction-codes from the FHIR Standard
MedicationRequest.dosageInstruction:element.site	example	SNOMEDCTAnatomicalStructureAdministrationSites http://hl7.org/fhir/ValueSet/approach-site-codes from the FHIR Standard
MedicationRequest.dosageInstruction:element.route	example	SNOMEDCTRouteCodes http://hl7.org/fhir/ValueSet/route-codes from the FHIR Standard
MedicationRequest.dosageInstruction:element.method	required	SIPhTypeEltPLAOncoFAIRValueSet (a valid code from Type de l'élément d'administration Code System) http://ltsi.univ-rennes.fr/ValueSet/siph-typeeltpla-oncofair-valueset from this IG
MedicationRequest.substitution.allowed[x]	preferred	ActSubstanceAdminSubstitutionCode http://terminology.hl7.org/ValueSet/v3-ActSubstanceAdminSubstitutionCode

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationRequest	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationRequest	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationRequest	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationRequest	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationRequest	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

Name	Flags	Card.	Type	Description & Constraints
MedicationRequest		0..*	MedicationRequest	Ordering of medication for patient or group
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:oncofair-element-form	S	0..1	CodeableConcept	Pharmaceutical form of the prescription/administration item URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-element-form
extension:oncofair-mr-element-supply	S	0..1	boolean	Specifies whether the prescription item must be supplied by the pharmacy or not URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-supply
extension:oncofair-mr-element-rank	S	0..1	integer	Gives the rank of the prescription element in the prescription according to a total order of prescription elements on the prescription object to which they are attached. URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-rank
extension:oncofair-mr-element-go-nogo	S	0..1	(Complex)	OncoFAIRMRElementGoNogo URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-go-nogo
extension:oncofair-pharmacist-advice	S	0..1	(Complex)	OncoFAIRPharmacistAdvice URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-pharmacist-advice
identifier	S	1..1	Identifier	Unique identifier of the prescription item by the prescriber
value		1..1	string	The value that is unique
Slices for basedOn	S	1..*	Reference(CarePlan | MedicationRequest | ServiceRequest | ImmunizationRecommendation)	A plan or request that is fulfilled in whole or in part by this medication request Slice: Unordered, Open by profile:resolve()
basedOn:prescription		1..1	Reference(OncoFAIR MedicationRequest Prescription)	The prescription linked to the element of prescription
basedOn:element		0..*	Reference(OncoFAIR MedicationRequest Element)	The element linked to the element of prescription
extension		1..*	Extension	Extension
Slices for extension				Content/Rules for all slices
extension:oncofair-mr-element-link-type		1..1	CodeableConcept	Type of link between the two prescription elements URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-link-type
basedOn:protocol		0..1	Reference(OncoFAIR CarePlan)	The protocol linked to the element of prescription
groupIdentifier	S	1..1	Identifier	Identifier common to all components of the same prescription
value		1..1	string	The value that is unique
status	S	1..1	code	Indicates the status of the protocol from the prescriber's point of view
priority	S	0..1	code	Attribute indicating the urgency with which the prescription item must be completed
medication	S	1..1	CodeableReference(Medication)	Medication to be taken Binding: Concepts Medication Value Set (required)
concept		0..1	CodeableConcept	Reference to a concept (by class) Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
code		1..1	code	Symbol in syntax defined by the system Fixed Value: element
requester	S	0..1	Reference(Practitioner)	The requester linked to the element of prescription
device	S	0..*	CodeableReference(DeviceDefinition)	Specifies, where applicable, the medical devices or equipment to be used to administer the product
Slices for note	S	0..*	Annotation	Information about the prescription Slice: Unordered, Open by value:id
note:wording		0..1	Annotation	Prescription element wording
id		1..1	id	Unique id for inter-element referencing Required Pattern: wording
note:indication		0..1	Annotation	Explain the reasons that led the prescriber to prescribe this item
id		1..1	id	Unique id for inter-element referencing Required Pattern: indication
note:comments		0..1	Annotation	Comments associated with this element, which represents the smallest entity that can be administered to the patient
id		1..1	id	Unique id for inter-element referencing Required Pattern: comments
effectiveDosePeriod	S	0..1	Period	Effective start and end date and time of product prescription
start		0..1	dateTime	Starting time with inclusive boundary
end		0..1	dateTime	End time with inclusive boundary, if not ongoing
Slices for dosageInstruction	S	0..*	Dosage	Specific instructions for how the medication should be taken Slice: Unordered, Open by value:id
dosageInstruction:element		0..1	Dosage	Specific instructions for how the medication should be taken
id		1..1	id	Unique id for inter-element referencing Required Pattern: element
text		0..1	string	Description of the prescribed dosage, in text form.
additionalInstruction		0..1	CodeableConcept	Free text describing the conditions of application of this prescription element
timing
repeat
Slices for bounds[x]		0..1	Duration, Range, Period	Length/Range of lengths, or (Start and/or end) limits Slice: Unordered, Open by type:$this
bounds[x]:boundsPeriod		0..1	Period	Length/Range of lengths, or (Start and/or end) limits
start		0..1	dateTime	Prescribed start date and time of product prescription
end		0..1	dateTime	Prescribed end date and time of product prescription
offset		0..1	unsignedInt	Decimal value, positive or negative, of the interval between the reference date/time of the prescribed protocol and that of this prescription item
site		0..1	CodeableConcept	Specifies, where appropriate, the exact point on the body where the product is to be applied to the patient
route		0..1	CodeableConcept	Specifies the route of administration of the product
method		0..1	CodeableConcept	Type of prescription element Binding: Type de l'élément d'administration Value Set (required)
dosageInstruction:posology		0..*	Dosage	Specific instructions for how the medication should be taken
id		1..1	id	Unique id for inter-element referencing Required Pattern: posology
timing
repeat
duration		0..1	decimal	Duration of administration
frequency		0..1	positiveInt	Indicates the recurrence of the dosage. By default, every day
doseAndRate
Slices for dose[x]		0..1	Range, SimpleQuantity	Amount of medication per dose Slice: Unordered, Open by type:$this
dose[x]:doseQuantity		0..1	SimpleQuantity	Quantity of the prescription element in the dosage
Slices for rate[x]		0..1	Ratio, Range, SimpleQuantity	Amount of medication per unit of time Slice: Unordered, Open by type:$this
rate[x]:rateQuantity		0..1	SimpleQuantity	Rate of administration in the case of injection
substitution	S	0..1	BackboneElement	Characterises a prescription item added by the pharmacist, either as a proposed replacement or as a suggestion
Documentation for this format

Terminology Bindings (Differential)

Path	Conformance	ValueSet	URI
MedicationRequest.medication	required	ConceptMedicationOncoFAIRValueSet (a valid code from Concepts Medication Code System) http://ltsi.univ-rennes.fr/ValueSet/concept-medication-oncofair-valueset from this IG
MedicationRequest.dosageInstruction:element.method	required	SIPhTypeEltPLAOncoFAIRValueSet (a valid code from Type de l'élément d'administration Code System) http://ltsi.univ-rennes.fr/ValueSet/siph-typeeltpla-oncofair-valueset from this IG

Name	Flags	Card.	Type	Description & Constraints
MedicationRequest		0..*	MedicationRequest	Ordering of medication for patient or group
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: AllLanguages (required): IETF language tag for a human language Additional Bindings Purpose CommonLanguages Starter
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:oncofair-element-form	S	0..1	CodeableConcept	Pharmaceutical form of the prescription/administration item URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-element-form
extension:oncofair-mr-element-supply	S	0..1	boolean	Specifies whether the prescription item must be supplied by the pharmacy or not URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-supply
extension:oncofair-mr-element-rank	S	0..1	integer	Gives the rank of the prescription element in the prescription according to a total order of prescription elements on the prescription object to which they are attached. URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-rank
extension:oncofair-mr-element-go-nogo	S	0..1	(Complex)	OncoFAIRMRElementGoNogo URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-go-nogo
extension:oncofair-pharmacist-advice	S	0..1	(Complex)	OncoFAIRPharmacistAdvice URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-pharmacist-advice
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored
identifier	S	1..1	Identifier	Unique identifier of the prescription item by the prescriber
id		0..1	id	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
use	?!Σ	0..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known .
type	Σ	0..1	CodeableConcept	Description of identifier Binding: IdentifierTypeCodes (extensible): A coded type for an identifier that can be used to determine which identifier to use for a specific purpose.
system	Σ	0..1	uri	The namespace for the identifier value Example General: http://www.acme.com/identifiers/patient
value	ΣC	1..1	string	The value that is unique Example General: 123456
period	Σ	0..1	Period	Time period when id is/was valid for use
assigner	Σ	0..1	Reference(Organization)	Organization that issued id (may be just text)
Slices for basedOn	SΣ	1..*	Reference(CarePlan | MedicationRequest | ServiceRequest | ImmunizationRecommendation)	A plan or request that is fulfilled in whole or in part by this medication request Slice: Unordered, Open by profile:resolve()
basedOn:prescription	Σ	1..1	Reference(OncoFAIR MedicationRequest Prescription)	The prescription linked to the element of prescription
basedOn:element	Σ	0..*	Reference(OncoFAIR MedicationRequest Element)	The element linked to the element of prescription
id		0..1	id	Unique id for inter-element referencing
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:oncofair-mr-element-link-type		1..1	CodeableConcept	Type of link between the two prescription elements URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-link-type
reference	ΣC	0..1	string	Literal reference, Relative, internal or absolute URL
type	Σ	0..1	uri	Type the reference refers to (e.g. "Patient") - must be a resource in resources Binding: ResourceType (extensible): Aa resource (or, for logical models, the URI of the logical model).
identifier	ΣC	0..1	Identifier	Logical reference, when literal reference is not known
display	ΣC	0..1	string	Text alternative for the resource
basedOn:protocol	Σ	0..1	Reference(OncoFAIR CarePlan)	The protocol linked to the element of prescription
priorPrescription		0..1	Reference(MedicationRequest)	Reference to an order/prescription that is being replaced by this MedicationRequest
groupIdentifier	SΣ	1..1	Identifier	Identifier common to all components of the same prescription
id		0..1	id	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
use	?!Σ	0..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known .
type	Σ	0..1	CodeableConcept	Description of identifier Binding: IdentifierTypeCodes (extensible): A coded type for an identifier that can be used to determine which identifier to use for a specific purpose.
system	Σ	0..1	uri	The namespace for the identifier value Example General: http://www.acme.com/identifiers/patient
value	ΣC	1..1	string	The value that is unique Example General: 123456
period	Σ	0..1	Period	Time period when id is/was valid for use
assigner	Σ	0..1	Reference(Organization)	Organization that issued id (may be just text)
status	?!SΣ	1..1	code	Indicates the status of the protocol from the prescriber's point of view Binding: MedicationrequestStatus (required): A coded concept specifying the state of the prescribing event. Describes the lifecycle of the prescription.
statusReason		0..1	CodeableConcept	Reason for current status Binding: MedicationRequestStatusReasonCodes (example): Identifies the reasons for a given status.
statusChanged		0..1	dateTime	When the status was changed
intent	?!Σ	1..1	code	proposal | plan | order | original-order | reflex-order | filler-order | instance-order | option Binding: MedicationRequestIntent (required): The kind of medication order.
category		0..*	CodeableConcept	Grouping or category of medication request Binding: MedicationRequestAdministrationLocationCodes (example): A coded concept identifying where the medication is to be consumed or administered.
priority	SΣ	0..1	code	Attribute indicating the urgency with which the prescription item must be completed Binding: RequestPriority (required): Identifies the level of importance to be assigned to actioning the request.
doNotPerform	?!Σ	0..1	boolean	True if patient is to stop taking or not to start taking the medication
medication	SΣ	1..1	CodeableReference(Medication)	Medication to be taken Binding: Concepts Medication Value Set (required)
id		0..1	id	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
concept	Σ	0..1	CodeableConcept	Reference to a concept (by class) Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		0..1	uri	Identity of the terminology system
version		0..1	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: element
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text		0..1	string	Plain text representation of the concept
reference	Σ	0..1	Reference()	Reference to a resource (by instance)
subject	Σ	1..1	Reference(Patient | Group)	Individual or group for whom the medication has been requested
informationSource		0..*	Reference(Patient | Practitioner | PractitionerRole | RelatedPerson | Organization)	The person or organization who provided the information about this request, if the source is someone other than the requestor
encounter		0..1	Reference(Encounter)	Encounter created as part of encounter/admission/stay
supportingInformation		0..*	Reference(Resource)	Information to support fulfilling of the medication
authoredOn	Σ	0..1	dateTime	When request was initially authored
requester	SΣ	0..1	Reference(Practitioner)	The requester linked to the element of prescription
reported	Σ	0..1	boolean	Reported rather than primary record
performerType	Σ	0..1	CodeableConcept	Desired kind of performer of the medication administration Binding: MedicationIntendedPerformerRole (extensible): Identifies the type of individual that is desired to administer the medication.
performer		0..*	Reference(Practitioner | PractitionerRole | Organization | Patient | DeviceDefinition | RelatedPerson | CareTeam | HealthcareService)	Intended performer of administration
device	S	0..*	CodeableReference(DeviceDefinition)	Specifies, where applicable, the medical devices or equipment to be used to administer the product
recorder		0..1	Reference(Practitioner | PractitionerRole)	Person who entered the request
reason		0..*	CodeableReference(Condition | Observation)	Reason or indication for ordering or not ordering the medication Binding: ConditionProblemDiagnosisCodes (example): A coded concept indicating why the medication was ordered.
courseOfTherapyType		0..1	CodeableConcept	Overall pattern of medication administration Binding: MedicationRequestCourseOfTherapyCodes (extensible): Identifies the overall pattern of medication administratio.
insurance		0..*	Reference(Coverage | ClaimResponse)	Associated insurance coverage
Slices for note	S	0..*	Annotation	Information about the prescription Slice: Unordered, Open by value:id
note:wording		0..1	Annotation	Prescription element wording
id		1..1	id	Unique id for inter-element referencing Required Pattern: wording
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
author[x]	Σ	0..1		Individual responsible for the annotation
authorReference			Reference(Practitioner | PractitionerRole | Patient | RelatedPerson | Organization)
authorString			string
time	Σ	0..1	dateTime	When the annotation was made
text	Σ	1..1	markdown	The annotation - text content (as markdown)
note:indication		0..1	Annotation	Explain the reasons that led the prescriber to prescribe this item
id		1..1	id	Unique id for inter-element referencing Required Pattern: indication
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
author[x]	Σ	0..1		Individual responsible for the annotation
authorReference			Reference(Practitioner | PractitionerRole | Patient | RelatedPerson | Organization)
authorString			string
time	Σ	0..1	dateTime	When the annotation was made
text	Σ	1..1	markdown	The annotation - text content (as markdown)
note:comments		0..1	Annotation	Comments associated with this element, which represents the smallest entity that can be administered to the patient
id		1..1	id	Unique id for inter-element referencing Required Pattern: comments
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
author[x]	Σ	0..1		Individual responsible for the annotation
authorReference			Reference(Practitioner | PractitionerRole | Patient | RelatedPerson | Organization)
authorString			string
time	Σ	0..1	dateTime	When the annotation was made
text	Σ	1..1	markdown	The annotation - text content (as markdown)
renderedDosageInstruction		0..1	markdown	Full representation of the dosage instructions
effectiveDosePeriod	S	0..1	Period	Effective start and end date and time of product prescription
id		0..1	id	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
start	ΣC	0..1	dateTime	Starting time with inclusive boundary
end	ΣC	0..1	dateTime	End time with inclusive boundary, if not ongoing
Slices for dosageInstruction	S	0..*	Dosage	Specific instructions for how the medication should be taken Slice: Unordered, Open by value:id
dosageInstruction:element		0..1	Dosage	Specific instructions for how the medication should be taken
id		1..1	id	Unique id for inter-element referencing Required Pattern: element
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequence	Σ	0..1	integer	The order of the dosage instructions
text	Σ	0..1	string	Description of the prescribed dosage, in text form.
additionalInstruction	Σ	0..1	CodeableConcept	Free text describing the conditions of application of this prescription element Binding: SNOMEDCTAdditionalDosageInstructions (example): A coded concept identifying additional instructions such as "take with water" or "avoid operating heavy machinery".
patientInstruction	Σ	0..1	string	Patient or consumer oriented instructions
timing	Σ	0..1	Timing	When medication should be administered
id		0..1	id	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
event	Σ	0..*	dateTime	When the event occurs
repeat	ΣC	0..1	Element	When the event is to occur tim-1: if there's a duration, there needs to be duration units tim-2: if there's a period, there needs to be period units tim-4: duration SHALL be a non-negative value tim-5: period SHALL be a non-negative value tim-6: If there's a periodMax, there must be a period tim-7: If there's a durationMax, there must be a duration tim-8: If there's a countMax, there must be a count tim-9: If there's an offset, there must be a when (and not C, CM, CD, CV) tim-10: If there's a timeOfDay, there cannot be a when, or vice versa
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
Slices for bounds[x]	Σ	0..1		Length/Range of lengths, or (Start and/or end) limits Slice: Unordered, Open by type:$this
boundsDuration			Duration
boundsRange			Range
boundsPeriod			Period
bounds[x]:boundsPeriod	Σ	0..1	Period	Length/Range of lengths, or (Start and/or end) limits
id		0..1	id	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
start	ΣC	0..1	dateTime	Prescribed start date and time of product prescription
end	ΣC	0..1	dateTime	Prescribed end date and time of product prescription
count	ΣC	0..1	positiveInt	Number of times to repeat
countMax	ΣC	0..1	positiveInt	Maximum number of times to repeat
duration	ΣC	0..1	decimal	How long when it happens
durationMax	ΣC	0..1	decimal	How long when it happens (Max)
durationUnit	ΣC	0..1	code	s | min | h | d | wk | mo | a - unit of time (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
frequency	Σ	0..1	positiveInt	Indicates the number of repetitions that should occur within a period. I.e. Event occurs frequency times per period
frequencyMax	Σ	0..1	positiveInt	Event occurs up to frequencyMax times per period
period	ΣC	0..1	decimal	The duration to which the frequency applies. I.e. Event occurs frequency times per period
periodMax	ΣC	0..1	decimal	Upper limit of period (3-4 hours)
periodUnit	ΣC	0..1	code	s | min | h | d | wk | mo | a - unit of time (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
dayOfWeek	Σ	0..*	code	mon | tue | wed | thu | fri | sat | sun Binding: DaysOfWeek (required)
timeOfDay	ΣC	0..*	time	Time of day for action
when	ΣC	0..*	code	Code for time period of occurrence Binding: EventTiming (required): Real-world event relating to the schedule.
offset	ΣC	0..1	unsignedInt	Decimal value, positive or negative, of the interval between the reference date/time of the prescribed protocol and that of this prescription item
code	Σ	0..1	CodeableConcept	C | BID | TID | QID | AM | PM | QD | QOD | + Binding: TimingAbbreviation (preferred): Code for a known / defined timing pattern.
asNeeded	ΣC	0..1	boolean	Take "as needed"
asNeededFor	ΣC	0..*	CodeableConcept	Take "as needed" (for x) Binding: SNOMEDCTMedicationAsNeededReasonCodes (example): A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc.
site	Σ	0..1	CodeableConcept	Specifies, where appropriate, the exact point on the body where the product is to be applied to the patient Binding: SNOMEDCTAnatomicalStructureAdministrationSites (example): A coded concept describing the site location the medicine enters into or onto the body.
route	Σ	0..1	CodeableConcept	Specifies the route of administration of the product Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.
method	Σ	0..1	CodeableConcept	Type of prescription element Binding: Type de l'élément d'administration Value Set (required)
doseAndRate	Σ	0..*	Element	Amount of medication administered, to be administered or typical amount to be administered
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
type	Σ	0..1	CodeableConcept	The kind of dose or rate specified Binding: DoseAndRateType (example): The kind of dose or rate specified.
dose[x]	Σ	0..1		Amount of medication per dose
doseRange			Range
doseQuantity			Quantity(SimpleQuantity)
rate[x]	Σ	0..1		Amount of medication per unit of time
rateRatio			Ratio
rateRange			Range
rateQuantity			Quantity(SimpleQuantity)
maxDosePerPeriod	Σ	0..*	Ratio	Upper limit on medication per unit of time
maxDosePerAdministration	Σ	0..1	SimpleQuantity	Upper limit on medication per administration
maxDosePerLifetime	Σ	0..1	SimpleQuantity	Upper limit on medication per lifetime of the patient
dosageInstruction:posology		0..*	Dosage	Specific instructions for how the medication should be taken
id		1..1	id	Unique id for inter-element referencing Required Pattern: posology
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequence	Σ	0..1	integer	The order of the dosage instructions
text	Σ	0..1	string	Free text dosage instructions e.g. SIG
additionalInstruction	Σ	0..*	CodeableConcept	Supplemental instruction or warnings to the patient - e.g. "with meals", "may cause drowsiness" Binding: SNOMEDCTAdditionalDosageInstructions (example): A coded concept identifying additional instructions such as "take with water" or "avoid operating heavy machinery".
patientInstruction	Σ	0..1	string	Patient or consumer oriented instructions
timing	Σ	0..1	Timing	When medication should be administered
id		0..1	id	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
event	Σ	0..*	dateTime	When the event occurs
repeat	ΣC	0..1	Element	When the event is to occur tim-1: if there's a duration, there needs to be duration units tim-2: if there's a period, there needs to be period units tim-4: duration SHALL be a non-negative value tim-5: period SHALL be a non-negative value tim-6: If there's a periodMax, there must be a period tim-7: If there's a durationMax, there must be a duration tim-8: If there's a countMax, there must be a count tim-9: If there's an offset, there must be a when (and not C, CM, CD, CV) tim-10: If there's a timeOfDay, there cannot be a when, or vice versa
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
bounds[x]	Σ	0..1		Length/Range of lengths, or (Start and/or end) limits
boundsDuration			Duration
boundsRange			Range
boundsPeriod			Period
count	ΣC	0..1	positiveInt	Number of times to repeat
countMax	ΣC	0..1	positiveInt	Maximum number of times to repeat
duration	ΣC	0..1	decimal	Duration of administration
durationMax	ΣC	0..1	decimal	How long when it happens (Max)
durationUnit	ΣC	0..1	code	s | min | h | d | wk | mo | a - unit of time (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
frequency	Σ	0..1	positiveInt	Indicates the recurrence of the dosage. By default, every day
frequencyMax	Σ	0..1	positiveInt	Event occurs up to frequencyMax times per period
period	ΣC	0..1	decimal	The duration to which the frequency applies. I.e. Event occurs frequency times per period
periodMax	ΣC	0..1	decimal	Upper limit of period (3-4 hours)
periodUnit	ΣC	0..1	code	s | min | h | d | wk | mo | a - unit of time (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
dayOfWeek	Σ	0..*	code	mon | tue | wed | thu | fri | sat | sun Binding: DaysOfWeek (required)
timeOfDay	ΣC	0..*	time	Time of day for action
when	ΣC	0..*	code	Code for time period of occurrence Binding: EventTiming (required): Real-world event relating to the schedule.
offset	ΣC	0..1	unsignedInt	Minutes from event (before or after)
code	Σ	0..1	CodeableConcept	C | BID | TID | QID | AM | PM | QD | QOD | + Binding: TimingAbbreviation (preferred): Code for a known / defined timing pattern.
asNeeded	ΣC	0..1	boolean	Take "as needed"
asNeededFor	ΣC	0..*	CodeableConcept	Take "as needed" (for x) Binding: SNOMEDCTMedicationAsNeededReasonCodes (example): A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc.
site	Σ	0..1	CodeableConcept	Body site to administer to Binding: SNOMEDCTAnatomicalStructureAdministrationSites (example): A coded concept describing the site location the medicine enters into or onto the body.
route	Σ	0..1	CodeableConcept	How drug should enter body Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.
method	Σ	0..1	CodeableConcept	Technique for administering medication Binding: SNOMEDCTAdministrationMethodCodes (example): A coded concept describing the technique by which the medicine is administered.
doseAndRate	Σ	0..*	Element	Amount of medication administered, to be administered or typical amount to be administered
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
type	Σ	0..1	CodeableConcept	The kind of dose or rate specified Binding: DoseAndRateType (example): The kind of dose or rate specified.
Slices for dose[x]	Σ	0..1		Amount of medication per dose Slice: Unordered, Open by type:$this
doseRange			Range
doseQuantity			Quantity(SimpleQuantity)
dose[x]:doseQuantity	Σ	0..1	SimpleQuantity	Quantity of the prescription element in the dosage
Slices for rate[x]	Σ	0..1		Amount of medication per unit of time Slice: Unordered, Open by type:$this
rateRatio			Ratio
rateRange			Range
rateQuantity			Quantity(SimpleQuantity)
rate[x]:rateQuantity	Σ	0..1	SimpleQuantity	Rate of administration in the case of injection
maxDosePerPeriod	Σ	0..*	Ratio	Upper limit on medication per unit of time
maxDosePerAdministration	Σ	0..1	SimpleQuantity	Upper limit on medication per administration
maxDosePerLifetime	Σ	0..1	SimpleQuantity	Upper limit on medication per lifetime of the patient
dispenseRequest		0..1	BackboneElement	Medication supply authorization
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
initialFill		0..1	BackboneElement	First fill details
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
quantity		0..1	SimpleQuantity	First fill quantity
duration		0..1	Duration	First fill duration
dispenseInterval		0..1	Duration	Minimum period of time between dispenses
validityPeriod		0..1	Period	Time period supply is authorized for
numberOfRepeatsAllowed		0..1	unsignedInt	Number of refills authorized
quantity		0..1	SimpleQuantity	Amount of medication to supply per dispense
expectedSupplyDuration		0..1	Duration	Number of days supply per dispense
dispenser		0..1	Reference(Organization)	Intended performer of dispense
dispenserInstruction		0..*	Annotation	Additional information for the dispenser
doseAdministrationAid		0..1	CodeableConcept	Type of adherence packaging to use for the dispense Binding: MedicationDoseAids (example)
substitution	S	0..1	BackboneElement	Characterises a prescription item added by the pharmacist, either as a proposed replacement or as a suggestion
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
allowed[x]		1..1		Whether substitution is allowed or not Binding: ActSubstanceAdminSubstitutionCode (preferred): Identifies the type of substitution allowed.
allowedBoolean			boolean
allowedCodeableConcept			CodeableConcept
reason		0..1	CodeableConcept	Why should (not) substitution be made Binding: SubstanceAdminSubstitutionReason (example): SubstanceAdminSubstitutionReason
eventHistory		0..*	Reference(Provenance)	A list of events of interest in the lifecycle
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationRequest.language	required	AllLanguages http://hl7.org/fhir/ValueSet/all-languages|5.0.0 from the FHIR Standard
MedicationRequest.identifier.use	required	IdentifierUse http://hl7.org/fhir/ValueSet/identifier-use|5.0.0 from the FHIR Standard
MedicationRequest.identifier.type	extensible	IdentifierTypeCodes http://hl7.org/fhir/ValueSet/identifier-type from the FHIR Standard
MedicationRequest.basedOn:element.type	extensible	ResourceType http://hl7.org/fhir/ValueSet/resource-types from the FHIR Standard
MedicationRequest.groupIdentifier.use	required	IdentifierUse http://hl7.org/fhir/ValueSet/identifier-use|5.0.0 from the FHIR Standard
MedicationRequest.groupIdentifier.type	extensible	IdentifierTypeCodes http://hl7.org/fhir/ValueSet/identifier-type from the FHIR Standard
MedicationRequest.status	required	MedicationrequestStatus http://hl7.org/fhir/ValueSet/medicationrequest-status|5.0.0 from the FHIR Standard
MedicationRequest.statusReason	example	MedicationRequestStatusReasonCodes http://hl7.org/fhir/ValueSet/medicationrequest-status-reason from the FHIR Standard
MedicationRequest.intent	required	MedicationRequestIntent http://hl7.org/fhir/ValueSet/medicationrequest-intent|5.0.0 from the FHIR Standard
MedicationRequest.category	example	MedicationRequestAdministrationLocationCodes http://hl7.org/fhir/ValueSet/medicationrequest-admin-location from the FHIR Standard
MedicationRequest.priority	required	RequestPriority http://hl7.org/fhir/ValueSet/request-priority|5.0.0 from the FHIR Standard
MedicationRequest.medication	required	ConceptMedicationOncoFAIRValueSet (a valid code from Concepts Medication Code System) http://ltsi.univ-rennes.fr/ValueSet/concept-medication-oncofair-valueset from this IG
MedicationRequest.performerType	extensible	MedicationIntendedPerformerRole http://hl7.org/fhir/ValueSet/medication-intended-performer-role from the FHIR Standard
MedicationRequest.reason	example	ConditionProblemDiagnosisCodes http://hl7.org/fhir/ValueSet/condition-code from the FHIR Standard
MedicationRequest.courseOfTherapyType	extensible	MedicationRequestCourseOfTherapyCodes http://hl7.org/fhir/ValueSet/medicationrequest-course-of-therapy from the FHIR Standard
MedicationRequest.dosageInstruction:element.additionalInstruction	example	SNOMEDCTAdditionalDosageInstructions http://hl7.org/fhir/ValueSet/additional-instruction-codes from the FHIR Standard
MedicationRequest.dosageInstruction:element.timing.repeat.durationUnit	required	UnitsOfTime http://hl7.org/fhir/ValueSet/units-of-time|5.0.0 from the FHIR Standard
MedicationRequest.dosageInstruction:element.timing.repeat.periodUnit	required	UnitsOfTime http://hl7.org/fhir/ValueSet/units-of-time|5.0.0 from the FHIR Standard
MedicationRequest.dosageInstruction:element.timing.repeat.dayOfWeek	required	DaysOfWeek http://hl7.org/fhir/ValueSet/days-of-week|5.0.0 from the FHIR Standard
MedicationRequest.dosageInstruction:element.timing.repeat.when	required	EventTiming http://hl7.org/fhir/ValueSet/event-timing|5.0.0 from the FHIR Standard
MedicationRequest.dosageInstruction:element.timing.code	preferred	TimingAbbreviation http://hl7.org/fhir/ValueSet/timing-abbreviation from the FHIR Standard
MedicationRequest.dosageInstruction:element.asNeededFor	example	SNOMEDCTMedicationAsNeededReasonCodes http://hl7.org/fhir/ValueSet/medication-as-needed-reason from the FHIR Standard
MedicationRequest.dosageInstruction:element.site	example	SNOMEDCTAnatomicalStructureAdministrationSites http://hl7.org/fhir/ValueSet/approach-site-codes from the FHIR Standard
MedicationRequest.dosageInstruction:element.route	example	SNOMEDCTRouteCodes http://hl7.org/fhir/ValueSet/route-codes from the FHIR Standard
MedicationRequest.dosageInstruction:element.method	required	SIPhTypeEltPLAOncoFAIRValueSet (a valid code from Type de l'élément d'administration Code System) http://ltsi.univ-rennes.fr/ValueSet/siph-typeeltpla-oncofair-valueset from this IG
MedicationRequest.dosageInstruction:element.doseAndRate.type	example	DoseAndRateType http://terminology.hl7.org/ValueSet/dose-rate-type
MedicationRequest.dosageInstruction:posology.additionalInstruction	example	SNOMEDCTAdditionalDosageInstructions http://hl7.org/fhir/ValueSet/additional-instruction-codes from the FHIR Standard
MedicationRequest.dosageInstruction:posology.timing.repeat.durationUnit	required	UnitsOfTime http://hl7.org/fhir/ValueSet/units-of-time|5.0.0 from the FHIR Standard
MedicationRequest.dosageInstruction:posology.timing.repeat.periodUnit	required	UnitsOfTime http://hl7.org/fhir/ValueSet/units-of-time|5.0.0 from the FHIR Standard
MedicationRequest.dosageInstruction:posology.timing.repeat.dayOfWeek	required	DaysOfWeek http://hl7.org/fhir/ValueSet/days-of-week|5.0.0 from the FHIR Standard
MedicationRequest.dosageInstruction:posology.timing.repeat.when	required	EventTiming http://hl7.org/fhir/ValueSet/event-timing|5.0.0 from the FHIR Standard
MedicationRequest.dosageInstruction:posology.timing.code	preferred	TimingAbbreviation http://hl7.org/fhir/ValueSet/timing-abbreviation from the FHIR Standard
MedicationRequest.dosageInstruction:posology.asNeededFor	example	SNOMEDCTMedicationAsNeededReasonCodes http://hl7.org/fhir/ValueSet/medication-as-needed-reason from the FHIR Standard
MedicationRequest.dosageInstruction:posology.site	example	SNOMEDCTAnatomicalStructureAdministrationSites http://hl7.org/fhir/ValueSet/approach-site-codes from the FHIR Standard
MedicationRequest.dosageInstruction:posology.route	example	SNOMEDCTRouteCodes http://hl7.org/fhir/ValueSet/route-codes from the FHIR Standard
MedicationRequest.dosageInstruction:posology.method	example	SNOMEDCTAdministrationMethodCodes http://hl7.org/fhir/ValueSet/administration-method-codes from the FHIR Standard
MedicationRequest.dosageInstruction:posology.doseAndRate.type	example	DoseAndRateType http://terminology.hl7.org/ValueSet/dose-rate-type
MedicationRequest.dispenseRequest.doseAdministrationAid	example	MedicationDoseAids http://hl7.org/fhir/ValueSet/medication-dose-aid from the FHIR Standard
MedicationRequest.substitution.allowed[x]	preferred	ActSubstanceAdminSubstitutionCode http://terminology.hl7.org/ValueSet/v3-ActSubstanceAdminSubstitutionCode
MedicationRequest.substitution.reason	example	SubstanceAdminSubstitutionReason http://terminology.hl7.org/ValueSet/v3-SubstanceAdminSubstitutionReason

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationRequest	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationRequest	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationRequest	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationRequest	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationRequest	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()
tim-1	error	MedicationRequest.dosageInstruction:element.timing.repeat, MedicationRequest.dosageInstruction:posology.timing.repeat	if there's a duration, there needs to be duration units : duration.empty() or durationUnit.exists()
tim-2	error	MedicationRequest.dosageInstruction:element.timing.repeat, MedicationRequest.dosageInstruction:posology.timing.repeat	if there's a period, there needs to be period units : period.empty() or periodUnit.exists()
tim-4	error	MedicationRequest.dosageInstruction:element.timing.repeat, MedicationRequest.dosageInstruction:posology.timing.repeat	duration SHALL be a non-negative value : duration.exists() implies duration >= 0
tim-5	error	MedicationRequest.dosageInstruction:element.timing.repeat, MedicationRequest.dosageInstruction:posology.timing.repeat	period SHALL be a non-negative value : period.exists() implies period >= 0
tim-6	error	MedicationRequest.dosageInstruction:element.timing.repeat, MedicationRequest.dosageInstruction:posology.timing.repeat	If there's a periodMax, there must be a period : periodMax.empty() or period.exists()
tim-7	error	MedicationRequest.dosageInstruction:element.timing.repeat, MedicationRequest.dosageInstruction:posology.timing.repeat	If there's a durationMax, there must be a duration : durationMax.empty() or duration.exists()
tim-8	error	MedicationRequest.dosageInstruction:element.timing.repeat, MedicationRequest.dosageInstruction:posology.timing.repeat	If there's a countMax, there must be a count : countMax.empty() or count.exists()
tim-9	error	MedicationRequest.dosageInstruction:element.timing.repeat, MedicationRequest.dosageInstruction:posology.timing.repeat	If there's an offset, there must be a when (and not C, CM, CD, CV) : offset.empty() or (when.exists() and when.select($this in ('C' | 'CM' | 'CD' | 'CV')).allFalse())
tim-10	error	MedicationRequest.dosageInstruction:element.timing.repeat, MedicationRequest.dosageInstruction:posology.timing.repeat	If there's a timeOfDay, there cannot be a when, or vice versa : timeOfDay.empty() or when.empty()

Summary

Mandatory: 6 elements(7 nested mandatory elements)
Must-Support: 17 elements

Structures

This structure refers to these other structures:

• OncoFAIR MedicationRequest Prescription (http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-medicationrequest-prescription)
• OncoFAIR MedicationRequest Element (http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-medicationrequest-element)
• OncoFAIR CarePlan (http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-careplan)
• SimpleQuantity (http://hl7.org/fhir/StructureDefinition/SimpleQuantity)

Extensions

This structure refers to these extensions:

• http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-element-form
• http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-supply
• http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-rank
• http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-go-nogo
• http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-pharmacist-advice
• http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-link-type

Slices

This structure defines the following Slices:

• The element 1 is sliced based on the value of MedicationRequest.basedOn
• The element 1 is sliced based on the value of MedicationRequest.note
• The element 1 is sliced based on the value of MedicationRequest.dosageInstruction
• The element 1 is sliced based on the value of MedicationRequest.dosageInstruction.timing.repeat.bounds[x]
• The element 1 is sliced based on the value of MedicationRequest.dosageInstruction.doseAndRate.dose[x]
• The element 1 is sliced based on the value of MedicationRequest.dosageInstruction.doseAndRate.rate[x]

Name	Flags	Card.	Type	Description & Constraints
MedicationRequest		0..*	MedicationRequest	Ordering of medication for patient or group dom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated dom-5: If a resource is contained in another resource, it SHALL NOT have a security label dom-6: A resource should have narrative for robust management
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created ele-1: All FHIR elements must have a @value or children
contained		0..*	Resource	Contained, inline Resources
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:oncofair-element-form	S	0..1	CodeableConcept	Pharmaceutical form of the prescription/administration item URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-element-form ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:oncofair-mr-element-supply	S	0..1	boolean	Specifies whether the prescription item must be supplied by the pharmacy or not URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-supply ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:oncofair-mr-element-rank	S	0..1	integer	Gives the rank of the prescription element in the prescription according to a total order of prescription elements on the prescription object to which they are attached. URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-rank ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:oncofair-mr-element-go-nogo	S	0..1	(Complex)	OncoFAIRMRElementGoNogo URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-go-nogo ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:oncofair-pharmacist-advice	S	0..1	(Complex)	OncoFAIRPharmacistAdvice URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-pharmacist-advice ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
identifier	S	1..1	Identifier	Unique identifier of the prescription item by the prescriber ele-1: All FHIR elements must have a @value or children
use	?!Σ	0..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known . ele-1: All FHIR elements must have a @value or children
value	ΣC	1..1	string	The value that is unique ele-1: All FHIR elements must have a @value or children Example General: 123456
Slices for basedOn	SΣ	1..*	Reference(CarePlan | MedicationRequest | ServiceRequest | ImmunizationRecommendation)	A plan or request that is fulfilled in whole or in part by this medication request Slice: Unordered, Open by profile:resolve() ele-1: All FHIR elements must have a @value or children
basedOn:prescription	Σ	1..1	Reference(OncoFAIR MedicationRequest Prescription)	The prescription linked to the element of prescription ele-1: All FHIR elements must have a @value or children
basedOn:element	Σ	0..*	Reference(OncoFAIR MedicationRequest Element)	The element linked to the element of prescription ele-1: All FHIR elements must have a @value or children
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:oncofair-mr-element-link-type		1..1	CodeableConcept	Type of link between the two prescription elements URL: http://ltsi.univ-rennes.fr/StructureDefinition/oncofair-mr-element-link-type ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
reference	ΣC	0..1	string	Literal reference, Relative, internal or absolute URL ele-1: All FHIR elements must have a @value or children
basedOn:protocol	Σ	0..1	Reference(OncoFAIR CarePlan)	The protocol linked to the element of prescription ele-1: All FHIR elements must have a @value or children
groupIdentifier	SΣ	1..1	Identifier	Identifier common to all components of the same prescription ele-1: All FHIR elements must have a @value or children
use	?!Σ	0..1	code	usual | official | temp | secondary | old (If known) Binding: IdentifierUse (required): Identifies the purpose for this identifier, if known . ele-1: All FHIR elements must have a @value or children
value	ΣC	1..1	string	The value that is unique ele-1: All FHIR elements must have a @value or children Example General: 123456
status	?!SΣ	1..1	code	Indicates the status of the protocol from the prescriber's point of view Binding: MedicationrequestStatus (required): A coded concept specifying the state of the prescribing event. Describes the lifecycle of the prescription. ele-1: All FHIR elements must have a @value or children
intent	?!Σ	1..1	code	proposal | plan | order | original-order | reflex-order | filler-order | instance-order | option Binding: MedicationRequestIntent (required): The kind of medication order. ele-1: All FHIR elements must have a @value or children
priority	SΣ	0..1	code	Attribute indicating the urgency with which the prescription item must be completed Binding: RequestPriority (required): Identifies the level of importance to be assigned to actioning the request. ele-1: All FHIR elements must have a @value or children
doNotPerform	?!Σ	0..1	boolean	True if patient is to stop taking or not to start taking the medication ele-1: All FHIR elements must have a @value or children
medication	SΣ	1..1	CodeableReference(Medication)	Medication to be taken Binding: Concepts Medication Value Set (required) ele-1: All FHIR elements must have a @value or children
concept	Σ	0..1	CodeableConcept	Reference to a concept (by class) ele-1: All FHIR elements must have a @value or children Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
code		1..1	code	Symbol in syntax defined by the system Fixed Value: element
subject	Σ	1..1	Reference(Patient | Group)	Individual or group for whom the medication has been requested ele-1: All FHIR elements must have a @value or children
requester	SΣ	0..1	Reference(Practitioner)	The requester linked to the element of prescription ele-1: All FHIR elements must have a @value or children
device	S	0..*	CodeableReference(DeviceDefinition)	Specifies, where applicable, the medical devices or equipment to be used to administer the product ele-1: All FHIR elements must have a @value or children
Slices for note	S	0..*	Annotation	Information about the prescription Slice: Unordered, Open by value:id ele-1: All FHIR elements must have a @value or children
note:wording		0..1	Annotation	Prescription element wording ele-1: All FHIR elements must have a @value or children
id		1..1	id	Unique id for inter-element referencing Required Pattern: wording
text	Σ	1..1	markdown	The annotation - text content (as markdown) ele-1: All FHIR elements must have a @value or children
note:indication		0..1	Annotation	Explain the reasons that led the prescriber to prescribe this item ele-1: All FHIR elements must have a @value or children
id		1..1	id	Unique id for inter-element referencing Required Pattern: indication
text	Σ	1..1	markdown	The annotation - text content (as markdown) ele-1: All FHIR elements must have a @value or children
note:comments		0..1	Annotation	Comments associated with this element, which represents the smallest entity that can be administered to the patient ele-1: All FHIR elements must have a @value or children
id		1..1	id	Unique id for inter-element referencing Required Pattern: comments
text	Σ	1..1	markdown	The annotation - text content (as markdown) ele-1: All FHIR elements must have a @value or children
effectiveDosePeriod	S	0..1	Period	Effective start and end date and time of product prescription ele-1: All FHIR elements must have a @value or children
start	ΣC	0..1	dateTime	Starting time with inclusive boundary ele-1: All FHIR elements must have a @value or children
end	ΣC	0..1	dateTime	End time with inclusive boundary, if not ongoing ele-1: All FHIR elements must have a @value or children
Slices for dosageInstruction	S	0..*	Dosage	Specific instructions for how the medication should be taken Slice: Unordered, Open by value:id ele-1: All FHIR elements must have a @value or children
dosageInstruction:element		0..1	Dosage	Specific instructions for how the medication should be taken ele-1: All FHIR elements must have a @value or children
id		1..1	id	Unique id for inter-element referencing Required Pattern: element
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
text	Σ	0..1	string	Description of the prescribed dosage, in text form. ele-1: All FHIR elements must have a @value or children
additionalInstruction	Σ	0..1	CodeableConcept	Free text describing the conditions of application of this prescription element Binding: SNOMEDCTAdditionalDosageInstructions (example): A coded concept identifying additional instructions such as "take with water" or "avoid operating heavy machinery". ele-1: All FHIR elements must have a @value or children
site	Σ	0..1	CodeableConcept	Specifies, where appropriate, the exact point on the body where the product is to be applied to the patient Binding: SNOMEDCTAnatomicalStructureAdministrationSites (example): A coded concept describing the site location the medicine enters into or onto the body. ele-1: All FHIR elements must have a @value or children
route	Σ	0..1	CodeableConcept	Specifies the route of administration of the product Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject. ele-1: All FHIR elements must have a @value or children
method	Σ	0..1	CodeableConcept	Type of prescription element Binding: Type de l'élément d'administration Value Set (required) ele-1: All FHIR elements must have a @value or children
dosageInstruction:posology		0..*	Dosage	Specific instructions for how the medication should be taken ele-1: All FHIR elements must have a @value or children
id		1..1	id	Unique id for inter-element referencing Required Pattern: posology
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
substitution	S	0..1	BackboneElement	Characterises a prescription item added by the pharmacist, either as a proposed replacement or as a suggestion ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
allowed[x]		1..1		Whether substitution is allowed or not Binding: ActSubstanceAdminSubstitutionCode (preferred): Identifies the type of substitution allowed. ele-1: All FHIR elements must have a @value or children
allowedBoolean			boolean
allowedCodeableConcept			CodeableConcept
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationRequest.identifier.use	required	IdentifierUse http://hl7.org/fhir/ValueSet/identifier-use|5.0.0 from the FHIR Standard
MedicationRequest.groupIdentifier.use	required	IdentifierUse http://hl7.org/fhir/ValueSet/identifier-use|5.0.0 from the FHIR Standard
MedicationRequest.status	required	MedicationrequestStatus http://hl7.org/fhir/ValueSet/medicationrequest-status|5.0.0 from the FHIR Standard
MedicationRequest.intent	required	MedicationRequestIntent http://hl7.org/fhir/ValueSet/medicationrequest-intent|5.0.0 from the FHIR Standard
MedicationRequest.priority	required	RequestPriority http://hl7.org/fhir/ValueSet/request-priority|5.0.0 from the FHIR Standard
MedicationRequest.medication	required	ConceptMedicationOncoFAIRValueSet (a valid code from Concepts Medication Code System) http://ltsi.univ-rennes.fr/ValueSet/concept-medication-oncofair-valueset from this IG
MedicationRequest.dosageInstruction:element.additionalInstruction	example	SNOMEDCTAdditionalDosageInstructions http://hl7.org/fhir/ValueSet/additional-instruction-codes from the FHIR Standard
MedicationRequest.dosageInstruction:element.site	example	SNOMEDCTAnatomicalStructureAdministrationSites http://hl7.org/fhir/ValueSet/approach-site-codes from the FHIR Standard
MedicationRequest.dosageInstruction:element.route	example	SNOMEDCTRouteCodes http://hl7.org/fhir/ValueSet/route-codes from the FHIR Standard
MedicationRequest.dosageInstruction:element.method	required	SIPhTypeEltPLAOncoFAIRValueSet (a valid code from Type de l'élément d'administration Code System) http://ltsi.univ-rennes.fr/ValueSet/siph-typeeltpla-oncofair-valueset from this IG
MedicationRequest.substitution.allowed[x]	preferred	ActSubstanceAdminSubstitutionCode http://terminology.hl7.org/ValueSet/v3-ActSubstanceAdminSubstitutionCode

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationRequest	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationRequest	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationRequest	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationRequest	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationRequest	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()