OncoFAIR
0.1.0 - ci-build

OncoFAIR - Local Development build (v0.1.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

Resource Profile: OncoFAIRMedicationRequestElement - Detailed Descriptions

Draft as of 2025-05-22

Definitions for the oncofair-medicationrequest-element resource profile.

Guidance on how to interpret the contents of this table can be found here

0. MedicationRequest
Definition

An order or request for both supply of the medication and the instructions for administration of the medication to a patient. The resource is called "MedicationRequest" rather than "MedicationPrescription" or "MedicationOrder" to generalize the use across inpatient and outpatient settings, including care plans, etc., and to harmonize with workflow patterns.

ShortOrdering of medication for patient or group
Control0..*
Is Modifierfalse
Must Supportfalse
Summaryfalse
Alternate NamesPrescription, Order
Invariantsdom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources (contained.contained.empty())
dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource (contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty())
dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated (contained.meta.versionId.empty() and contained.meta.lastUpdated.empty())
dom-5: If a resource is contained in another resource, it SHALL NOT have a security label (contained.meta.security.empty())
dom-6: A resource should have narrative for robust management (text.`div`.exists())
2. MedicationRequest.implicitRules
Definition

A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.

ShortA set of rules under which this content was created
Comments

Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of its narrative along with other profiles, value sets, etc.

Control0..1
Typeuri
Is Modifiertrue because This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies its meaning or interpretation
Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
Must Supportfalse
Summarytrue
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
4. MedicationRequest.contained
Definition

These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, nor can they have their own independent transaction scope. This is allowed to be a Parameters resource if and only if it is referenced by a resource that provides context/meaning.

ShortContained, inline Resources
Comments

This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags in their meta elements, but SHALL NOT have security labels.

Control0..*
This element is affected by the following invariants: dom-2, dom-4, dom-3, dom-5
TypeResource
Is Modifierfalse
Must Supportfalse
Summaryfalse
Alternate Namesinline resources, anonymous resources, contained resources
6. MedicationRequest.extension
Definition

An Extension


May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

ShortExtensionAdditional content defined by implementations
Comments

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Control0..*
TypeExtension
Is Modifierfalse
Must Supportfalse
Summaryfalse
Alternate Namesextensions, user content
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
SlicingThis element introduces a set of slices on MedicationRequest.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
  • value @ url
  • 8. MedicationRequest.extension:oncofair-element-form
    Slice Nameoncofair-element-form
    Definition

    Extension created as part of OncoFair containing the drug form.

    Extension créée dans le cadre d'OncoFair contenant la forme du médicament.

    ShortPharmaceutical form of the prescription/administration item
    Control0..1
    TypeExtension(OncoFAIRElementForm) (Extension Type: CodeableConcept)
    Is Modifierfalse
    Must Supporttrue
    Summaryfalse
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    10. MedicationRequest.extension:oncofair-mr-element-supply
    Slice Nameoncofair-mr-element-supply
    Definition

    Extension created as part of OncoFAIR containing the concept of supply.

    Extension créée dans le cadre d'OncoFAIR contenant la notion de fourniture.

    ShortSpecifies whether the prescription item must be supplied by the pharmacy or not
    Control0..1
    TypeExtension(OncoFAIRMRElementSupply) (Extension Type: boolean)
    Is Modifierfalse
    Must Supporttrue
    Summaryfalse
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    12. MedicationRequest.extension:oncofair-mr-element-rank
    Slice Nameoncofair-mr-element-rank
    Definition

    Extension created as part of OncoFAIR containing the prescription element rank.

    Extension créée dans le cadre d'OncoFAIR contenant le rangd d'élement de la prescription.

    ShortGives the rank of the prescription element in the prescription according to a total order of prescription elements on the prescription object to which they are attached.
    Control0..1
    TypeExtension(OncoFAIRMRElementRank) (Extension Type: integer)
    Is Modifierfalse
    Must Supporttrue
    Summaryfalse
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    14. MedicationRequest.extension:oncofair-mr-element-go-nogo
    Slice Nameoncofair-mr-element-go-nogo
    Definition

    Extension created as part of OncoFAIR containing the concept of GoNogo.

    Extension créée dans le cadre d'OncoFAIR contenant la notion de GoNogo.

    ShortOncoFAIRMRElementGoNogo
    Control0..1
    TypeExtension(OncoFAIRMRElementGoNogo) (Complex Extension)
    Is Modifierfalse
    Must Supporttrue
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    16. MedicationRequest.extension:oncofair-pharmacist-advice
    Slice Nameoncofair-pharmacist-advice
    Definition

    Extension created as part of OncoFAIR containing the validation and pharmaceutical proposal.

    Extension créée dans le cadre d'OncoFAIR contenant la validation et proposition pharmaceutique.

    ShortOncoFAIRPharmacistAdvice
    Control0..1
    TypeExtension(OncoFAIRPharmacistAdvice) (Complex Extension)
    Is Modifierfalse
    Must Supporttrue
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    18. MedicationRequest.modifierExtension
    Definition

    May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

    Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

    ShortExtensions that cannot be ignored
    Comments

    There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

    Control0..*
    TypeExtension
    Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them
    Must Supportfalse
    Summarytrue
    Requirements

    Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

    Alternate Namesextensions, user content
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
    20. MedicationRequest.identifier
    Definition

    Identifiers associated with this medication request that are defined by business processes and/or used to refer to it when a direct URL reference to the resource itself is not appropriate. They are business identifiers assigned to this resource by the performer or other systems and remain constant as the resource is updated and propagates from server to server.

    ShortUnique identifier of the prescription item by the prescriberExternal ids for this request
    Comments

    This is a business identifier, not a resource identifier.

    NoteThis is a business identifier, not a resource identifier (see discussion)
    Control10..1*
    TypeIdentifier
    Is Modifierfalse
    Must Supporttrue
    Summaryfalse
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    22. MedicationRequest.identifier.use
    Definition

    The purpose of this identifier.

    Shortusual | official | temp | secondary | old (If known)
    Comments

    Applications can assume that an identifier is permanent unless it explicitly says that it is temporary.

    Control0..1
    BindingThe codes SHALL be taken from IdentifierUsehttp://hl7.org/fhir/ValueSet/identifier-use|5.0.0
    (required to http://hl7.org/fhir/ValueSet/identifier-use|5.0.0)

    Identifies the purpose for this identifier, if known .

    Typecode
    Is Modifiertrue because This is labeled as "Is Modifier" because applications should not mistake a temporary id for a permanent one.
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Summarytrue
    Requirements

    Allows the appropriate identifier for a particular context of use to be selected from among a set of identifiers.

    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    24. MedicationRequest.identifier.value
    Definition

    The portion of the identifier typically relevant to the user and which is unique within the context of the system.

    ShortThe value that is unique
    Comments

    If the value is a full URI, then the system SHALL be urn:ietf:rfc:3986. The value's primary purpose is computational mapping. As a result, it may be normalized for comparison purposes (e.g. removing non-significant whitespace, dashes, etc.) A value formatted for human display can be conveyed using the http://hl7.org/fhir/StructureDefinition/rendered-value). Identifier.value is to be treated as case sensitive unless knowledge of the Identifier.system allows the processer to be confident that non-case-sensitive processing is safe.

    Control10..1
    This element is affected by the following invariants: ident-1
    Typestring
    Is Modifierfalse
    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
    Summarytrue
    Example<br/><b>General</b>:123456
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    26. MedicationRequest.basedOn
    Definition

    A plan or request that is fulfilled in whole or in part by this medication request.

    ShortA plan or request that is fulfilled in whole or in part by this medication request
    Control10..*
    TypeReference(CarePlan, MedicationRequest, ServiceRequest, ImmunizationRecommendation)
    Is Modifierfalse
    Must Supporttrue
    Must Support TypesNo must-support rules about the choice of types/profiles
    Summarytrue
    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
    SlicingThis element introduces a set of slices on MedicationRequest.basedOn. The slices areUnordered and Open, and can be differentiated using the following discriminators:
    • profile @ resolve()
    • 28. MedicationRequest.basedOn:prescription
      Slice Nameprescription
      Definition

      A plan or request that is fulfilled in whole or in part by this medication request.

      ShortThe prescription linked to the element of prescriptionA plan or request that is fulfilled in whole or in part by this medication request
      Control10..1*
      TypeReference(OncoFAIR MedicationRequest Prescription, CarePlan, MedicationRequest, ServiceRequest, ImmunizationRecommendation)
      Is Modifierfalse
      Must Supportfalse
      Summarytrue
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      30. MedicationRequest.basedOn:element
      Slice Nameelement
      Definition

      A plan or request that is fulfilled in whole or in part by this medication request.

      ShortThe element linked to the element of prescriptionA plan or request that is fulfilled in whole or in part by this medication request
      Control0..*
      TypeReference(OncoFAIR MedicationRequest Element, CarePlan, MedicationRequest, ServiceRequest, ImmunizationRecommendation)
      Is Modifierfalse
      Must Supportfalse
      Summarytrue
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      32. MedicationRequest.basedOn:element.extension
      Definition

      An Extension


      May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

      ShortExtensionAdditional content defined by implementations
      Comments

      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

      Control10..*
      TypeExtension
      Is Modifierfalse
      Summaryfalse
      Alternate Namesextensions, user content
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
      SlicingThis element introduces a set of slices on MedicationRequest.basedOn.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
      • value @ url
      • 34. MedicationRequest.basedOn:element.extension:oncofair-mr-element-link-type
        Slice Nameoncofair-mr-element-link-type
        Definition

        Extension created as part of OncoFAIR containing the element's type of link.

        Extension créée dans le cadre d'OncoFAIR contenant le type de liaison de l'élément.

        ShortType of link between the two prescription elements
        Control1..1
        TypeExtension(OncoFAIRMRElementLinkType) (Extension Type: CodeableConcept)
        Is Modifierfalse
        Summaryfalse
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
        36. MedicationRequest.basedOn:element.reference
        Definition

        A reference to a location at which the other resource is found. The reference may be a relative reference, in which case it is relative to the service base URL, or an absolute URL that resolves to the location where the resource is found. The reference may be version specific or not. If the reference is not to a FHIR RESTful server, then it should be assumed to be version specific. Internal fragment references (start with '#') refer to contained resources.

        ShortLiteral reference, Relative, internal or absolute URL
        Comments

        Using absolute URLs provides a stable scalable approach suitable for a cloud/web context, while using relative/logical references provides a flexible approach suitable for use when trading across closed eco-system boundaries. Absolute URLs do not need to point to a FHIR RESTful server, though this is the preferred approach. If the URL conforms to the structure "[type]/[id]" then it should be assumed that the reference is to a FHIR RESTful server.

        Control0..1
        This element is affected by the following invariants: ref-2, ref-1
        Typestring
        Is Modifierfalse
        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
        Summarytrue
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        38. MedicationRequest.basedOn:protocol
        Slice Nameprotocol
        Definition

        A plan or request that is fulfilled in whole or in part by this medication request.

        ShortThe protocol linked to the element of prescriptionA plan or request that is fulfilled in whole or in part by this medication request
        Control0..1*
        TypeReference(OncoFAIR CarePlan, CarePlan, MedicationRequest, ServiceRequest, ImmunizationRecommendation)
        Is Modifierfalse
        Must Supportfalse
        Summarytrue
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        40. MedicationRequest.groupIdentifier
        Definition

        A shared identifier common to multiple independent Request instances that were activated/authorized more or less simultaneously by a single author. The presence of the same identifier on each request ties those requests together and may have business ramifications in terms of reporting of results, billing, etc. E.g. a requisition number shared by a set of lab tests ordered together, or a prescription number shared by all meds ordered at one time.

        ShortIdentifier common to all components of the same prescriptionComposite request this is part of
        Control10..1
        TypeIdentifier
        Is Modifierfalse
        Must Supporttrue
        Summarytrue
        Requirements

        Requests are linked either by a "basedOn" relationship (i.e. one request is fulfilling another) or by having a common requisition. Requests that are part of the same requisition are generally treated independently from the perspective of changing their state or maintaining them after initial creation.

        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        42. MedicationRequest.groupIdentifier.use
        Definition

        The purpose of this identifier.

        Shortusual | official | temp | secondary | old (If known)
        Comments

        Applications can assume that an identifier is permanent unless it explicitly says that it is temporary.

        Control0..1
        BindingThe codes SHALL be taken from IdentifierUsehttp://hl7.org/fhir/ValueSet/identifier-use|5.0.0
        (required to http://hl7.org/fhir/ValueSet/identifier-use|5.0.0)

        Identifies the purpose for this identifier, if known .

        Typecode
        Is Modifiertrue because This is labeled as "Is Modifier" because applications should not mistake a temporary id for a permanent one.
        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
        Summarytrue
        Requirements

        Allows the appropriate identifier for a particular context of use to be selected from among a set of identifiers.

        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        44. MedicationRequest.groupIdentifier.value
        Definition

        The portion of the identifier typically relevant to the user and which is unique within the context of the system.

        ShortThe value that is unique
        Comments

        If the value is a full URI, then the system SHALL be urn:ietf:rfc:3986. The value's primary purpose is computational mapping. As a result, it may be normalized for comparison purposes (e.g. removing non-significant whitespace, dashes, etc.) A value formatted for human display can be conveyed using the http://hl7.org/fhir/StructureDefinition/rendered-value). Identifier.value is to be treated as case sensitive unless knowledge of the Identifier.system allows the processer to be confident that non-case-sensitive processing is safe.

        Control10..1
        This element is affected by the following invariants: ident-1
        Typestring
        Is Modifierfalse
        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
        Summarytrue
        Example<br/><b>General</b>:123456
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        46. MedicationRequest.status
        Definition

        A code specifying the current state of the order. Generally, this will be active or completed state.

        ShortIndicates the status of the protocol from the prescriber's point of viewactive | on-hold | ended | stopped | completed | cancelled | entered-in-error | draft | unknown
        Comments

        This element is labeled as a modifier because the status contains codes that mark the resource as not currently valid.

        Clinical decision support systems should take the status into account when determining which medications to include in their algorithms.

        Control1..1
        BindingThe codes SHALL be taken from MedicationrequestStatushttp://hl7.org/fhir/ValueSet/medicationrequest-status|5.0.0
        (required to http://hl7.org/fhir/ValueSet/medicationrequest-status|5.0.0)

        A coded concept specifying the state of the prescribing event. Describes the lifecycle of the prescription.

        Typecode
        Is Modifiertrue because This element is labeled as a modifier because it is a status element that contains status entered-in-error which means that the resource should not be treated as valid
        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
        Must Supporttrue
        Summarytrue
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        48. MedicationRequest.intent
        Definition

        Whether the request is a proposal, plan, or an original order.

        Shortproposal | plan | order | original-order | reflex-order | filler-order | instance-order | option
        Comments

        It is expected that the type of requester will be restricted for different stages of a MedicationRequest. For example, Proposals can be created by a patient, relatedPerson, Practitioner or Device. Plans can be created by Practitioners, Patients, RelatedPersons and Devices. Original orders can be created by a Practitioner only.

        An instance-order is an instantiation of a request or order and may be used to populate Medication Administration Record.

        This element is labeled as a modifier because the intent alters when and how the resource is actually applicable.

        Control1..1
        BindingThe codes SHALL be taken from MedicationRequestIntenthttp://hl7.org/fhir/ValueSet/medicationrequest-intent|5.0.0
        (required to http://hl7.org/fhir/ValueSet/medicationrequest-intent|5.0.0)

        The kind of medication order.

        Typecode
        Is Modifiertrue because This element changes the interpretation of all descriptive attributes. For example "the time the request is recommended to occur" vs. "the time the request is authorized to occur" or "who is recommended to perform the request" vs. "who is authorized to perform the request
        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
        Must Supportfalse
        Summarytrue
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        50. MedicationRequest.priority
        Definition

        Indicates how quickly the Medication Request should be addressed with respect to other requests.

        ShortAttribute indicating the urgency with which the prescription item must be completedroutine | urgent | asap | stat
        Control0..1
        BindingThe codes SHALL be taken from RequestPriorityhttp://hl7.org/fhir/ValueSet/request-priority|5.0.0
        (required to http://hl7.org/fhir/ValueSet/request-priority|5.0.0)

        Identifies the level of importance to be assigned to actioning the request.

        Typecode
        Is Modifierfalse
        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
        Must Supporttrue
        Summarytrue
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        52. MedicationRequest.doNotPerform
        Definition

        If true, indicates that the provider is asking for the patient to either stop taking or to not start taking the specified medication. For example, the patient is taking an existing medication and the provider is changing their medication. They want to create two seperate requests: one to stop using the current medication and another to start the new medication.

        ShortTrue if patient is to stop taking or not to start taking the medication
        Comments

        If do not perform is not specified, the request is a positive request e.g. "do perform".

        Control0..1
        Typeboolean
        Is Modifiertrue because This element is labeled as a modifier because this element negates the request to occur (ie, this is a request for the medication not to be ordered or prescribed, etc.)
        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
        Must Supportfalse
        Summarytrue
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        54. MedicationRequest.medication
        Definition

        Identifies the medication being requested. This is a link to a resource that represents the medication which may be the details of the medication or simply an attribute carrying a code that identifies the medication from a known list of medications.

        ShortMedication to be taken
        Comments

        If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the Medication resource is recommended. For example, if you require form or lot number or if the medication is compounded or extemporaneously prepared, then you must reference the Medication resource.

        Control1..1
        BindingThe codes SHALL be taken from For example codes, see Concepts Medication Value Sethttp://hl7.org/fhir/ValueSet/medication-codes
        (required to http://ltsi.univ-rennes.fr/ValueSet/concept-medication-oncofair-valueset)
        TypeCodeableReference(Medication)
        Is Modifierfalse
        Must Supporttrue
        Summarytrue
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        56. MedicationRequest.medication.concept
        Definition

        A reference to a concept - e.g. the information is identified by its general class to the degree of precision found in the terminology.

        ShortReference to a concept (by class)
        Control0..1
        TypeCodeableConcept
        Is Modifierfalse
        Summarytrue
        Pattern Value{
          "coding" : [{
            "code" : "element"
          }]
        }
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        58. MedicationRequest.subject
        Definition

        The individual or group for whom the medication has been requested.

        ShortIndividual or group for whom the medication has been requested
        Comments

        The subject on a medication request is mandatory. For the secondary use case where the actual subject is not provided, there still must be an anonymized subject specified.

        Control1..1
        TypeReference(Patient, Group)
        Is Modifierfalse
        Must Supportfalse
        Summarytrue
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        60. MedicationRequest.requester
        Definition

        The individual, organization, or device that initiated the request and has responsibility for its activation.

        ShortThe requester linked to the element of prescriptionWho/What requested the Request
        Control0..1
        TypeReference(Practitioner, PractitionerRole, Organization, Patient, RelatedPerson, Device)
        Is Modifierfalse
        Must Supporttrue
        Summarytrue
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        62. MedicationRequest.device
        Definition

        The intended type of device that is to be used for the administration of the medication (for example, PCA Pump).

        ShortSpecifies, where applicable, the medical devices or equipment to be used to administer the productIntended type of device for the administration
        Control0..*
        TypeCodeableReference(DeviceDefinition)
        Is Modifierfalse
        Must Supporttrue
        Summaryfalse
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        64. MedicationRequest.note
        Definition

        Extra information about the prescription that could not be conveyed by the other attributes.

        ShortInformation about the prescription
        Control0..*
        TypeAnnotation
        Is Modifierfalse
        Must Supporttrue
        Summaryfalse
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        SlicingThis element introduces a set of slices on MedicationRequest.note. The slices areUnordered and Open, and can be differentiated using the following discriminators:
        • value @ id
        • 66. MedicationRequest.note:wording
          Slice Namewording
          Definition

          Extra information about the prescription that could not be conveyed by the other attributes.

          ShortPrescription element wordingInformation about the prescription
          Control0..1*
          TypeAnnotation
          Is Modifierfalse
          Must Supportfalse
          Summaryfalse
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          68. MedicationRequest.note:wording.id
          Definition

          Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

          ShortUnique id for inter-element referencing
          Control10..1
          This element is affected by the following invariants: ele-1
          Typeidstring
          Is Modifierfalse
          XML FormatIn the XML format, this property is represented as an attribute.
          Summaryfalse
          Pattern Valuewording
          70. MedicationRequest.note:wording.text
          Definition

          The text of the annotation in markdown format.

          ShortThe annotation - text content (as markdown)
          Control1..1
          Typemarkdown
          Is Modifierfalse
          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
          Summarytrue
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          72. MedicationRequest.note:indication
          Slice Nameindication
          Definition

          Extra information about the prescription that could not be conveyed by the other attributes.

          ShortExplain the reasons that led the prescriber to prescribe this itemInformation about the prescription
          Control0..1*
          TypeAnnotation
          Is Modifierfalse
          Must Supportfalse
          Summaryfalse
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          74. MedicationRequest.note:indication.id
          Definition

          Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

          ShortUnique id for inter-element referencing
          Control10..1
          This element is affected by the following invariants: ele-1
          Typeidstring
          Is Modifierfalse
          XML FormatIn the XML format, this property is represented as an attribute.
          Summaryfalse
          Pattern Valueindication
          76. MedicationRequest.note:indication.text
          Definition

          The text of the annotation in markdown format.

          ShortThe annotation - text content (as markdown)
          Control1..1
          Typemarkdown
          Is Modifierfalse
          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
          Summarytrue
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          78. MedicationRequest.note:comments
          Slice Namecomments
          Definition

          Extra information about the prescription that could not be conveyed by the other attributes.

          ShortComments associated with this element, which represents the smallest entity that can be administered to the patientInformation about the prescription
          Control0..1*
          TypeAnnotation
          Is Modifierfalse
          Must Supportfalse
          Summaryfalse
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          80. MedicationRequest.note:comments.id
          Definition

          Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

          ShortUnique id for inter-element referencing
          Control10..1
          This element is affected by the following invariants: ele-1
          Typeidstring
          Is Modifierfalse
          XML FormatIn the XML format, this property is represented as an attribute.
          Summaryfalse
          Pattern Valuecomments
          82. MedicationRequest.note:comments.text
          Definition

          The text of the annotation in markdown format.

          ShortThe annotation - text content (as markdown)
          Control1..1
          Typemarkdown
          Is Modifierfalse
          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
          Summarytrue
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          84. MedicationRequest.effectiveDosePeriod
          Definition

          The period over which the medication is to be taken. Where there are multiple dosageInstruction lines (for example, tapering doses), this is the earliest date and the latest end date of the dosageInstructions.

          ShortEffective start and end date and time of product prescriptionPeriod over which the medication is to be taken
          Control0..1
          TypePeriod
          Is Modifierfalse
          Must Supporttrue
          Summaryfalse
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          86. MedicationRequest.effectiveDosePeriod.start
          Definition

          The start of the period. The boundary is inclusive.

          ShortStarting time with inclusive boundary
          Comments

          If the low element is missing, the meaning is that the low boundary is not known.

          Control0..1
          This element is affected by the following invariants: per-1
          TypedateTime
          Is Modifierfalse
          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
          Summarytrue
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          88. MedicationRequest.effectiveDosePeriod.end
          Definition

          The end of the period. If the end of the period is missing, it means no end was known or planned at the time the instance was created. The start may be in the past, and the end date in the future, which means that period is expected/planned to end at that time.

          ShortEnd time with inclusive boundary, if not ongoing
          Comments

          The end value includes any matching date/time. i.e. 2012-02-03T10:00:00 is in a period that has an end value of 2012-02-03.

          Control0..1
          This element is affected by the following invariants: per-1
          TypedateTime
          Is Modifierfalse
          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
          Summarytrue
          Meaning if MissingIf the end of the period is missing, it means that the period is ongoing
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          90. MedicationRequest.dosageInstruction
          Definition

          Specific instructions for how the medication is to be used by the patient.

          ShortSpecific instructions for how the medication should be taken
          Comments

          There are examples where a medication request may include the option of an oral dose or an Intravenous or Intramuscular dose. For example, "Ondansetron 8mg orally or IV twice a day as needed for nausea" or "Compazine® (prochlorperazine) 5-10mg PO or 25mg PR bid prn nausea or vomiting". In these cases, two medication requests would be created that could be grouped together. The decision on which dose and route of administration to use is based on the patient's condition at the time the dose is needed. In general, each prescribed drug will be a separate Medication Request.

          When drug orders are grouped together at the time of order entry, but each of the drugs can be manipulated independently e.g. changing the status of one order to "completed" or "cancelled", changing another order status to "on-hold", the method to "group" all of the medication requests together is to use MedicationRequest.groupIdentifier element. All of the orders grouped together in this manner will have the same groupIdentifier, and separately, each order in the group may have a unique identifier.

          There are cases that require grouping of Medication orders together when it is necessary to specify optionality e.g. order two drugs at one time, but stating either of these drugs may be used to treat the patient. The use of a RequestOrchestration should be used as a parent for the Medication orders that require this type of grouping. An example when it may be necessary to group medication orders together is when you specify timing relationships e.g. order drug "xyz" with dose 123, then taper the same drug to a different dose after some interval of time precedence: e.g. give drug "abc" followed by drug "def" e.g. give drug 30 minutes before some procedure was performed more generically this supports - hierarchical groups of actions, where each specific action references the action to be performed (in terms of a Request resource), and each group describes additional behavior, relationships, and applicable conditions between the actions in the overall group. Note that one should NOT use the List or Composition resource to accomplish the above requirements. You may use List or Composition for other business requirements, but not to address the specific requirements of grouping medication orders.

          Control0..*
          TypeDosage
          Is Modifierfalse
          Must Supporttrue
          Summaryfalse
          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction. The slices areUnordered and Open, and can be differentiated using the following discriminators:
          • value @ id
          • 92. MedicationRequest.dosageInstruction:element
            Slice Nameelement
            Definition

            Specific instructions for how the medication is to be used by the patient.

            ShortSpecific instructions for how the medication should be taken
            Comments

            There are examples where a medication request may include the option of an oral dose or an Intravenous or Intramuscular dose. For example, "Ondansetron 8mg orally or IV twice a day as needed for nausea" or "Compazine® (prochlorperazine) 5-10mg PO or 25mg PR bid prn nausea or vomiting". In these cases, two medication requests would be created that could be grouped together. The decision on which dose and route of administration to use is based on the patient's condition at the time the dose is needed. In general, each prescribed drug will be a separate Medication Request.

            When drug orders are grouped together at the time of order entry, but each of the drugs can be manipulated independently e.g. changing the status of one order to "completed" or "cancelled", changing another order status to "on-hold", the method to "group" all of the medication requests together is to use MedicationRequest.groupIdentifier element. All of the orders grouped together in this manner will have the same groupIdentifier, and separately, each order in the group may have a unique identifier.

            There are cases that require grouping of Medication orders together when it is necessary to specify optionality e.g. order two drugs at one time, but stating either of these drugs may be used to treat the patient. The use of a RequestOrchestration should be used as a parent for the Medication orders that require this type of grouping. An example when it may be necessary to group medication orders together is when you specify timing relationships e.g. order drug "xyz" with dose 123, then taper the same drug to a different dose after some interval of time precedence: e.g. give drug "abc" followed by drug "def" e.g. give drug 30 minutes before some procedure was performed more generically this supports - hierarchical groups of actions, where each specific action references the action to be performed (in terms of a Request resource), and each group describes additional behavior, relationships, and applicable conditions between the actions in the overall group. Note that one should NOT use the List or Composition resource to accomplish the above requirements. You may use List or Composition for other business requirements, but not to address the specific requirements of grouping medication orders.

            Control0..1*
            TypeDosage
            Is Modifierfalse
            Must Supportfalse
            Summaryfalse
            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            94. MedicationRequest.dosageInstruction:element.id
            Definition

            Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

            ShortUnique id for inter-element referencing
            Control10..1
            This element is affected by the following invariants: ele-1
            Typeidstring
            Is Modifierfalse
            XML FormatIn the XML format, this property is represented as an attribute.
            Summaryfalse
            Pattern Valueelement
            96. MedicationRequest.dosageInstruction:element.modifierExtension
            Definition

            May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

            Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

            ShortExtensions that cannot be ignored even if unrecognized
            Comments

            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

            Control0..*
            TypeExtension
            Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
            Summarytrue
            Requirements

            Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

            Alternate Namesextensions, user content, modifiers
            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
            98. MedicationRequest.dosageInstruction:element.text
            Definition

            Free text dosage instructions e.g. SIG.

            ShortDescription of the prescribed dosage, in text form.Free text dosage instructions e.g. SIG
            Control0..1
            Typestring
            Is Modifierfalse
            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
            Summarytrue
            Requirements

            Free text dosage instructions can be used for cases where the instructions are too complex to code. The content of this attribute does not include the name or description of the medication. When coded instructions are present, the free text instructions may still be present for display to humans taking or administering the medication. It is expected that the text instructions will always be populated. If the dosage.timing attribute is also populated, then the dosage.text should reflect the same information as the timing. Additional information about administration or preparation of the medication should be included as text.

            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            100. MedicationRequest.dosageInstruction:element.additionalInstruction
            Definition

            Supplemental instructions to the patient on how to take the medication (e.g. "with meals" or"take half to one hour before food") or warnings for the patient about the medication (e.g. "may cause drowsiness" or "avoid exposure of skin to direct sunlight or sunlamps").

            ShortFree text describing the conditions of application of this prescription elementSupplemental instruction or warnings to the patient - e.g. "with meals", "may cause drowsiness"
            Comments

            Information about administration or preparation of the medication (e.g. "infuse as rapidly as possibly via intraperitoneal port" or take "immediately following drug x") should be populated in dosage.text.

            Control0..1*
            BindingFor example codes, see SNOMEDCTAdditionalDosageInstructionshttp://hl7.org/fhir/ValueSet/additional-instruction-codes
            (example to http://hl7.org/fhir/ValueSet/additional-instruction-codes)

            A coded concept identifying additional instructions such as "take with water" or "avoid operating heavy machinery".

            TypeCodeableConcept
            Is Modifierfalse
            Summarytrue
            Requirements

            Additional instruction is intended to be coded, but where no code exists, the element could include text. For example, "Swallow with plenty of water" which might or might not be coded.

            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            102. MedicationRequest.dosageInstruction:element.site
            Definition

            Body site to administer to.

            ShortSpecifies, where appropriate, the exact point on the body where the product is to be applied to the patientBody site to administer to
            Comments

            If the use case requires attributes from the BodySite resource (e.g. to identify and track separately) then use the standard extension http://hl7.org/fhir/StructureDefinition/bodySite. May be a summary code, or a reference to a very precise definition of the location, or both.

            Control0..1
            BindingFor example codes, see SNOMEDCTAnatomicalStructureAdministrationSiteshttp://hl7.org/fhir/ValueSet/approach-site-codes
            (example to http://hl7.org/fhir/ValueSet/approach-site-codes)

            A coded concept describing the site location the medicine enters into or onto the body.

            TypeCodeableConcept
            Is Modifierfalse
            Summarytrue
            Requirements

            A coded specification of the anatomic site where the medication first enters the body.

            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            104. MedicationRequest.dosageInstruction:element.route
            Definition

            How drug should enter body.

            ShortSpecifies the route of administration of the productHow drug should enter body
            Control0..1
            BindingFor example codes, see SNOMEDCTRouteCodeshttp://hl7.org/fhir/ValueSet/route-codes
            (example to http://hl7.org/fhir/ValueSet/route-codes)

            A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.

            TypeCodeableConcept
            Is Modifierfalse
            Summarytrue
            Requirements

            A code specifying the route or physiological path of administration of a therapeutic agent into or onto a patient's body.

            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            106. MedicationRequest.dosageInstruction:element.method
            Definition

            Technique for administering medication.

            ShortType of prescription elementTechnique for administering medication
            Comments

            Terminologies used often pre-coordinate this term with the route and or form of administration.

            Control0..1
            BindingThe codes SHALL be taken from For example codes, see Type de l'élément d'administration Value Sethttp://hl7.org/fhir/ValueSet/administration-method-codes
            (required to http://ltsi.univ-rennes.fr/ValueSet/siph-typeeltpla-oncofair-valueset)
            TypeCodeableConcept
            Is Modifierfalse
            Summarytrue
            Requirements

            A coded value indicating the method by which the medication is introduced into or onto the body. Most commonly used for injections. For examples, Slow Push; Deep IV.

            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            108. MedicationRequest.dosageInstruction:posology
            Slice Nameposology
            Definition

            Specific instructions for how the medication is to be used by the patient.

            ShortSpecific instructions for how the medication should be taken
            Comments

            There are examples where a medication request may include the option of an oral dose or an Intravenous or Intramuscular dose. For example, "Ondansetron 8mg orally or IV twice a day as needed for nausea" or "Compazine® (prochlorperazine) 5-10mg PO or 25mg PR bid prn nausea or vomiting". In these cases, two medication requests would be created that could be grouped together. The decision on which dose and route of administration to use is based on the patient's condition at the time the dose is needed. In general, each prescribed drug will be a separate Medication Request.

            When drug orders are grouped together at the time of order entry, but each of the drugs can be manipulated independently e.g. changing the status of one order to "completed" or "cancelled", changing another order status to "on-hold", the method to "group" all of the medication requests together is to use MedicationRequest.groupIdentifier element. All of the orders grouped together in this manner will have the same groupIdentifier, and separately, each order in the group may have a unique identifier.

            There are cases that require grouping of Medication orders together when it is necessary to specify optionality e.g. order two drugs at one time, but stating either of these drugs may be used to treat the patient. The use of a RequestOrchestration should be used as a parent for the Medication orders that require this type of grouping. An example when it may be necessary to group medication orders together is when you specify timing relationships e.g. order drug "xyz" with dose 123, then taper the same drug to a different dose after some interval of time precedence: e.g. give drug "abc" followed by drug "def" e.g. give drug 30 minutes before some procedure was performed more generically this supports - hierarchical groups of actions, where each specific action references the action to be performed (in terms of a Request resource), and each group describes additional behavior, relationships, and applicable conditions between the actions in the overall group. Note that one should NOT use the List or Composition resource to accomplish the above requirements. You may use List or Composition for other business requirements, but not to address the specific requirements of grouping medication orders.

            Control0..*
            TypeDosage
            Is Modifierfalse
            Must Supportfalse
            Summaryfalse
            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            110. MedicationRequest.dosageInstruction:posology.id
            Definition

            Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

            ShortUnique id for inter-element referencing
            Control10..1
            This element is affected by the following invariants: ele-1
            Typeidstring
            Is Modifierfalse
            XML FormatIn the XML format, this property is represented as an attribute.
            Summaryfalse
            Pattern Valueposology
            112. MedicationRequest.dosageInstruction:posology.modifierExtension
            Definition

            May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

            Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

            ShortExtensions that cannot be ignored even if unrecognized
            Comments

            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

            Control0..*
            TypeExtension
            Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
            Summarytrue
            Requirements

            Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

            Alternate Namesextensions, user content, modifiers
            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
            114. MedicationRequest.substitution
            Definition

            Indicates whether or not substitution can or should be part of the dispense. In some cases, substitution must happen, in other cases substitution must not happen. This block explains the prescriber's intent. If nothing is specified substitution may be done.

            ShortCharacterises a prescription item added by the pharmacist, either as a proposed replacement or as a suggestionAny restrictions on medication substitution
            Control0..1
            TypeBackboneElement
            Is Modifierfalse
            Must Supporttrue
            Summaryfalse
            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            116. MedicationRequest.substitution.modifierExtension
            Definition

            May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

            Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

            ShortExtensions that cannot be ignored even if unrecognized
            Comments

            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

            Control0..*
            TypeExtension
            Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
            Summarytrue
            Requirements

            Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

            Alternate Namesextensions, user content, modifiers
            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
            118. MedicationRequest.substitution.allowed[x]
            Definition

            True if the prescriber allows a different drug to be dispensed from what was prescribed.

            ShortWhether substitution is allowed or not
            Comments

            This element is labeled as a modifier because whether substitution is allow or not, it cannot be ignored.

            Control1..1
            BindingThe codes SHOULD be taken from ActSubstanceAdminSubstitutionCodehttp://terminology.hl7.org/ValueSet/v3-ActSubstanceAdminSubstitutionCode
            (preferred to http://terminology.hl7.org/ValueSet/v3-ActSubstanceAdminSubstitutionCode)

            Identifies the type of substitution allowed.

            TypeChoice of: boolean, CodeableConcept
            [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
            Is Modifierfalse
            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
            Must Supportfalse
            Summaryfalse
            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))

            Guidance on how to interpret the contents of this table can be found here

            0. MedicationRequest
            2. MedicationRequest.extension
            SlicingThis element introduces a set of slices on MedicationRequest.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
            • value @ url
            • 4. MedicationRequest.extension:oncofair-element-form
              Slice Nameoncofair-element-form
              Control0..1
              TypeExtension(OncoFAIRElementForm) (Extension Type: CodeableConcept)
              Must Supporttrue
              6. MedicationRequest.extension:oncofair-mr-element-supply
              Slice Nameoncofair-mr-element-supply
              Control0..1
              TypeExtension(OncoFAIRMRElementSupply) (Extension Type: boolean)
              Must Supporttrue
              8. MedicationRequest.extension:oncofair-mr-element-rank
              Slice Nameoncofair-mr-element-rank
              Control0..1
              TypeExtension(OncoFAIRMRElementRank) (Extension Type: integer)
              Must Supporttrue
              10. MedicationRequest.extension:oncofair-mr-element-go-nogo
              Slice Nameoncofair-mr-element-go-nogo
              Control0..1
              TypeExtension(OncoFAIRMRElementGoNogo) (Complex Extension)
              Must Supporttrue
              12. MedicationRequest.extension:oncofair-pharmacist-advice
              Slice Nameoncofair-pharmacist-advice
              Control0..1
              TypeExtension(OncoFAIRPharmacistAdvice) (Complex Extension)
              Must Supporttrue
              14. MedicationRequest.identifier
              ShortUnique identifier of the prescription item by the prescriber
              NoteThis is a business identifier, not a resource identifier (see discussion)
              Control1..1
              Must Supporttrue
              16. MedicationRequest.identifier.value
              Control1..?
              18. MedicationRequest.basedOn
              Control1..?
              Must Supporttrue
              SlicingThis element introduces a set of slices on MedicationRequest.basedOn. The slices areUnordered and Open, and can be differentiated using the following discriminators:
              • profile @ resolve()
              • 20. MedicationRequest.basedOn:prescription
                Slice Nameprescription
                ShortThe prescription linked to the element of prescription
                Control1..1
                TypeReference(OncoFAIR MedicationRequest Prescription)
                22. MedicationRequest.basedOn:element
                Slice Nameelement
                ShortThe element linked to the element of prescription
                Control0..*
                TypeReference(OncoFAIR MedicationRequest Element)
                24. MedicationRequest.basedOn:element.extension
                Control1..?
                26. MedicationRequest.basedOn:element.extension:oncofair-mr-element-link-type
                Slice Nameoncofair-mr-element-link-type
                Control1..1
                TypeExtension(OncoFAIRMRElementLinkType) (Extension Type: CodeableConcept)
                28. MedicationRequest.basedOn:protocol
                Slice Nameprotocol
                ShortThe protocol linked to the element of prescription
                Control0..1
                TypeReference(OncoFAIR CarePlan)
                30. MedicationRequest.groupIdentifier
                ShortIdentifier common to all components of the same prescription
                Control1..?
                Must Supporttrue
                32. MedicationRequest.groupIdentifier.value
                Control1..?
                34. MedicationRequest.status
                ShortIndicates the status of the protocol from the prescriber's point of view
                Must Supporttrue
                36. MedicationRequest.priority
                ShortAttribute indicating the urgency with which the prescription item must be completed
                Must Supporttrue
                38. MedicationRequest.medication
                BindingThe codes SHALL be taken from Concepts Medication Value Set
                (required to http://ltsi.univ-rennes.fr/ValueSet/concept-medication-oncofair-valueset)
                Must Supporttrue
                40. MedicationRequest.medication.concept
                Pattern Value{
                  "coding" : [{
                    "code" : "element"
                  }]
                }
                42. MedicationRequest.requester
                ShortThe requester linked to the element of prescription
                TypeReference(Practitioner)
                Must Supporttrue
                44. MedicationRequest.device
                ShortSpecifies, where applicable, the medical devices or equipment to be used to administer the product
                Must Supporttrue
                46. MedicationRequest.note
                Must Supporttrue
                SlicingThis element introduces a set of slices on MedicationRequest.note. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                • value @ id
                • 48. MedicationRequest.note:wording
                  Slice Namewording
                  ShortPrescription element wording
                  Control0..1
                  50. MedicationRequest.note:wording.id
                  Control1..?
                  Pattern Valuewording
                  52. MedicationRequest.note:indication
                  Slice Nameindication
                  ShortExplain the reasons that led the prescriber to prescribe this item
                  Control0..1
                  54. MedicationRequest.note:indication.id
                  Control1..?
                  Pattern Valueindication
                  56. MedicationRequest.note:comments
                  Slice Namecomments
                  ShortComments associated with this element, which represents the smallest entity that can be administered to the patient
                  Control0..1
                  58. MedicationRequest.note:comments.id
                  Control1..?
                  Pattern Valuecomments
                  60. MedicationRequest.effectiveDosePeriod
                  ShortEffective start and end date and time of product prescription
                  Must Supporttrue
                  62. MedicationRequest.effectiveDosePeriod.start
                  64. MedicationRequest.effectiveDosePeriod.end
                  66. MedicationRequest.dosageInstruction
                  Must Supporttrue
                  SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                  • value @ id
                  • 68. MedicationRequest.dosageInstruction:element
                    Slice Nameelement
                    Control0..1
                    70. MedicationRequest.dosageInstruction:element.id
                    Control1..?
                    Pattern Valueelement
                    72. MedicationRequest.dosageInstruction:element.text
                    ShortDescription of the prescribed dosage, in text form.
                    74. MedicationRequest.dosageInstruction:element.additionalInstruction
                    ShortFree text describing the conditions of application of this prescription element
                    Control0..1
                    76. MedicationRequest.dosageInstruction:element.timing
                    78. MedicationRequest.dosageInstruction:element.timing.repeat
                    80. MedicationRequest.dosageInstruction:element.timing.repeat.bounds[x]
                    [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                    SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction.timing.repeat.bounds[x]. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                    • type @ $this
                    • 82. MedicationRequest.dosageInstruction:element.timing.repeat.bounds[x]:boundsPeriod
                      Slice NameboundsPeriod
                      Control0..1
                      TypePeriod
                      [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                      84. MedicationRequest.dosageInstruction:element.timing.repeat.bounds[x]:boundsPeriod.start
                      ShortPrescribed start date and time of product prescription
                      86. MedicationRequest.dosageInstruction:element.timing.repeat.bounds[x]:boundsPeriod.end
                      ShortPrescribed end date and time of product prescription
                      88. MedicationRequest.dosageInstruction:element.timing.repeat.offset
                      ShortDecimal value, positive or negative, of the interval between the reference date/time of the prescribed protocol and that of this prescription item
                      90. MedicationRequest.dosageInstruction:element.site
                      ShortSpecifies, where appropriate, the exact point on the body where the product is to be applied to the patient
                      92. MedicationRequest.dosageInstruction:element.route
                      ShortSpecifies the route of administration of the product
                      94. MedicationRequest.dosageInstruction:element.method
                      ShortType of prescription element
                      BindingThe codes SHALL be taken from Type de l'élément d'administration Value Set
                      (required to http://ltsi.univ-rennes.fr/ValueSet/siph-typeeltpla-oncofair-valueset)
                      96. MedicationRequest.dosageInstruction:posology
                      Slice Nameposology
                      Control0..*
                      98. MedicationRequest.dosageInstruction:posology.id
                      Control1..?
                      Pattern Valueposology
                      100. MedicationRequest.dosageInstruction:posology.timing
                      102. MedicationRequest.dosageInstruction:posology.timing.repeat
                      104. MedicationRequest.dosageInstruction:posology.timing.repeat.duration
                      ShortDuration of administration
                      106. MedicationRequest.dosageInstruction:posology.timing.repeat.frequency
                      ShortIndicates the recurrence of the dosage. By default, every day
                      108. MedicationRequest.dosageInstruction:posology.doseAndRate
                      110. MedicationRequest.dosageInstruction:posology.doseAndRate.dose[x]
                      [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                      SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction.doseAndRate.dose[x]. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                      • type @ $this
                      • 112. MedicationRequest.dosageInstruction:posology.doseAndRate.dose[x]:doseQuantity
                        Slice NamedoseQuantity
                        ShortQuantity of the prescription element in the dosage
                        Control0..1
                        TypeQuantity(SimpleQuantity)
                        [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                        114. MedicationRequest.dosageInstruction:posology.doseAndRate.rate[x]
                        [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                        SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction.doseAndRate.rate[x]. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                        • type @ $this
                        • 116. MedicationRequest.dosageInstruction:posology.doseAndRate.rate[x]:rateQuantity
                          Slice NamerateQuantity
                          ShortRate of administration in the case of injection
                          Control0..1
                          TypeQuantity(SimpleQuantity)
                          [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                          118. MedicationRequest.substitution
                          ShortCharacterises a prescription item added by the pharmacist, either as a proposed replacement or as a suggestion
                          Must Supporttrue

                          Guidance on how to interpret the contents of this table can be found here

                          0. MedicationRequest
                          Definition

                          An order or request for both supply of the medication and the instructions for administration of the medication to a patient. The resource is called "MedicationRequest" rather than "MedicationPrescription" or "MedicationOrder" to generalize the use across inpatient and outpatient settings, including care plans, etc., and to harmonize with workflow patterns.

                          ShortOrdering of medication for patient or group
                          Control0..*
                          Is Modifierfalse
                          Must Supportfalse
                          Summaryfalse
                          Alternate NamesPrescription, Order
                          Invariantsdom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources (contained.contained.empty())
                          dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource (contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofType(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url))) or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical) = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmatched', id).empty())
                          dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated (contained.meta.versionId.empty() and contained.meta.lastUpdated.empty())
                          dom-5: If a resource is contained in another resource, it SHALL NOT have a security label (contained.meta.security.empty())
                          dom-6: A resource should have narrative for robust management (text.`div`.exists())
                          2. MedicationRequest.id
                          Definition

                          The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.

                          ShortLogical id of this artifact
                          Comments

                          Within the context of the FHIR RESTful interactions, the resource has an id except for cases like the create and conditional update. Otherwise, the use of the resouce id depends on the given use case.

                          Control0..1
                          Typeid
                          Is Modifierfalse
                          Must Supportfalse
                          Summarytrue
                          4. MedicationRequest.meta
                          Definition

                          The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.

                          ShortMetadata about the resource
                          Control0..1
                          TypeMeta
                          Is Modifierfalse
                          Must Supportfalse
                          Summarytrue
                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          6. MedicationRequest.implicitRules
                          Definition

                          A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.

                          ShortA set of rules under which this content was created
                          Comments

                          Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of its narrative along with other profiles, value sets, etc.

                          Control0..1
                          Typeuri
                          Is Modifiertrue because This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies its meaning or interpretation
                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                          Must Supportfalse
                          Summarytrue
                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          8. MedicationRequest.language
                          Definition

                          The base language in which the resource is written.

                          ShortLanguage of the resource content
                          Comments

                          Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).

                          Control0..1
                          BindingThe codes SHALL be taken from AllLanguages
                          (required to http://hl7.org/fhir/ValueSet/all-languages|5.0.0)

                          IETF language tag for a human language

                          Typecode
                          Is Modifierfalse
                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                          Must Supportfalse
                          Summaryfalse
                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          10. MedicationRequest.text
                          Definition

                          A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it "clinically safe" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.

                          ShortText summary of the resource, for human interpretation
                          Comments

                          Contained resources do not have a narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a "text blob" or where text is additionally entered raw or narrated and encoded information is added later.

                          Control0..1
                          This element is affected by the following invariants: dom-6
                          TypeNarrative
                          Is Modifierfalse
                          Must Supportfalse
                          Summaryfalse
                          Alternate Namesnarrative, html, xhtml, display
                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          12. MedicationRequest.contained
                          Definition

                          These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, nor can they have their own independent transaction scope. This is allowed to be a Parameters resource if and only if it is referenced by a resource that provides context/meaning.

                          ShortContained, inline Resources
                          Comments

                          This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags in their meta elements, but SHALL NOT have security labels.

                          Control0..*
                          This element is affected by the following invariants: dom-2, dom-4, dom-3, dom-5
                          TypeResource
                          Is Modifierfalse
                          Must Supportfalse
                          Summaryfalse
                          Alternate Namesinline resources, anonymous resources, contained resources
                          14. MedicationRequest.extension
                          Definition

                          An Extension

                          ShortExtension
                          Control0..*
                          TypeExtension
                          Is Modifierfalse
                          Must Supportfalse
                          Summaryfalse
                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                          SlicingThis element introduces a set of slices on MedicationRequest.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                          • value @ url
                          • 16. MedicationRequest.extension:oncofair-element-form
                            Slice Nameoncofair-element-form
                            Definition

                            Extension created as part of OncoFair containing the drug form.

                            Extension créée dans le cadre d'OncoFair contenant la forme du médicament.

                            ShortPharmaceutical form of the prescription/administration item
                            Control0..1
                            TypeExtension(OncoFAIRElementForm) (Extension Type: CodeableConcept)
                            Is Modifierfalse
                            Must Supporttrue
                            Summaryfalse
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                            18. MedicationRequest.extension:oncofair-mr-element-supply
                            Slice Nameoncofair-mr-element-supply
                            Definition

                            Extension created as part of OncoFAIR containing the concept of supply.

                            Extension créée dans le cadre d'OncoFAIR contenant la notion de fourniture.

                            ShortSpecifies whether the prescription item must be supplied by the pharmacy or not
                            Control0..1
                            TypeExtension(OncoFAIRMRElementSupply) (Extension Type: boolean)
                            Is Modifierfalse
                            Must Supporttrue
                            Summaryfalse
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                            20. MedicationRequest.extension:oncofair-mr-element-rank
                            Slice Nameoncofair-mr-element-rank
                            Definition

                            Extension created as part of OncoFAIR containing the prescription element rank.

                            Extension créée dans le cadre d'OncoFAIR contenant le rangd d'élement de la prescription.

                            ShortGives the rank of the prescription element in the prescription according to a total order of prescription elements on the prescription object to which they are attached.
                            Control0..1
                            TypeExtension(OncoFAIRMRElementRank) (Extension Type: integer)
                            Is Modifierfalse
                            Must Supporttrue
                            Summaryfalse
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                            22. MedicationRequest.extension:oncofair-mr-element-go-nogo
                            Slice Nameoncofair-mr-element-go-nogo
                            Definition

                            Extension created as part of OncoFAIR containing the concept of GoNogo.

                            Extension créée dans le cadre d'OncoFAIR contenant la notion de GoNogo.

                            ShortOncoFAIRMRElementGoNogo
                            Control0..1
                            TypeExtension(OncoFAIRMRElementGoNogo) (Complex Extension)
                            Is Modifierfalse
                            Must Supporttrue
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                            24. MedicationRequest.extension:oncofair-pharmacist-advice
                            Slice Nameoncofair-pharmacist-advice
                            Definition

                            Extension created as part of OncoFAIR containing the validation and pharmaceutical proposal.

                            Extension créée dans le cadre d'OncoFAIR contenant la validation et proposition pharmaceutique.

                            ShortOncoFAIRPharmacistAdvice
                            Control0..1
                            TypeExtension(OncoFAIRPharmacistAdvice) (Complex Extension)
                            Is Modifierfalse
                            Must Supporttrue
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                            26. MedicationRequest.modifierExtension
                            Definition

                            May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                            Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                            ShortExtensions that cannot be ignored
                            Comments

                            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                            Control0..*
                            TypeExtension
                            Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them
                            Must Supportfalse
                            Summarytrue
                            Requirements

                            Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                            Alternate Namesextensions, user content
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                            28. MedicationRequest.identifier
                            Definition

                            Identifiers associated with this medication request that are defined by business processes and/or used to refer to it when a direct URL reference to the resource itself is not appropriate. They are business identifiers assigned to this resource by the performer or other systems and remain constant as the resource is updated and propagates from server to server.

                            ShortUnique identifier of the prescription item by the prescriber
                            Comments

                            This is a business identifier, not a resource identifier.

                            NoteThis is a business identifier, not a resource identifier (see discussion)
                            Control1..1
                            TypeIdentifier
                            Is Modifierfalse
                            Must Supporttrue
                            Summaryfalse
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            30. MedicationRequest.identifier.id
                            Definition

                            Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                            ShortUnique id for inter-element referencing
                            Control0..1
                            This element is affected by the following invariants: ele-1
                            Typeid
                            Is Modifierfalse
                            XML FormatIn the XML format, this property is represented as an attribute.
                            Summaryfalse
                            32. MedicationRequest.identifier.extension
                            Definition

                            May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                            ShortAdditional content defined by implementations
                            Comments

                            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                            Control0..*
                            TypeExtension
                            Is Modifierfalse
                            Summaryfalse
                            Alternate Namesextensions, user content
                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                            SlicingThis element introduces a set of slices on MedicationRequest.identifier.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                            • value @ url
                            • 34. MedicationRequest.identifier.use
                              Definition

                              The purpose of this identifier.

                              Shortusual | official | temp | secondary | old (If known)
                              Comments

                              Applications can assume that an identifier is permanent unless it explicitly says that it is temporary.

                              Control0..1
                              BindingThe codes SHALL be taken from IdentifierUse
                              (required to http://hl7.org/fhir/ValueSet/identifier-use|5.0.0)

                              Identifies the purpose for this identifier, if known .

                              Typecode
                              Is Modifiertrue because This is labeled as "Is Modifier" because applications should not mistake a temporary id for a permanent one.
                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                              Summarytrue
                              Requirements

                              Allows the appropriate identifier for a particular context of use to be selected from among a set of identifiers.

                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              36. MedicationRequest.identifier.type
                              Definition

                              A coded type for the identifier that can be used to determine which identifier to use for a specific purpose.

                              ShortDescription of identifier
                              Comments

                              This element deals only with general categories of identifiers. It SHOULD not be used for codes that correspond 1..1 with the Identifier.system. Some identifiers may fall into multiple categories due to common usage. Where the system is known, a type is unnecessary because the type is always part of the system definition. However systems often need to handle identifiers where the system is not known. There is not a 1:1 relationship between type and system, since many different systems have the same type.

                              Control0..1
                              BindingUnless not suitable, these codes SHALL be taken from IdentifierTypeCodes
                              (extensible to http://hl7.org/fhir/ValueSet/identifier-type)

                              A coded type for an identifier that can be used to determine which identifier to use for a specific purpose.

                              TypeCodeableConcept
                              Is Modifierfalse
                              Summarytrue
                              Requirements

                              Allows users to make use of identifiers when the identifier system is not known.

                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              38. MedicationRequest.identifier.system
                              Definition

                              Establishes the namespace for the value - that is, an absolute URL that describes a set values that are unique.

                              ShortThe namespace for the identifier value
                              Comments

                              Identifier.system is always case sensitive.

                              Control0..1
                              Typeuri
                              Is Modifierfalse
                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                              Summarytrue
                              Requirements

                              There are many sets of identifiers. To perform matching of two identifiers, we need to know what set we're dealing with. The system identifies a particular set of unique identifiers.

                              Example<br/><b>General</b>:http://www.acme.com/identifiers/patient
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              40. MedicationRequest.identifier.value
                              Definition

                              The portion of the identifier typically relevant to the user and which is unique within the context of the system.

                              ShortThe value that is unique
                              Comments

                              If the value is a full URI, then the system SHALL be urn:ietf:rfc:3986. The value's primary purpose is computational mapping. As a result, it may be normalized for comparison purposes (e.g. removing non-significant whitespace, dashes, etc.) A value formatted for human display can be conveyed using the http://hl7.org/fhir/StructureDefinition/rendered-value). Identifier.value is to be treated as case sensitive unless knowledge of the Identifier.system allows the processer to be confident that non-case-sensitive processing is safe.

                              Control1..1
                              This element is affected by the following invariants: ident-1
                              Typestring
                              Is Modifierfalse
                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                              Summarytrue
                              Example<br/><b>General</b>:123456
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              42. MedicationRequest.identifier.period
                              Definition

                              Time period during which identifier is/was valid for use.

                              ShortTime period when id is/was valid for use
                              Control0..1
                              TypePeriod
                              Is Modifierfalse
                              Summarytrue
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              44. MedicationRequest.identifier.assigner
                              Definition

                              Organization that issued/manages the identifier.

                              ShortOrganization that issued id (may be just text)
                              Comments

                              The Identifier.assigner may omit the .reference element and only contain a .display element reflecting the name or other textual information about the assigning organization.

                              Control0..1
                              TypeReference(Organization)
                              Is Modifierfalse
                              Summarytrue
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              46. MedicationRequest.basedOn
                              Definition

                              A plan or request that is fulfilled in whole or in part by this medication request.

                              ShortA plan or request that is fulfilled in whole or in part by this medication request
                              Control1..*
                              TypeReference(CarePlan, MedicationRequest, ServiceRequest, ImmunizationRecommendation)
                              Is Modifierfalse
                              Must Supporttrue
                              Must Support TypesNo must-support rules about the choice of types/profiles
                              Summarytrue
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                              SlicingThis element introduces a set of slices on MedicationRequest.basedOn. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                              • profile @ resolve()
                              • 48. MedicationRequest.basedOn:prescription
                                Slice Nameprescription
                                Definition

                                A plan or request that is fulfilled in whole or in part by this medication request.

                                ShortThe prescription linked to the element of prescription
                                Control1..1
                                TypeReference(OncoFAIR MedicationRequest Prescription)
                                Is Modifierfalse
                                Must Supportfalse
                                Summarytrue
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                50. MedicationRequest.basedOn:element
                                Slice Nameelement
                                Definition

                                A plan or request that is fulfilled in whole or in part by this medication request.

                                ShortThe element linked to the element of prescription
                                Control0..*
                                TypeReference(OncoFAIR MedicationRequest Element)
                                Is Modifierfalse
                                Must Supportfalse
                                Summarytrue
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                52. MedicationRequest.basedOn:element.id
                                Definition

                                Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                ShortUnique id for inter-element referencing
                                Control0..1
                                This element is affected by the following invariants: ele-1
                                Typeid
                                Is Modifierfalse
                                XML FormatIn the XML format, this property is represented as an attribute.
                                Summaryfalse
                                54. MedicationRequest.basedOn:element.extension
                                Definition

                                An Extension

                                ShortExtension
                                Control1..*
                                TypeExtension
                                Is Modifierfalse
                                Summaryfalse
                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                SlicingThis element introduces a set of slices on MedicationRequest.basedOn.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                • value @ url
                                • 56. MedicationRequest.basedOn:element.extension:oncofair-mr-element-link-type
                                  Slice Nameoncofair-mr-element-link-type
                                  Definition

                                  Extension created as part of OncoFAIR containing the element's type of link.

                                  Extension créée dans le cadre d'OncoFAIR contenant le type de liaison de l'élément.

                                  ShortType of link between the two prescription elements
                                  Control1..1
                                  TypeExtension(OncoFAIRMRElementLinkType) (Extension Type: CodeableConcept)
                                  Is Modifierfalse
                                  Summaryfalse
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                  58. MedicationRequest.basedOn:element.reference
                                  Definition

                                  A reference to a location at which the other resource is found. The reference may be a relative reference, in which case it is relative to the service base URL, or an absolute URL that resolves to the location where the resource is found. The reference may be version specific or not. If the reference is not to a FHIR RESTful server, then it should be assumed to be version specific. Internal fragment references (start with '#') refer to contained resources.

                                  ShortLiteral reference, Relative, internal or absolute URL
                                  Comments

                                  Using absolute URLs provides a stable scalable approach suitable for a cloud/web context, while using relative/logical references provides a flexible approach suitable for use when trading across closed eco-system boundaries. Absolute URLs do not need to point to a FHIR RESTful server, though this is the preferred approach. If the URL conforms to the structure "[type]/[id]" then it should be assumed that the reference is to a FHIR RESTful server.

                                  Control0..1
                                  This element is affected by the following invariants: ref-2, ref-1
                                  Typestring
                                  Is Modifierfalse
                                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                  Summarytrue
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  60. MedicationRequest.basedOn:element.type
                                  Definition

                                  The expected type of the target of the reference. If both Reference.type and Reference.reference are populated and Reference.reference is a FHIR URL, both SHALL be consistent.

                                  The type is the Canonical URL of Resource Definition that is the type this reference refers to. References are URLs that are relative to http://hl7.org/fhir/StructureDefinition/ e.g. "Patient" is a reference to http://hl7.org/fhir/StructureDefinition/Patient. Absolute URLs are only allowed for logical models (and can only be used in references in logical models, not resources).

                                  ShortType the reference refers to (e.g. "Patient") - must be a resource in resources
                                  Comments

                                  This element is used to indicate the type of the target of the reference. This may be used which ever of the other elements are populated (or not). In some cases, the type of the target may be determined by inspection of the reference (e.g. a known RESTful URL) or by resolving the target of the reference.

                                  Control0..1
                                  BindingUnless not suitable, these codes SHALL be taken from ResourceType
                                  (extensible to http://hl7.org/fhir/ValueSet/resource-types)

                                  Aa resource (or, for logical models, the URI of the logical model).

                                  Typeuri
                                  Is Modifierfalse
                                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                  Summarytrue
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  62. MedicationRequest.basedOn:element.identifier
                                  Definition

                                  An identifier for the target resource. This is used when there is no way to reference the other resource directly, either because the entity it represents is not available through a FHIR server, or because there is no way for the author of the resource to convert a known identifier to an actual location. There is no requirement that a Reference.identifier point to something that is actually exposed as a FHIR instance, but it SHALL point to a business concept that would be expected to be exposed as a FHIR instance, and that instance would need to be of a FHIR resource type allowed by the reference.

                                  ShortLogical reference, when literal reference is not known
                                  Comments

                                  When an identifier is provided in place of a reference, any system processing the reference will only be able to resolve the identifier to a reference if it understands the business context in which the identifier is used. Sometimes this is global (e.g. a national identifier) but often it is not. For this reason, none of the useful mechanisms described for working with references (e.g. chaining, includes) are possible, nor should servers be expected to be able resolve the reference. Servers may accept an identifier based reference untouched, resolve it, and/or reject it - see CapabilityStatement.rest.resource.referencePolicy.

                                  When both an identifier and a literal reference are provided, the literal reference is preferred. Applications processing the resource are allowed - but not required - to check that the identifier matches the literal reference

                                  Applications converting a logical reference to a literal reference may choose to leave the logical reference present, or remove it.

                                  Reference is intended to point to a structure that can potentially be expressed as a FHIR resource, though there is no need for it to exist as an actual FHIR resource instance - except in as much as an application wishes to actual find the target of the reference. The content referred to be the identifier must meet the logical constraints implied by any limitations on what resource types are permitted for the reference. For example, it would not be legitimate to send the identifier for a drug prescription if the type were Reference(Observation|DiagnosticReport). One of the use-cases for Reference.identifier is the situation where no FHIR representation exists (where the type is Reference (Any).

                                  This element only allows for a single identifier. In the case where additional identifers are required, use the http://hl7.org/fhir/StructureDefinition/additionalIdentifier extension.

                                  NoteThis is a business identifier, not a resource identifier (see discussion)
                                  Control0..1
                                  This element is affected by the following invariants: ref-2
                                  TypeIdentifier
                                  Is Modifierfalse
                                  Summarytrue
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  64. MedicationRequest.basedOn:element.display
                                  Definition

                                  Plain text narrative that identifies the resource in addition to the resource reference.

                                  ShortText alternative for the resource
                                  Comments

                                  This is generally not the same as the Resource.text of the referenced resource. The purpose is to identify what's being referenced, not to fully describe it.

                                  Control0..1
                                  This element is affected by the following invariants: ref-2
                                  Typestring
                                  Is Modifierfalse
                                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                  Summarytrue
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  66. MedicationRequest.basedOn:protocol
                                  Slice Nameprotocol
                                  Definition

                                  A plan or request that is fulfilled in whole or in part by this medication request.

                                  ShortThe protocol linked to the element of prescription
                                  Control0..1
                                  TypeReference(OncoFAIR CarePlan)
                                  Is Modifierfalse
                                  Must Supportfalse
                                  Summarytrue
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  68. MedicationRequest.priorPrescription
                                  Definition

                                  Reference to an order/prescription that is being replaced by this MedicationRequest.

                                  ShortReference to an order/prescription that is being replaced by this MedicationRequest
                                  Control0..1
                                  TypeReference(MedicationRequest)
                                  Is Modifierfalse
                                  Must Supportfalse
                                  Summaryfalse
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  70. MedicationRequest.groupIdentifier
                                  Definition

                                  A shared identifier common to multiple independent Request instances that were activated/authorized more or less simultaneously by a single author. The presence of the same identifier on each request ties those requests together and may have business ramifications in terms of reporting of results, billing, etc. E.g. a requisition number shared by a set of lab tests ordered together, or a prescription number shared by all meds ordered at one time.

                                  ShortIdentifier common to all components of the same prescription
                                  Control1..1
                                  TypeIdentifier
                                  Is Modifierfalse
                                  Must Supporttrue
                                  Summarytrue
                                  Requirements

                                  Requests are linked either by a "basedOn" relationship (i.e. one request is fulfilling another) or by having a common requisition. Requests that are part of the same requisition are generally treated independently from the perspective of changing their state or maintaining them after initial creation.

                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  72. MedicationRequest.groupIdentifier.id
                                  Definition

                                  Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                  ShortUnique id for inter-element referencing
                                  Control0..1
                                  This element is affected by the following invariants: ele-1
                                  Typeid
                                  Is Modifierfalse
                                  XML FormatIn the XML format, this property is represented as an attribute.
                                  Summaryfalse
                                  74. MedicationRequest.groupIdentifier.extension
                                  Definition

                                  May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                  ShortAdditional content defined by implementations
                                  Comments

                                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                  Control0..*
                                  TypeExtension
                                  Is Modifierfalse
                                  Summaryfalse
                                  Alternate Namesextensions, user content
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                  SlicingThis element introduces a set of slices on MedicationRequest.groupIdentifier.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                  • value @ url
                                  • 76. MedicationRequest.groupIdentifier.use
                                    Definition

                                    The purpose of this identifier.

                                    Shortusual | official | temp | secondary | old (If known)
                                    Comments

                                    Applications can assume that an identifier is permanent unless it explicitly says that it is temporary.

                                    Control0..1
                                    BindingThe codes SHALL be taken from IdentifierUse
                                    (required to http://hl7.org/fhir/ValueSet/identifier-use|5.0.0)

                                    Identifies the purpose for this identifier, if known .

                                    Typecode
                                    Is Modifiertrue because This is labeled as "Is Modifier" because applications should not mistake a temporary id for a permanent one.
                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                    Summarytrue
                                    Requirements

                                    Allows the appropriate identifier for a particular context of use to be selected from among a set of identifiers.

                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    78. MedicationRequest.groupIdentifier.type
                                    Definition

                                    A coded type for the identifier that can be used to determine which identifier to use for a specific purpose.

                                    ShortDescription of identifier
                                    Comments

                                    This element deals only with general categories of identifiers. It SHOULD not be used for codes that correspond 1..1 with the Identifier.system. Some identifiers may fall into multiple categories due to common usage. Where the system is known, a type is unnecessary because the type is always part of the system definition. However systems often need to handle identifiers where the system is not known. There is not a 1:1 relationship between type and system, since many different systems have the same type.

                                    Control0..1
                                    BindingUnless not suitable, these codes SHALL be taken from IdentifierTypeCodes
                                    (extensible to http://hl7.org/fhir/ValueSet/identifier-type)

                                    A coded type for an identifier that can be used to determine which identifier to use for a specific purpose.

                                    TypeCodeableConcept
                                    Is Modifierfalse
                                    Summarytrue
                                    Requirements

                                    Allows users to make use of identifiers when the identifier system is not known.

                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    80. MedicationRequest.groupIdentifier.system
                                    Definition

                                    Establishes the namespace for the value - that is, an absolute URL that describes a set values that are unique.

                                    ShortThe namespace for the identifier value
                                    Comments

                                    Identifier.system is always case sensitive.

                                    Control0..1
                                    Typeuri
                                    Is Modifierfalse
                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                    Summarytrue
                                    Requirements

                                    There are many sets of identifiers. To perform matching of two identifiers, we need to know what set we're dealing with. The system identifies a particular set of unique identifiers.

                                    Example<br/><b>General</b>:http://www.acme.com/identifiers/patient
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    82. MedicationRequest.groupIdentifier.value
                                    Definition

                                    The portion of the identifier typically relevant to the user and which is unique within the context of the system.

                                    ShortThe value that is unique
                                    Comments

                                    If the value is a full URI, then the system SHALL be urn:ietf:rfc:3986. The value's primary purpose is computational mapping. As a result, it may be normalized for comparison purposes (e.g. removing non-significant whitespace, dashes, etc.) A value formatted for human display can be conveyed using the http://hl7.org/fhir/StructureDefinition/rendered-value). Identifier.value is to be treated as case sensitive unless knowledge of the Identifier.system allows the processer to be confident that non-case-sensitive processing is safe.

                                    Control1..1
                                    This element is affected by the following invariants: ident-1
                                    Typestring
                                    Is Modifierfalse
                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                    Summarytrue
                                    Example<br/><b>General</b>:123456
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    84. MedicationRequest.groupIdentifier.period
                                    Definition

                                    Time period during which identifier is/was valid for use.

                                    ShortTime period when id is/was valid for use
                                    Control0..1
                                    TypePeriod
                                    Is Modifierfalse
                                    Summarytrue
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    86. MedicationRequest.groupIdentifier.assigner
                                    Definition

                                    Organization that issued/manages the identifier.

                                    ShortOrganization that issued id (may be just text)
                                    Comments

                                    The Identifier.assigner may omit the .reference element and only contain a .display element reflecting the name or other textual information about the assigning organization.

                                    Control0..1
                                    TypeReference(Organization)
                                    Is Modifierfalse
                                    Summarytrue
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    88. MedicationRequest.status
                                    Definition

                                    A code specifying the current state of the order. Generally, this will be active or completed state.

                                    ShortIndicates the status of the protocol from the prescriber's point of view
                                    Comments

                                    This element is labeled as a modifier because the status contains codes that mark the resource as not currently valid.

                                    Clinical decision support systems should take the status into account when determining which medications to include in their algorithms.

                                    Control1..1
                                    BindingThe codes SHALL be taken from MedicationrequestStatus
                                    (required to http://hl7.org/fhir/ValueSet/medicationrequest-status|5.0.0)

                                    A coded concept specifying the state of the prescribing event. Describes the lifecycle of the prescription.

                                    Typecode
                                    Is Modifiertrue because This element is labeled as a modifier because it is a status element that contains status entered-in-error which means that the resource should not be treated as valid
                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                    Must Supporttrue
                                    Summarytrue
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    90. MedicationRequest.statusReason
                                    Definition

                                    Captures the reason for the current state of the MedicationRequest.

                                    ShortReason for current status
                                    Comments

                                    This is generally only used for "exception" statuses such as "suspended" or "cancelled". The reason why the MedicationRequest was created at all is captured in reasonCode, not here.

                                    Control0..1
                                    BindingFor example codes, see MedicationRequestStatusReasonCodes
                                    (example to http://hl7.org/fhir/ValueSet/medicationrequest-status-reason)

                                    Identifies the reasons for a given status.

                                    TypeCodeableConcept
                                    Is Modifierfalse
                                    Must Supportfalse
                                    Summaryfalse
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    92. MedicationRequest.statusChanged
                                    Definition

                                    The date (and perhaps time) when the status was changed.

                                    ShortWhen the status was changed
                                    Control0..1
                                    TypedateTime
                                    Is Modifierfalse
                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                    Must Supportfalse
                                    Summaryfalse
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    94. MedicationRequest.intent
                                    Definition

                                    Whether the request is a proposal, plan, or an original order.

                                    Shortproposal | plan | order | original-order | reflex-order | filler-order | instance-order | option
                                    Comments

                                    It is expected that the type of requester will be restricted for different stages of a MedicationRequest. For example, Proposals can be created by a patient, relatedPerson, Practitioner or Device. Plans can be created by Practitioners, Patients, RelatedPersons and Devices. Original orders can be created by a Practitioner only.

                                    An instance-order is an instantiation of a request or order and may be used to populate Medication Administration Record.

                                    This element is labeled as a modifier because the intent alters when and how the resource is actually applicable.

                                    Control1..1
                                    BindingThe codes SHALL be taken from MedicationRequestIntent
                                    (required to http://hl7.org/fhir/ValueSet/medicationrequest-intent|5.0.0)

                                    The kind of medication order.

                                    Typecode
                                    Is Modifiertrue because This element changes the interpretation of all descriptive attributes. For example "the time the request is recommended to occur" vs. "the time the request is authorized to occur" or "who is recommended to perform the request" vs. "who is authorized to perform the request
                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                    Must Supportfalse
                                    Summarytrue
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    96. MedicationRequest.category
                                    Definition

                                    An arbitrary categorization or grouping of the medication request. It could be used for indicating where meds are intended to be administered, eg. in an inpatient setting or in a patient's home, or a legal category of the medication.

                                    ShortGrouping or category of medication request
                                    Comments

                                    The category can be used to include where the medication is expected to be consumed or other types of requests. The examplar value set represents where the meds are intended to be administered and is just one example of request categorization.

                                    Control0..*
                                    BindingFor example codes, see MedicationRequestAdministrationLocationCodes
                                    (example to http://hl7.org/fhir/ValueSet/medicationrequest-admin-location)

                                    A coded concept identifying where the medication is to be consumed or administered.

                                    TypeCodeableConcept
                                    Is Modifierfalse
                                    Must Supportfalse
                                    Summaryfalse
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    98. MedicationRequest.priority
                                    Definition

                                    Indicates how quickly the Medication Request should be addressed with respect to other requests.

                                    ShortAttribute indicating the urgency with which the prescription item must be completed
                                    Control0..1
                                    BindingThe codes SHALL be taken from RequestPriority
                                    (required to http://hl7.org/fhir/ValueSet/request-priority|5.0.0)

                                    Identifies the level of importance to be assigned to actioning the request.

                                    Typecode
                                    Is Modifierfalse
                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                    Must Supporttrue
                                    Summarytrue
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    100. MedicationRequest.doNotPerform
                                    Definition

                                    If true, indicates that the provider is asking for the patient to either stop taking or to not start taking the specified medication. For example, the patient is taking an existing medication and the provider is changing their medication. They want to create two seperate requests: one to stop using the current medication and another to start the new medication.

                                    ShortTrue if patient is to stop taking or not to start taking the medication
                                    Comments

                                    If do not perform is not specified, the request is a positive request e.g. "do perform".

                                    Control0..1
                                    Typeboolean
                                    Is Modifiertrue because This element is labeled as a modifier because this element negates the request to occur (ie, this is a request for the medication not to be ordered or prescribed, etc.)
                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                    Must Supportfalse
                                    Summarytrue
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    102. MedicationRequest.medication
                                    Definition

                                    Identifies the medication being requested. This is a link to a resource that represents the medication which may be the details of the medication or simply an attribute carrying a code that identifies the medication from a known list of medications.

                                    ShortMedication to be taken
                                    Comments

                                    If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the Medication resource is recommended. For example, if you require form or lot number or if the medication is compounded or extemporaneously prepared, then you must reference the Medication resource.

                                    Control1..1
                                    BindingThe codes SHALL be taken from Concepts Medication Value Set
                                    (required to http://ltsi.univ-rennes.fr/ValueSet/concept-medication-oncofair-valueset)
                                    TypeCodeableReference(Medication)
                                    Is Modifierfalse
                                    Must Supporttrue
                                    Summarytrue
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    104. MedicationRequest.medication.id
                                    Definition

                                    Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                    ShortUnique id for inter-element referencing
                                    Control0..1
                                    This element is affected by the following invariants: ele-1
                                    Typeid
                                    Is Modifierfalse
                                    XML FormatIn the XML format, this property is represented as an attribute.
                                    Summaryfalse
                                    106. MedicationRequest.medication.extension
                                    Definition

                                    May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                    ShortAdditional content defined by implementations
                                    Comments

                                    There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                    Control0..*
                                    TypeExtension
                                    Is Modifierfalse
                                    Summaryfalse
                                    Alternate Namesextensions, user content
                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                    SlicingThis element introduces a set of slices on MedicationRequest.medication.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                    • value @ url
                                    • 108. MedicationRequest.medication.concept
                                      Definition

                                      A reference to a concept - e.g. the information is identified by its general class to the degree of precision found in the terminology.

                                      ShortReference to a concept (by class)
                                      Control0..1
                                      TypeCodeableConcept
                                      Is Modifierfalse
                                      Summarytrue
                                      Pattern Value{
                                        "coding" : [{
                                          "code" : "element"
                                        }]
                                      }
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      110. MedicationRequest.medication.reference
                                      Definition

                                      A reference to a resource the provides exact details about the information being referenced.

                                      ShortReference to a resource (by instance)
                                      Control0..1
                                      TypeReference
                                      Is Modifierfalse
                                      Summarytrue
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      112. MedicationRequest.subject
                                      Definition

                                      The individual or group for whom the medication has been requested.

                                      ShortIndividual or group for whom the medication has been requested
                                      Comments

                                      The subject on a medication request is mandatory. For the secondary use case where the actual subject is not provided, there still must be an anonymized subject specified.

                                      Control1..1
                                      TypeReference(Patient, Group)
                                      Is Modifierfalse
                                      Must Supportfalse
                                      Summarytrue
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      114. MedicationRequest.informationSource
                                      Definition

                                      The person or organization who provided the information about this request, if the source is someone other than the requestor. This is often used when the MedicationRequest is reported by another person.

                                      ShortThe person or organization who provided the information about this request, if the source is someone other than the requestor
                                      Control0..*
                                      TypeReference(Patient, Practitioner, PractitionerRole, RelatedPerson, Organization)
                                      Is Modifierfalse
                                      Must Supportfalse
                                      Summaryfalse
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      116. MedicationRequest.encounter
                                      Definition

                                      The Encounter during which this [x] was created or to which the creation of this record is tightly associated.

                                      ShortEncounter created as part of encounter/admission/stay
                                      Comments

                                      This will typically be the encounter the event occurred within, but some activities may be initiated prior to or after the official completion of an encounter but still be tied to the context of the encounter." If there is a need to link to episodes of care they will be handled with an extension.

                                      Control0..1
                                      TypeReference(Encounter)
                                      Is Modifierfalse
                                      Must Supportfalse
                                      Summaryfalse
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      118. MedicationRequest.supportingInformation
                                      Definition

                                      Information to support fulfilling (i.e. dispensing or administering) of the medication, for example, patient height and weight, a MedicationStatement for the patient).

                                      ShortInformation to support fulfilling of the medication
                                      Comments

                                      This attribute can be used to reference a MedicationStatement about the patients' medication use.

                                      Control0..*
                                      TypeReference(Resource)
                                      Is Modifierfalse
                                      Must Supportfalse
                                      Summaryfalse
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      120. MedicationRequest.authoredOn
                                      Definition

                                      The date (and perhaps time) when the prescription was initially written or authored on.

                                      ShortWhen request was initially authored
                                      Control0..1
                                      TypedateTime
                                      Is Modifierfalse
                                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                      Must Supportfalse
                                      Summarytrue
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      122. MedicationRequest.requester
                                      Definition

                                      The individual, organization, or device that initiated the request and has responsibility for its activation.

                                      ShortThe requester linked to the element of prescription
                                      Control0..1
                                      TypeReference(Practitioner)
                                      Is Modifierfalse
                                      Must Supporttrue
                                      Summarytrue
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      124. MedicationRequest.reported
                                      Definition

                                      Indicates if this record was captured as a secondary 'reported' record rather than as an original primary source-of-truth record. It may also indicate the source of the report.

                                      ShortReported rather than primary record
                                      Comments

                                      If not populated, then assume that this is the original record and not reported

                                      Control0..1
                                      Typeboolean
                                      Is Modifierfalse
                                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                      Must Supportfalse
                                      Summarytrue
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      126. MedicationRequest.performerType
                                      Definition

                                      Indicates the type of performer of the administration of the medication.

                                      ShortDesired kind of performer of the medication administration
                                      Comments

                                      If specified without indicating a performer, this indicates that the performer must be of the specified type. If specified with a performer then it indicates the requirements of the performer if the designated performer is not available.

                                      Control0..1
                                      BindingUnless not suitable, these codes SHALL be taken from MedicationIntendedPerformerRole
                                      (extensible to http://hl7.org/fhir/ValueSet/medication-intended-performer-role)

                                      Identifies the type of individual that is desired to administer the medication.

                                      TypeCodeableConcept
                                      Is Modifierfalse
                                      Must Supportfalse
                                      Summarytrue
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      128. MedicationRequest.performer
                                      Definition

                                      The specified desired performer of the medication treatment (e.g. the performer of the medication administration). For devices, this is the device that is intended to perform the administration of the medication. An IV Pump would be an example of a device that is performing the administration. Both the IV Pump and the practitioner that set the rate or bolus on the pump can be listed as performers.

                                      ShortIntended performer of administration
                                      Control0..*
                                      TypeReference(Practitioner, PractitionerRole, Organization, Patient, DeviceDefinition, RelatedPerson, CareTeam, HealthcareService)
                                      Is Modifierfalse
                                      Must Supportfalse
                                      Summaryfalse
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      130. MedicationRequest.device
                                      Definition

                                      The intended type of device that is to be used for the administration of the medication (for example, PCA Pump).

                                      ShortSpecifies, where applicable, the medical devices or equipment to be used to administer the product
                                      Control0..*
                                      TypeCodeableReference(DeviceDefinition)
                                      Is Modifierfalse
                                      Must Supporttrue
                                      Summaryfalse
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      132. MedicationRequest.recorder
                                      Definition

                                      The person who entered the order on behalf of another individual for example in the case of a verbal or a telephone order.

                                      ShortPerson who entered the request
                                      Control0..1
                                      TypeReference(Practitioner, PractitionerRole)
                                      Is Modifierfalse
                                      Must Supportfalse
                                      Summaryfalse
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      134. MedicationRequest.reason
                                      Definition

                                      The reason or the indication for ordering or not ordering the medication.

                                      ShortReason or indication for ordering or not ordering the medication
                                      Comments

                                      This could be a diagnosis code. If a full condition record exists or additional detail is needed, use reasonReference.

                                      Control0..*
                                      BindingFor example codes, see ConditionProblemDiagnosisCodes
                                      (example to http://hl7.org/fhir/ValueSet/condition-code)

                                      A coded concept indicating why the medication was ordered.

                                      TypeCodeableReference(Condition, Observation)
                                      Is Modifierfalse
                                      Must Supportfalse
                                      Summaryfalse
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      136. MedicationRequest.courseOfTherapyType
                                      Definition

                                      The description of the overall pattern of the administration of the medication to the patient.

                                      ShortOverall pattern of medication administration
                                      Comments

                                      This attribute should not be confused with the protocol of the medication.

                                      Control0..1
                                      BindingUnless not suitable, these codes SHALL be taken from MedicationRequestCourseOfTherapyCodes
                                      (extensible to http://hl7.org/fhir/ValueSet/medicationrequest-course-of-therapy)

                                      Identifies the overall pattern of medication administratio.

                                      TypeCodeableConcept
                                      Is Modifierfalse
                                      Must Supportfalse
                                      Summaryfalse
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      138. MedicationRequest.insurance
                                      Definition

                                      Insurance plans, coverage extensions, pre-authorizations and/or pre-determinations that may be required for delivering the requested service.

                                      ShortAssociated insurance coverage
                                      Control0..*
                                      TypeReference(Coverage, ClaimResponse)
                                      Is Modifierfalse
                                      Must Supportfalse
                                      Summaryfalse
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      140. MedicationRequest.note
                                      Definition

                                      Extra information about the prescription that could not be conveyed by the other attributes.

                                      ShortInformation about the prescription
                                      Control0..*
                                      TypeAnnotation
                                      Is Modifierfalse
                                      Must Supporttrue
                                      Summaryfalse
                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                      SlicingThis element introduces a set of slices on MedicationRequest.note. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                      • value @ id
                                      • 142. MedicationRequest.note:wording
                                        Slice Namewording
                                        Definition

                                        Extra information about the prescription that could not be conveyed by the other attributes.

                                        ShortPrescription element wording
                                        Control0..1
                                        TypeAnnotation
                                        Is Modifierfalse
                                        Must Supportfalse
                                        Summaryfalse
                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                        144. MedicationRequest.note:wording.id
                                        Definition

                                        Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                        ShortUnique id for inter-element referencing
                                        Control1..1
                                        This element is affected by the following invariants: ele-1
                                        Typeid
                                        Is Modifierfalse
                                        XML FormatIn the XML format, this property is represented as an attribute.
                                        Summaryfalse
                                        Pattern Valuewording
                                        146. MedicationRequest.note:wording.extension
                                        Definition

                                        May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                        ShortAdditional content defined by implementations
                                        Comments

                                        There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                        Control0..*
                                        TypeExtension
                                        Is Modifierfalse
                                        Summaryfalse
                                        Alternate Namesextensions, user content
                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                        ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                        SlicingThis element introduces a set of slices on MedicationRequest.note.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                        • value @ url
                                        • 148. MedicationRequest.note:wording.author[x]
                                          Definition

                                          The individual responsible for making the annotation.

                                          ShortIndividual responsible for the annotation
                                          Comments

                                          Organization is used when there's no need for specific attribution as to who made the comment.

                                          Control0..1
                                          TypeChoice of: Reference(Practitioner, PractitionerRole, Patient, RelatedPerson, Organization), string
                                          [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                          Is Modifierfalse
                                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                          Summarytrue
                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                          150. MedicationRequest.note:wording.time
                                          Definition

                                          Indicates when this particular annotation was made.

                                          ShortWhen the annotation was made
                                          Control0..1
                                          TypedateTime
                                          Is Modifierfalse
                                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                          Summarytrue
                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                          152. MedicationRequest.note:wording.text
                                          Definition

                                          The text of the annotation in markdown format.

                                          ShortThe annotation - text content (as markdown)
                                          Control1..1
                                          Typemarkdown
                                          Is Modifierfalse
                                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                          Summarytrue
                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                          154. MedicationRequest.note:indication
                                          Slice Nameindication
                                          Definition

                                          Extra information about the prescription that could not be conveyed by the other attributes.

                                          ShortExplain the reasons that led the prescriber to prescribe this item
                                          Control0..1
                                          TypeAnnotation
                                          Is Modifierfalse
                                          Must Supportfalse
                                          Summaryfalse
                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                          156. MedicationRequest.note:indication.id
                                          Definition

                                          Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                          ShortUnique id for inter-element referencing
                                          Control1..1
                                          This element is affected by the following invariants: ele-1
                                          Typeid
                                          Is Modifierfalse
                                          XML FormatIn the XML format, this property is represented as an attribute.
                                          Summaryfalse
                                          Pattern Valueindication
                                          158. MedicationRequest.note:indication.extension
                                          Definition

                                          May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                          ShortAdditional content defined by implementations
                                          Comments

                                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                          Control0..*
                                          TypeExtension
                                          Is Modifierfalse
                                          Summaryfalse
                                          Alternate Namesextensions, user content
                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                          SlicingThis element introduces a set of slices on MedicationRequest.note.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                          • value @ url
                                          • 160. MedicationRequest.note:indication.author[x]
                                            Definition

                                            The individual responsible for making the annotation.

                                            ShortIndividual responsible for the annotation
                                            Comments

                                            Organization is used when there's no need for specific attribution as to who made the comment.

                                            Control0..1
                                            TypeChoice of: Reference(Practitioner, PractitionerRole, Patient, RelatedPerson, Organization), string
                                            [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                            Is Modifierfalse
                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                            Summarytrue
                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            162. MedicationRequest.note:indication.time
                                            Definition

                                            Indicates when this particular annotation was made.

                                            ShortWhen the annotation was made
                                            Control0..1
                                            TypedateTime
                                            Is Modifierfalse
                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                            Summarytrue
                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            164. MedicationRequest.note:indication.text
                                            Definition

                                            The text of the annotation in markdown format.

                                            ShortThe annotation - text content (as markdown)
                                            Control1..1
                                            Typemarkdown
                                            Is Modifierfalse
                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                            Summarytrue
                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            166. MedicationRequest.note:comments
                                            Slice Namecomments
                                            Definition

                                            Extra information about the prescription that could not be conveyed by the other attributes.

                                            ShortComments associated with this element, which represents the smallest entity that can be administered to the patient
                                            Control0..1
                                            TypeAnnotation
                                            Is Modifierfalse
                                            Must Supportfalse
                                            Summaryfalse
                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            168. MedicationRequest.note:comments.id
                                            Definition

                                            Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                            ShortUnique id for inter-element referencing
                                            Control1..1
                                            This element is affected by the following invariants: ele-1
                                            Typeid
                                            Is Modifierfalse
                                            XML FormatIn the XML format, this property is represented as an attribute.
                                            Summaryfalse
                                            Pattern Valuecomments
                                            170. MedicationRequest.note:comments.extension
                                            Definition

                                            May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                            ShortAdditional content defined by implementations
                                            Comments

                                            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                            Control0..*
                                            TypeExtension
                                            Is Modifierfalse
                                            Summaryfalse
                                            Alternate Namesextensions, user content
                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                            SlicingThis element introduces a set of slices on MedicationRequest.note.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                            • value @ url
                                            • 172. MedicationRequest.note:comments.author[x]
                                              Definition

                                              The individual responsible for making the annotation.

                                              ShortIndividual responsible for the annotation
                                              Comments

                                              Organization is used when there's no need for specific attribution as to who made the comment.

                                              Control0..1
                                              TypeChoice of: Reference(Practitioner, PractitionerRole, Patient, RelatedPerson, Organization), string
                                              [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                              Is Modifierfalse
                                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                              Summarytrue
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              174. MedicationRequest.note:comments.time
                                              Definition

                                              Indicates when this particular annotation was made.

                                              ShortWhen the annotation was made
                                              Control0..1
                                              TypedateTime
                                              Is Modifierfalse
                                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                              Summarytrue
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              176. MedicationRequest.note:comments.text
                                              Definition

                                              The text of the annotation in markdown format.

                                              ShortThe annotation - text content (as markdown)
                                              Control1..1
                                              Typemarkdown
                                              Is Modifierfalse
                                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                              Summarytrue
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              178. MedicationRequest.renderedDosageInstruction
                                              Definition

                                              The full representation of the dose of the medication included in all dosage instructions. To be used when multiple dosage instructions are included to represent complex dosing such as increasing or tapering doses.

                                              ShortFull representation of the dosage instructions
                                              Control0..1
                                              Typemarkdown
                                              Is Modifierfalse
                                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                              Must Supportfalse
                                              Summaryfalse
                                              Requirements

                                              The content of the renderedDosageInstructions must not be different than the dose represented in the dosageInstruction content.

                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              180. MedicationRequest.effectiveDosePeriod
                                              Definition

                                              The period over which the medication is to be taken. Where there are multiple dosageInstruction lines (for example, tapering doses), this is the earliest date and the latest end date of the dosageInstructions.

                                              ShortEffective start and end date and time of product prescription
                                              Control0..1
                                              TypePeriod
                                              Is Modifierfalse
                                              Must Supporttrue
                                              Summaryfalse
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              182. MedicationRequest.effectiveDosePeriod.id
                                              Definition

                                              Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                              ShortUnique id for inter-element referencing
                                              Control0..1
                                              This element is affected by the following invariants: ele-1
                                              Typeid
                                              Is Modifierfalse
                                              XML FormatIn the XML format, this property is represented as an attribute.
                                              Summaryfalse
                                              184. MedicationRequest.effectiveDosePeriod.extension
                                              Definition

                                              May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                              ShortAdditional content defined by implementations
                                              Comments

                                              There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                              Control0..*
                                              TypeExtension
                                              Is Modifierfalse
                                              Summaryfalse
                                              Alternate Namesextensions, user content
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                              SlicingThis element introduces a set of slices on MedicationRequest.effectiveDosePeriod.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                              • value @ url
                                              • 186. MedicationRequest.effectiveDosePeriod.start
                                                Definition

                                                The start of the period. The boundary is inclusive.

                                                ShortStarting time with inclusive boundary
                                                Comments

                                                If the low element is missing, the meaning is that the low boundary is not known.

                                                Control0..1
                                                This element is affected by the following invariants: per-1
                                                TypedateTime
                                                Is Modifierfalse
                                                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                Summarytrue
                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                188. MedicationRequest.effectiveDosePeriod.end
                                                Definition

                                                The end of the period. If the end of the period is missing, it means no end was known or planned at the time the instance was created. The start may be in the past, and the end date in the future, which means that period is expected/planned to end at that time.

                                                ShortEnd time with inclusive boundary, if not ongoing
                                                Comments

                                                The end value includes any matching date/time. i.e. 2012-02-03T10:00:00 is in a period that has an end value of 2012-02-03.

                                                Control0..1
                                                This element is affected by the following invariants: per-1
                                                TypedateTime
                                                Is Modifierfalse
                                                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                Summarytrue
                                                Meaning if MissingIf the end of the period is missing, it means that the period is ongoing
                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                190. MedicationRequest.dosageInstruction
                                                Definition

                                                Specific instructions for how the medication is to be used by the patient.

                                                ShortSpecific instructions for how the medication should be taken
                                                Comments

                                                There are examples where a medication request may include the option of an oral dose or an Intravenous or Intramuscular dose. For example, "Ondansetron 8mg orally or IV twice a day as needed for nausea" or "Compazine® (prochlorperazine) 5-10mg PO or 25mg PR bid prn nausea or vomiting". In these cases, two medication requests would be created that could be grouped together. The decision on which dose and route of administration to use is based on the patient's condition at the time the dose is needed. In general, each prescribed drug will be a separate Medication Request.

                                                When drug orders are grouped together at the time of order entry, but each of the drugs can be manipulated independently e.g. changing the status of one order to "completed" or "cancelled", changing another order status to "on-hold", the method to "group" all of the medication requests together is to use MedicationRequest.groupIdentifier element. All of the orders grouped together in this manner will have the same groupIdentifier, and separately, each order in the group may have a unique identifier.

                                                There are cases that require grouping of Medication orders together when it is necessary to specify optionality e.g. order two drugs at one time, but stating either of these drugs may be used to treat the patient. The use of a RequestOrchestration should be used as a parent for the Medication orders that require this type of grouping. An example when it may be necessary to group medication orders together is when you specify timing relationships e.g. order drug "xyz" with dose 123, then taper the same drug to a different dose after some interval of time precedence: e.g. give drug "abc" followed by drug "def" e.g. give drug 30 minutes before some procedure was performed more generically this supports - hierarchical groups of actions, where each specific action references the action to be performed (in terms of a Request resource), and each group describes additional behavior, relationships, and applicable conditions between the actions in the overall group. Note that one should NOT use the List or Composition resource to accomplish the above requirements. You may use List or Composition for other business requirements, but not to address the specific requirements of grouping medication orders.

                                                Control0..*
                                                TypeDosage
                                                Is Modifierfalse
                                                Must Supporttrue
                                                Summaryfalse
                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                • value @ id
                                                • 192. MedicationRequest.dosageInstruction:element
                                                  Slice Nameelement
                                                  Definition

                                                  Specific instructions for how the medication is to be used by the patient.

                                                  ShortSpecific instructions for how the medication should be taken
                                                  Comments

                                                  There are examples where a medication request may include the option of an oral dose or an Intravenous or Intramuscular dose. For example, "Ondansetron 8mg orally or IV twice a day as needed for nausea" or "Compazine® (prochlorperazine) 5-10mg PO or 25mg PR bid prn nausea or vomiting". In these cases, two medication requests would be created that could be grouped together. The decision on which dose and route of administration to use is based on the patient's condition at the time the dose is needed. In general, each prescribed drug will be a separate Medication Request.

                                                  When drug orders are grouped together at the time of order entry, but each of the drugs can be manipulated independently e.g. changing the status of one order to "completed" or "cancelled", changing another order status to "on-hold", the method to "group" all of the medication requests together is to use MedicationRequest.groupIdentifier element. All of the orders grouped together in this manner will have the same groupIdentifier, and separately, each order in the group may have a unique identifier.

                                                  There are cases that require grouping of Medication orders together when it is necessary to specify optionality e.g. order two drugs at one time, but stating either of these drugs may be used to treat the patient. The use of a RequestOrchestration should be used as a parent for the Medication orders that require this type of grouping. An example when it may be necessary to group medication orders together is when you specify timing relationships e.g. order drug "xyz" with dose 123, then taper the same drug to a different dose after some interval of time precedence: e.g. give drug "abc" followed by drug "def" e.g. give drug 30 minutes before some procedure was performed more generically this supports - hierarchical groups of actions, where each specific action references the action to be performed (in terms of a Request resource), and each group describes additional behavior, relationships, and applicable conditions between the actions in the overall group. Note that one should NOT use the List or Composition resource to accomplish the above requirements. You may use List or Composition for other business requirements, but not to address the specific requirements of grouping medication orders.

                                                  Control0..1
                                                  TypeDosage
                                                  Is Modifierfalse
                                                  Must Supportfalse
                                                  Summaryfalse
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  194. MedicationRequest.dosageInstruction:element.id
                                                  Definition

                                                  Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                  ShortUnique id for inter-element referencing
                                                  Control1..1
                                                  This element is affected by the following invariants: ele-1
                                                  Typeid
                                                  Is Modifierfalse
                                                  XML FormatIn the XML format, this property is represented as an attribute.
                                                  Summaryfalse
                                                  Pattern Valueelement
                                                  196. MedicationRequest.dosageInstruction:element.extension
                                                  Definition

                                                  May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                  ShortAdditional content defined by implementations
                                                  Comments

                                                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                  Control0..*
                                                  TypeExtension
                                                  Is Modifierfalse
                                                  Summaryfalse
                                                  Alternate Namesextensions, user content
                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                  SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                  • value @ url
                                                  • 198. MedicationRequest.dosageInstruction:element.modifierExtension
                                                    Definition

                                                    May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                    Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                    ShortExtensions that cannot be ignored even if unrecognized
                                                    Comments

                                                    There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                    Control0..*
                                                    TypeExtension
                                                    Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                    Summarytrue
                                                    Requirements

                                                    Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                    Alternate Namesextensions, user content, modifiers
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                    200. MedicationRequest.dosageInstruction:element.sequence
                                                    Definition

                                                    Indicates the order in which the dosage instructions should be applied or interpreted.

                                                    ShortThe order of the dosage instructions
                                                    Control0..1
                                                    Typeinteger
                                                    Is Modifierfalse
                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                    Summarytrue
                                                    Requirements

                                                    If the sequence number of multiple Dosages is the same, then it is implied that the instructions are to be treated as concurrent. If the sequence number is different, then the Dosages are intended to be sequential.

                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    202. MedicationRequest.dosageInstruction:element.text
                                                    Definition

                                                    Free text dosage instructions e.g. SIG.

                                                    ShortDescription of the prescribed dosage, in text form.
                                                    Control0..1
                                                    Typestring
                                                    Is Modifierfalse
                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                    Summarytrue
                                                    Requirements

                                                    Free text dosage instructions can be used for cases where the instructions are too complex to code. The content of this attribute does not include the name or description of the medication. When coded instructions are present, the free text instructions may still be present for display to humans taking or administering the medication. It is expected that the text instructions will always be populated. If the dosage.timing attribute is also populated, then the dosage.text should reflect the same information as the timing. Additional information about administration or preparation of the medication should be included as text.

                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    204. MedicationRequest.dosageInstruction:element.additionalInstruction
                                                    Definition

                                                    Supplemental instructions to the patient on how to take the medication (e.g. "with meals" or"take half to one hour before food") or warnings for the patient about the medication (e.g. "may cause drowsiness" or "avoid exposure of skin to direct sunlight or sunlamps").

                                                    ShortFree text describing the conditions of application of this prescription element
                                                    Comments

                                                    Information about administration or preparation of the medication (e.g. "infuse as rapidly as possibly via intraperitoneal port" or take "immediately following drug x") should be populated in dosage.text.

                                                    Control0..1
                                                    BindingFor example codes, see SNOMEDCTAdditionalDosageInstructions
                                                    (example to http://hl7.org/fhir/ValueSet/additional-instruction-codes)

                                                    A coded concept identifying additional instructions such as "take with water" or "avoid operating heavy machinery".

                                                    TypeCodeableConcept
                                                    Is Modifierfalse
                                                    Summarytrue
                                                    Requirements

                                                    Additional instruction is intended to be coded, but where no code exists, the element could include text. For example, "Swallow with plenty of water" which might or might not be coded.

                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    206. MedicationRequest.dosageInstruction:element.patientInstruction
                                                    Definition

                                                    Instructions in terms that are understood by the patient or consumer.

                                                    ShortPatient or consumer oriented instructions
                                                    Control0..1
                                                    Typestring
                                                    Is Modifierfalse
                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                    Summarytrue
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    208. MedicationRequest.dosageInstruction:element.timing
                                                    Definition

                                                    When medication should be administered.

                                                    ShortWhen medication should be administered
                                                    Comments

                                                    This attribute might not always be populated while the Dosage.text is expected to be populated. If both are populated, then the Dosage.text should reflect the content of the Dosage.timing.

                                                    Control0..1
                                                    TypeTiming
                                                    Is Modifierfalse
                                                    Summarytrue
                                                    Requirements

                                                    The timing schedule for giving the medication to the patient. This data type allows many different expressions. For example: "Every 8 hours"; "Three times a day"; "1/2 an hour before breakfast for 10 days from 23-Dec 2011:"; "15 Oct 2013, 17 Oct 2013 and 1 Nov 2013". Sometimes, a rate can imply duration when expressed as total volume / duration (e.g. 500mL/2 hours implies a duration of 2 hours). However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period.

                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    210. MedicationRequest.dosageInstruction:element.timing.id
                                                    Definition

                                                    Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                    ShortUnique id for inter-element referencing
                                                    Control0..1
                                                    This element is affected by the following invariants: ele-1
                                                    Typeid
                                                    Is Modifierfalse
                                                    XML FormatIn the XML format, this property is represented as an attribute.
                                                    Summaryfalse
                                                    212. MedicationRequest.dosageInstruction:element.timing.extension
                                                    Definition

                                                    May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                    ShortAdditional content defined by implementations
                                                    Comments

                                                    There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                    Control0..*
                                                    TypeExtension
                                                    Is Modifierfalse
                                                    Summaryfalse
                                                    Alternate Namesextensions, user content
                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                    SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction.timing.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                    • value @ url
                                                    • 214. MedicationRequest.dosageInstruction:element.timing.modifierExtension
                                                      Definition

                                                      May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                      Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                      ShortExtensions that cannot be ignored even if unrecognized
                                                      Comments

                                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                      Control0..*
                                                      TypeExtension
                                                      Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                      Summarytrue
                                                      Requirements

                                                      Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                      Alternate Namesextensions, user content, modifiers
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                      216. MedicationRequest.dosageInstruction:element.timing.event
                                                      Definition

                                                      Identifies specific times when the event occurs.

                                                      ShortWhen the event occurs
                                                      Control0..*
                                                      TypedateTime
                                                      Is Modifierfalse
                                                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                      Summarytrue
                                                      Requirements

                                                      In a Medication Administration Record, for instance, you need to take a general specification, and turn it into a precise specification.

                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      218. MedicationRequest.dosageInstruction:element.timing.repeat
                                                      Definition

                                                      A set of rules that describe when the event is scheduled.

                                                      ShortWhen the event is to occur
                                                      Control0..1
                                                      TypeElement
                                                      Is Modifierfalse
                                                      Summarytrue
                                                      Requirements

                                                      Many timing schedules are determined by regular repetitions.

                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      tim-1: if there's a duration, there needs to be duration units (duration.empty() or durationUnit.exists())
                                                      tim-2: if there's a period, there needs to be period units (period.empty() or periodUnit.exists())
                                                      tim-4: duration SHALL be a non-negative value (duration.exists() implies duration >= 0)
                                                      tim-5: period SHALL be a non-negative value (period.exists() implies period >= 0)
                                                      tim-6: If there's a periodMax, there must be a period (periodMax.empty() or period.exists())
                                                      tim-7: If there's a durationMax, there must be a duration (durationMax.empty() or duration.exists())
                                                      tim-8: If there's a countMax, there must be a count (countMax.empty() or count.exists())
                                                      tim-9: If there's an offset, there must be a when (and not C, CM, CD, CV) (offset.empty() or (when.exists() and when.select($this in ('C' | 'CM' | 'CD' | 'CV')).allFalse()))
                                                      tim-10: If there's a timeOfDay, there cannot be a when, or vice versa (timeOfDay.empty() or when.empty())
                                                      220. MedicationRequest.dosageInstruction:element.timing.repeat.id
                                                      Definition

                                                      Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                      ShortUnique id for inter-element referencing
                                                      Control0..1
                                                      This element is affected by the following invariants: ele-1
                                                      Typestring
                                                      Is Modifierfalse
                                                      XML FormatIn the XML format, this property is represented as an attribute.
                                                      Summaryfalse
                                                      222. MedicationRequest.dosageInstruction:element.timing.repeat.extension
                                                      Definition

                                                      May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                      ShortAdditional content defined by implementations
                                                      Comments

                                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                      Control0..*
                                                      TypeExtension
                                                      Is Modifierfalse
                                                      Summaryfalse
                                                      Alternate Namesextensions, user content
                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                      SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction.timing.repeat.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                      • value @ url
                                                      • 224. MedicationRequest.dosageInstruction:element.timing.repeat.bounds[x]
                                                        Definition

                                                        Either a duration for the length of the timing schedule, a range of possible length, or outer bounds for start and/or end limits of the timing schedule.

                                                        ShortLength/Range of lengths, or (Start and/or end) limits
                                                        Control0..1
                                                        TypeChoice of: Duration, Range, Period
                                                        [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                        Is Modifierfalse
                                                        Summarytrue
                                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                        SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction.timing.repeat.bounds[x]. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                        • type @ $this
                                                        • 226. MedicationRequest.dosageInstruction:element.timing.repeat.bounds[x]:boundsPeriod
                                                          Slice NameboundsPeriod
                                                          Definition

                                                          Either a duration for the length of the timing schedule, a range of possible length, or outer bounds for start and/or end limits of the timing schedule.

                                                          ShortLength/Range of lengths, or (Start and/or end) limits
                                                          Control0..1
                                                          TypePeriod
                                                          [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                          Is Modifierfalse
                                                          Summarytrue
                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                          228. MedicationRequest.dosageInstruction:element.timing.repeat.bounds[x]:boundsPeriod.id
                                                          Definition

                                                          Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                          ShortUnique id for inter-element referencing
                                                          Control0..1
                                                          This element is affected by the following invariants: ele-1
                                                          Typeid
                                                          Is Modifierfalse
                                                          XML FormatIn the XML format, this property is represented as an attribute.
                                                          Summaryfalse
                                                          230. MedicationRequest.dosageInstruction:element.timing.repeat.bounds[x]:boundsPeriod.extension
                                                          Definition

                                                          May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                          ShortAdditional content defined by implementations
                                                          Comments

                                                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                          Control0..*
                                                          TypeExtension
                                                          Is Modifierfalse
                                                          Summaryfalse
                                                          Alternate Namesextensions, user content
                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                          SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction.timing.repeat.bounds[x].extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                          • value @ url
                                                          • 232. MedicationRequest.dosageInstruction:element.timing.repeat.bounds[x]:boundsPeriod.start
                                                            Definition

                                                            The start of the period. The boundary is inclusive.

                                                            ShortPrescribed start date and time of product prescription
                                                            Comments

                                                            If the low element is missing, the meaning is that the low boundary is not known.

                                                            Control0..1
                                                            This element is affected by the following invariants: per-1
                                                            TypedateTime
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            234. MedicationRequest.dosageInstruction:element.timing.repeat.bounds[x]:boundsPeriod.end
                                                            Definition

                                                            The end of the period. If the end of the period is missing, it means no end was known or planned at the time the instance was created. The start may be in the past, and the end date in the future, which means that period is expected/planned to end at that time.

                                                            ShortPrescribed end date and time of product prescription
                                                            Comments

                                                            The end value includes any matching date/time. i.e. 2012-02-03T10:00:00 is in a period that has an end value of 2012-02-03.

                                                            Control0..1
                                                            This element is affected by the following invariants: per-1
                                                            TypedateTime
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Meaning if MissingIf the end of the period is missing, it means that the period is ongoing
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            236. MedicationRequest.dosageInstruction:element.timing.repeat.count
                                                            Definition

                                                            A total count of the desired number of repetitions across the duration of the entire timing specification. If countMax is present, this element indicates the lower bound of the allowed range of count values.

                                                            ShortNumber of times to repeat
                                                            Comments

                                                            If you have both bounds and count, then this should be understood as within the bounds period, until count times happens.

                                                            Control0..1
                                                            This element is affected by the following invariants: tim-8
                                                            TypepositiveInt
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Requirements

                                                            Repetitions may be limited by end time or total occurrences.

                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            238. MedicationRequest.dosageInstruction:element.timing.repeat.countMax
                                                            Definition

                                                            If present, indicates that the count is a range - so to perform the action between [count] and [countMax] times.

                                                            ShortMaximum number of times to repeat
                                                            Control0..1
                                                            This element is affected by the following invariants: tim-8
                                                            TypepositiveInt
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            240. MedicationRequest.dosageInstruction:element.timing.repeat.duration
                                                            Definition

                                                            How long this thing happens for when it happens. If durationMax is present, this element indicates the lower bound of the allowed range of the duration.

                                                            ShortHow long when it happens
                                                            Comments

                                                            For some events the duration is part of the definition of the event (e.g. IV infusions, where the duration is implicit in the specified quantity and rate). For others, it's part of the timing specification (e.g. exercise).

                                                            Control0..1
                                                            This element is affected by the following invariants: tim-7, tim-1, tim-4
                                                            Typedecimal
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Requirements

                                                            Some activities are not instantaneous and need to be maintained for a period of time.

                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            242. MedicationRequest.dosageInstruction:element.timing.repeat.durationMax
                                                            Definition

                                                            If present, indicates that the duration is a range - so to perform the action between [duration] and [durationMax] time length.

                                                            ShortHow long when it happens (Max)
                                                            Comments

                                                            For some events the duration is part of the definition of the event (e.g. IV infusions, where the duration is implicit in the specified quantity and rate). For others, it's part of the timing specification (e.g. exercise).

                                                            Control0..1
                                                            This element is affected by the following invariants: tim-7
                                                            Typedecimal
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Requirements

                                                            Some activities are not instantaneous and need to be maintained for a period of time.

                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            244. MedicationRequest.dosageInstruction:element.timing.repeat.durationUnit
                                                            Definition

                                                            The units of time for the duration, in UCUM units Normal practice is to use the 'mo' code as a calendar month when calculating the next occurrence.

                                                            Shorts | min | h | d | wk | mo | a - unit of time (UCUM)
                                                            Control0..1
                                                            This element is affected by the following invariants: tim-1
                                                            BindingThe codes SHALL be taken from UnitsOfTime
                                                            (required to http://hl7.org/fhir/ValueSet/units-of-time|5.0.0)

                                                            A unit of time (units from UCUM).

                                                            Typecode
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            246. MedicationRequest.dosageInstruction:element.timing.repeat.frequency
                                                            Definition

                                                            The number of times to repeat the action within the specified period. If frequencyMax is present, this element indicates the lower bound of the allowed range of the frequency.

                                                            ShortIndicates the number of repetitions that should occur within a period. I.e. Event occurs frequency times per period
                                                            Control0..1
                                                            TypepositiveInt
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Meaning if MissingIf no frequency is stated, the assumption is that the event occurs once per period, but systems SHOULD always be specific about this
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            248. MedicationRequest.dosageInstruction:element.timing.repeat.frequencyMax
                                                            Definition

                                                            If present, indicates that the frequency is a range - so to repeat between [frequency] and [frequencyMax] times within the period or period range.

                                                            ShortEvent occurs up to frequencyMax times per period
                                                            Control0..1
                                                            TypepositiveInt
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            250. MedicationRequest.dosageInstruction:element.timing.repeat.period
                                                            Definition

                                                            Indicates the duration of time over which repetitions are to occur; e.g. to express "3 times per day", 3 would be the frequency and "1 day" would be the period. If periodMax is present, this element indicates the lower bound of the allowed range of the period length.

                                                            ShortThe duration to which the frequency applies. I.e. Event occurs frequency times per period
                                                            Control0..1
                                                            This element is affected by the following invariants: tim-6, tim-5, tim-2
                                                            Typedecimal
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            252. MedicationRequest.dosageInstruction:element.timing.repeat.periodMax
                                                            Definition

                                                            If present, indicates that the period is a range from [period] to [periodMax], allowing expressing concepts such as "do this once every 3-5 days.

                                                            ShortUpper limit of period (3-4 hours)
                                                            Control0..1
                                                            This element is affected by the following invariants: tim-6
                                                            Typedecimal
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            254. MedicationRequest.dosageInstruction:element.timing.repeat.periodUnit
                                                            Definition

                                                            The units of time for the period in UCUM units Normal practice is to use the 'mo' code as a calendar month when calculating the next occurrence.

                                                            Shorts | min | h | d | wk | mo | a - unit of time (UCUM)
                                                            Control0..1
                                                            This element is affected by the following invariants: tim-2
                                                            BindingThe codes SHALL be taken from UnitsOfTime
                                                            (required to http://hl7.org/fhir/ValueSet/units-of-time|5.0.0)

                                                            A unit of time (units from UCUM).

                                                            Typecode
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            256. MedicationRequest.dosageInstruction:element.timing.repeat.dayOfWeek
                                                            Definition

                                                            If one or more days of week is provided, then the action happens only on the specified day(s).

                                                            Shortmon | tue | wed | thu | fri | sat | sun
                                                            Comments

                                                            If no days are specified, the action is assumed to happen every day as otherwise specified.

                                                            Control0..*
                                                            BindingThe codes SHALL be taken from DaysOfWeek
                                                            (required to http://hl7.org/fhir/ValueSet/days-of-week|5.0.0)
                                                            Typecode
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            258. MedicationRequest.dosageInstruction:element.timing.repeat.timeOfDay
                                                            Definition

                                                            Specified time of day for action to take place.

                                                            ShortTime of day for action
                                                            Comments

                                                            When time of day is specified, it is inferred that the action happens every day (as filtered by dayofWeek) on the specified times. If there's a timeOfDay, there cannot be a when, or vice versa.

                                                            Control0..*
                                                            This element is affected by the following invariants: tim-10
                                                            Typetime
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            260. MedicationRequest.dosageInstruction:element.timing.repeat.when
                                                            Definition

                                                            An approximate time period during the day, potentially linked to an event of daily living that indicates when the action should occur.

                                                            ShortCode for time period of occurrence
                                                            Comments

                                                            When more than one event is listed, the event is tied to the union of the specified events.

                                                            Control0..*
                                                            This element is affected by the following invariants: tim-9, tim-10
                                                            BindingThe codes SHALL be taken from EventTiming
                                                            (required to http://hl7.org/fhir/ValueSet/event-timing|5.0.0)

                                                            Real-world event relating to the schedule.

                                                            Typecode
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Requirements

                                                            Timings are frequently determined by occurrences such as waking, eating and sleep.

                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            262. MedicationRequest.dosageInstruction:element.timing.repeat.offset
                                                            Definition

                                                            The number of minutes from the event. If the event code does not indicate whether the minutes is before or after the event, then the offset is assumed to be after the event.

                                                            ShortDecimal value, positive or negative, of the interval between the reference date/time of the prescribed protocol and that of this prescription item
                                                            Control0..1
                                                            This element is affected by the following invariants: tim-9
                                                            TypeunsignedInt
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            264. MedicationRequest.dosageInstruction:element.timing.code
                                                            Definition

                                                            A code for the timing schedule (or just text in code.text). Some codes such as BID are ubiquitous, but many institutions define their own additional codes. If a code is provided, the code is understood to be a complete statement of whatever is specified in the structured timing data, and either the code or the data may be used to interpret the Timing, with the exception that .repeat.bounds still applies over the code (and is not contained in the code).

                                                            ShortC | BID | TID | QID | AM | PM | QD | QOD | +
                                                            Comments

                                                            BID etc. are defined as 'at institutionally specified times'. For example, an institution may choose that BID is "always at 7am and 6pm". If it is inappropriate for this choice to be made, the code BID should not be used. Instead, a distinct organization-specific code should be used in place of the HL7-defined BID code and/or a structured representation should be used (in this case, specifying the two event times).

                                                            Control0..1
                                                            BindingThe codes SHOULD be taken from TimingAbbreviation
                                                            (preferred to http://hl7.org/fhir/ValueSet/timing-abbreviation)

                                                            Code for a known / defined timing pattern.

                                                            TypeCodeableConcept
                                                            Is Modifierfalse
                                                            Summarytrue
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            266. MedicationRequest.dosageInstruction:element.asNeeded
                                                            Definition

                                                            Indicates whether the Medication is only taken when needed within a specific dosing schedule (Boolean option).

                                                            ShortTake "as needed"
                                                            Comments

                                                            Can express "as needed" without a reason by setting the Boolean = True. In this case the CodeableConcept is not populated.

                                                            Control0..1
                                                            This element is affected by the following invariants: dos-1
                                                            Typeboolean
                                                            Is Modifierfalse
                                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                            Summarytrue
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            268. MedicationRequest.dosageInstruction:element.asNeededFor
                                                            Definition

                                                            Indicates whether the Medication is only taken based on a precondition for taking the Medication (CodeableConcept).

                                                            ShortTake "as needed" (for x)
                                                            Comments

                                                            Can express "as needed" with a reason by including the CodeableConcept. In this case the Boolean is assumed to be False, then the dose is given according to the schedule and is not "prn" or "as needed".

                                                            Control0..*
                                                            This element is affected by the following invariants: dos-1
                                                            BindingFor example codes, see SNOMEDCTMedicationAsNeededReasonCodes
                                                            (example to http://hl7.org/fhir/ValueSet/medication-as-needed-reason)

                                                            A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc.

                                                            TypeCodeableConcept
                                                            Is Modifierfalse
                                                            Summarytrue
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            270. MedicationRequest.dosageInstruction:element.site
                                                            Definition

                                                            Body site to administer to.

                                                            ShortSpecifies, where appropriate, the exact point on the body where the product is to be applied to the patient
                                                            Comments

                                                            If the use case requires attributes from the BodySite resource (e.g. to identify and track separately) then use the standard extension http://hl7.org/fhir/StructureDefinition/bodySite. May be a summary code, or a reference to a very precise definition of the location, or both.

                                                            Control0..1
                                                            BindingFor example codes, see SNOMEDCTAnatomicalStructureAdministrationSites
                                                            (example to http://hl7.org/fhir/ValueSet/approach-site-codes)

                                                            A coded concept describing the site location the medicine enters into or onto the body.

                                                            TypeCodeableConcept
                                                            Is Modifierfalse
                                                            Summarytrue
                                                            Requirements

                                                            A coded specification of the anatomic site where the medication first enters the body.

                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            272. MedicationRequest.dosageInstruction:element.route
                                                            Definition

                                                            How drug should enter body.

                                                            ShortSpecifies the route of administration of the product
                                                            Control0..1
                                                            BindingFor example codes, see SNOMEDCTRouteCodes
                                                            (example to http://hl7.org/fhir/ValueSet/route-codes)

                                                            A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.

                                                            TypeCodeableConcept
                                                            Is Modifierfalse
                                                            Summarytrue
                                                            Requirements

                                                            A code specifying the route or physiological path of administration of a therapeutic agent into or onto a patient's body.

                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            274. MedicationRequest.dosageInstruction:element.method
                                                            Definition

                                                            Technique for administering medication.

                                                            ShortType of prescription element
                                                            Comments

                                                            Terminologies used often pre-coordinate this term with the route and or form of administration.

                                                            Control0..1
                                                            BindingThe codes SHALL be taken from Type de l'élément d'administration Value Set
                                                            (required to http://ltsi.univ-rennes.fr/ValueSet/siph-typeeltpla-oncofair-valueset)
                                                            TypeCodeableConcept
                                                            Is Modifierfalse
                                                            Summarytrue
                                                            Requirements

                                                            A coded value indicating the method by which the medication is introduced into or onto the body. Most commonly used for injections. For examples, Slow Push; Deep IV.

                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            276. MedicationRequest.dosageInstruction:element.doseAndRate
                                                            Definition

                                                            Depending on the resource,this is the amount of medication administered, to be administered or typical amount to be administered.

                                                            ShortAmount of medication administered, to be administered or typical amount to be administered
                                                            Control0..*
                                                            TypeElement
                                                            Is Modifierfalse
                                                            Summarytrue
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            278. MedicationRequest.dosageInstruction:element.doseAndRate.id
                                                            Definition

                                                            Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                            ShortUnique id for inter-element referencing
                                                            Control0..1
                                                            This element is affected by the following invariants: ele-1
                                                            Typestring
                                                            Is Modifierfalse
                                                            XML FormatIn the XML format, this property is represented as an attribute.
                                                            Summaryfalse
                                                            280. MedicationRequest.dosageInstruction:element.doseAndRate.extension
                                                            Definition

                                                            May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                            ShortAdditional content defined by implementations
                                                            Comments

                                                            There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                            Control0..*
                                                            TypeExtension
                                                            Is Modifierfalse
                                                            Summaryfalse
                                                            Alternate Namesextensions, user content
                                                            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                            SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction.doseAndRate.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                            • value @ url
                                                            • 282. MedicationRequest.dosageInstruction:element.doseAndRate.type
                                                              Definition

                                                              The kind of dose or rate specified, for example, ordered or calculated.

                                                              ShortThe kind of dose or rate specified
                                                              Control0..1
                                                              BindingFor example codes, see DoseAndRateType
                                                              (example to http://terminology.hl7.org/ValueSet/dose-rate-type)

                                                              The kind of dose or rate specified.

                                                              TypeCodeableConcept
                                                              Is Modifierfalse
                                                              Summarytrue
                                                              Requirements

                                                              If the type is not populated, assume to be "ordered".

                                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                              284. MedicationRequest.dosageInstruction:element.doseAndRate.dose[x]
                                                              Definition

                                                              Amount of medication per dose.

                                                              ShortAmount of medication per dose
                                                              Comments

                                                              Note that this specifies the quantity of the specified medication, not the quantity for each active ingredient(s). Each ingredient amount can be communicated in the Medication resource. For example, if one wants to communicate that a tablet was 375 mg, where the dose was one tablet, you can use the Medication resource to document that the tablet was comprised of 375 mg of drug XYZ. Alternatively if the dose was 375 mg, then you may only need to use the Medication resource to indicate this was a tablet. If the example were an IV such as dopamine and you wanted to communicate that 400mg of dopamine was mixed in 500 ml of some IV solution, then this would all be communicated in the Medication resource. If the administration is not intended to be instantaneous (rate is present or timing has a duration), this can be specified to convey the total amount to be administered over the period of time as indicated by the schedule e.g. 500 ml in dose, with timing used to convey that this should be done over 4 hours.

                                                              Control0..1
                                                              TypeChoice of: Range, Quantity(SimpleQuantity)
                                                              [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                              Is Modifierfalse
                                                              Summarytrue
                                                              Requirements

                                                              The amount of therapeutic or other substance given at one administration event.

                                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                              286. MedicationRequest.dosageInstruction:element.doseAndRate.rate[x]
                                                              Definition

                                                              Amount of medication per unit of time.

                                                              ShortAmount of medication per unit of time
                                                              Comments

                                                              It is possible to supply both a rate and a doseQuantity to provide full details about how the medication is to be administered and supplied. If the rate is intended to change over time, depending on local rules/regulations, each change should be captured as a new version of the MedicationRequest with an updated rate, or captured with a new MedicationRequest with the new rate.

                                                              It is possible to specify a rate over time (for example, 100 ml/hour) using either the rateRatio and rateQuantity. The rateQuantity approach requires systems to have the capability to parse UCUM grammar where ml/hour is included rather than a specific ratio where the time is specified as the denominator. Where a rate such as 500ml over 2 hours is specified, the use of rateRatio may be more semantically correct than specifying using a rateQuantity of 250 mg/hour.

                                                              Control0..1
                                                              TypeChoice of: Ratio, Range, Quantity(SimpleQuantity)
                                                              [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                              Is Modifierfalse
                                                              Summarytrue
                                                              Requirements

                                                              Identifies the speed with which the medication was or will be introduced into the patient. Typically the rate for an infusion e.g. 100 ml per 1 hour or 100 ml/hr. May also be expressed as a rate per unit of time e.g. 500 ml per 2 hours. Other examples: 200 mcg/min or 200 mcg/1 minute; 1 liter/8 hours. Sometimes, a rate can imply duration when expressed as total volume / duration (e.g. 500mL/2 hours implies a duration of 2 hours). However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period.

                                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                              288. MedicationRequest.dosageInstruction:element.maxDosePerPeriod
                                                              Definition

                                                              Upper limit on medication per unit of time.

                                                              ShortUpper limit on medication per unit of time
                                                              Comments

                                                              This is intended for use as an adjunct to the dosage when there is an upper cap. For example "2 tablets every 4 hours to a maximum of 8/day".

                                                              Control0..*
                                                              TypeRatio
                                                              Is Modifierfalse
                                                              Summarytrue
                                                              Requirements

                                                              The maximum total quantity of a therapeutic substance that may be administered to a subject over the period of time. For example, 1000mg in 24 hours.

                                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                              290. MedicationRequest.dosageInstruction:element.maxDosePerAdministration
                                                              Definition

                                                              Upper limit on medication per administration.

                                                              ShortUpper limit on medication per administration
                                                              Comments

                                                              This is intended for use as an adjunct to the dosage when there is an upper cap. For example, a body surface area related dose with a maximum amount, such as 1.5 mg/m2 (maximum 2 mg) IV over 5 – 10 minutes would have doseQuantity of 1.5 mg/m2 and maxDosePerAdministration of 2 mg.

                                                              Control0..1
                                                              TypeQuantity(SimpleQuantity)
                                                              Is Modifierfalse
                                                              Summarytrue
                                                              Requirements

                                                              The maximum total quantity of a therapeutic substance that may be administered to a subject per administration.

                                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                              292. MedicationRequest.dosageInstruction:element.maxDosePerLifetime
                                                              Definition

                                                              Upper limit on medication per lifetime of the patient.

                                                              ShortUpper limit on medication per lifetime of the patient
                                                              Control0..1
                                                              TypeQuantity(SimpleQuantity)
                                                              Is Modifierfalse
                                                              Summarytrue
                                                              Requirements

                                                              The maximum total quantity of a therapeutic substance that may be administered per lifetime of the subject.

                                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                              294. MedicationRequest.dosageInstruction:posology
                                                              Slice Nameposology
                                                              Definition

                                                              Specific instructions for how the medication is to be used by the patient.

                                                              ShortSpecific instructions for how the medication should be taken
                                                              Comments

                                                              There are examples where a medication request may include the option of an oral dose or an Intravenous or Intramuscular dose. For example, "Ondansetron 8mg orally or IV twice a day as needed for nausea" or "Compazine® (prochlorperazine) 5-10mg PO or 25mg PR bid prn nausea or vomiting". In these cases, two medication requests would be created that could be grouped together. The decision on which dose and route of administration to use is based on the patient's condition at the time the dose is needed. In general, each prescribed drug will be a separate Medication Request.

                                                              When drug orders are grouped together at the time of order entry, but each of the drugs can be manipulated independently e.g. changing the status of one order to "completed" or "cancelled", changing another order status to "on-hold", the method to "group" all of the medication requests together is to use MedicationRequest.groupIdentifier element. All of the orders grouped together in this manner will have the same groupIdentifier, and separately, each order in the group may have a unique identifier.

                                                              There are cases that require grouping of Medication orders together when it is necessary to specify optionality e.g. order two drugs at one time, but stating either of these drugs may be used to treat the patient. The use of a RequestOrchestration should be used as a parent for the Medication orders that require this type of grouping. An example when it may be necessary to group medication orders together is when you specify timing relationships e.g. order drug "xyz" with dose 123, then taper the same drug to a different dose after some interval of time precedence: e.g. give drug "abc" followed by drug "def" e.g. give drug 30 minutes before some procedure was performed more generically this supports - hierarchical groups of actions, where each specific action references the action to be performed (in terms of a Request resource), and each group describes additional behavior, relationships, and applicable conditions between the actions in the overall group. Note that one should NOT use the List or Composition resource to accomplish the above requirements. You may use List or Composition for other business requirements, but not to address the specific requirements of grouping medication orders.

                                                              Control0..*
                                                              TypeDosage
                                                              Is Modifierfalse
                                                              Must Supportfalse
                                                              Summaryfalse
                                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                              296. MedicationRequest.dosageInstruction:posology.id
                                                              Definition

                                                              Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                              ShortUnique id for inter-element referencing
                                                              Control1..1
                                                              This element is affected by the following invariants: ele-1
                                                              Typeid
                                                              Is Modifierfalse
                                                              XML FormatIn the XML format, this property is represented as an attribute.
                                                              Summaryfalse
                                                              Pattern Valueposology
                                                              298. MedicationRequest.dosageInstruction:posology.extension
                                                              Definition

                                                              May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                              ShortAdditional content defined by implementations
                                                              Comments

                                                              There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                              Control0..*
                                                              TypeExtension
                                                              Is Modifierfalse
                                                              Summaryfalse
                                                              Alternate Namesextensions, user content
                                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                              SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                              • value @ url
                                                              • 300. MedicationRequest.dosageInstruction:posology.modifierExtension
                                                                Definition

                                                                May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                                Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                                ShortExtensions that cannot be ignored even if unrecognized
                                                                Comments

                                                                There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                Control0..*
                                                                TypeExtension
                                                                Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                                Summarytrue
                                                                Requirements

                                                                Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                                Alternate Namesextensions, user content, modifiers
                                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                302. MedicationRequest.dosageInstruction:posology.sequence
                                                                Definition

                                                                Indicates the order in which the dosage instructions should be applied or interpreted.

                                                                ShortThe order of the dosage instructions
                                                                Control0..1
                                                                Typeinteger
                                                                Is Modifierfalse
                                                                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                Summarytrue
                                                                Requirements

                                                                If the sequence number of multiple Dosages is the same, then it is implied that the instructions are to be treated as concurrent. If the sequence number is different, then the Dosages are intended to be sequential.

                                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                304. MedicationRequest.dosageInstruction:posology.text
                                                                Definition

                                                                Free text dosage instructions e.g. SIG.

                                                                ShortFree text dosage instructions e.g. SIG
                                                                Control0..1
                                                                Typestring
                                                                Is Modifierfalse
                                                                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                Summarytrue
                                                                Requirements

                                                                Free text dosage instructions can be used for cases where the instructions are too complex to code. The content of this attribute does not include the name or description of the medication. When coded instructions are present, the free text instructions may still be present for display to humans taking or administering the medication. It is expected that the text instructions will always be populated. If the dosage.timing attribute is also populated, then the dosage.text should reflect the same information as the timing. Additional information about administration or preparation of the medication should be included as text.

                                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                306. MedicationRequest.dosageInstruction:posology.additionalInstruction
                                                                Definition

                                                                Supplemental instructions to the patient on how to take the medication (e.g. "with meals" or"take half to one hour before food") or warnings for the patient about the medication (e.g. "may cause drowsiness" or "avoid exposure of skin to direct sunlight or sunlamps").

                                                                ShortSupplemental instruction or warnings to the patient - e.g. "with meals", "may cause drowsiness"
                                                                Comments

                                                                Information about administration or preparation of the medication (e.g. "infuse as rapidly as possibly via intraperitoneal port" or take "immediately following drug x") should be populated in dosage.text.

                                                                Control0..*
                                                                BindingFor example codes, see SNOMEDCTAdditionalDosageInstructions
                                                                (example to http://hl7.org/fhir/ValueSet/additional-instruction-codes)

                                                                A coded concept identifying additional instructions such as "take with water" or "avoid operating heavy machinery".

                                                                TypeCodeableConcept
                                                                Is Modifierfalse
                                                                Summarytrue
                                                                Requirements

                                                                Additional instruction is intended to be coded, but where no code exists, the element could include text. For example, "Swallow with plenty of water" which might or might not be coded.

                                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                308. MedicationRequest.dosageInstruction:posology.patientInstruction
                                                                Definition

                                                                Instructions in terms that are understood by the patient or consumer.

                                                                ShortPatient or consumer oriented instructions
                                                                Control0..1
                                                                Typestring
                                                                Is Modifierfalse
                                                                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                Summarytrue
                                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                310. MedicationRequest.dosageInstruction:posology.timing
                                                                Definition

                                                                When medication should be administered.

                                                                ShortWhen medication should be administered
                                                                Comments

                                                                This attribute might not always be populated while the Dosage.text is expected to be populated. If both are populated, then the Dosage.text should reflect the content of the Dosage.timing.

                                                                Control0..1
                                                                TypeTiming
                                                                Is Modifierfalse
                                                                Summarytrue
                                                                Requirements

                                                                The timing schedule for giving the medication to the patient. This data type allows many different expressions. For example: "Every 8 hours"; "Three times a day"; "1/2 an hour before breakfast for 10 days from 23-Dec 2011:"; "15 Oct 2013, 17 Oct 2013 and 1 Nov 2013". Sometimes, a rate can imply duration when expressed as total volume / duration (e.g. 500mL/2 hours implies a duration of 2 hours). However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period.

                                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                312. MedicationRequest.dosageInstruction:posology.timing.id
                                                                Definition

                                                                Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                                ShortUnique id for inter-element referencing
                                                                Control0..1
                                                                This element is affected by the following invariants: ele-1
                                                                Typeid
                                                                Is Modifierfalse
                                                                XML FormatIn the XML format, this property is represented as an attribute.
                                                                Summaryfalse
                                                                314. MedicationRequest.dosageInstruction:posology.timing.extension
                                                                Definition

                                                                May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                                ShortAdditional content defined by implementations
                                                                Comments

                                                                There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                Control0..*
                                                                TypeExtension
                                                                Is Modifierfalse
                                                                Summaryfalse
                                                                Alternate Namesextensions, user content
                                                                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction.timing.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                                • value @ url
                                                                • 316. MedicationRequest.dosageInstruction:posology.timing.modifierExtension
                                                                  Definition

                                                                  May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                                  Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                                  ShortExtensions that cannot be ignored even if unrecognized
                                                                  Comments

                                                                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                  Control0..*
                                                                  TypeExtension
                                                                  Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                                  Summarytrue
                                                                  Requirements

                                                                  Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                                  Alternate Namesextensions, user content, modifiers
                                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                  318. MedicationRequest.dosageInstruction:posology.timing.event
                                                                  Definition

                                                                  Identifies specific times when the event occurs.

                                                                  ShortWhen the event occurs
                                                                  Control0..*
                                                                  TypedateTime
                                                                  Is Modifierfalse
                                                                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                  Summarytrue
                                                                  Requirements

                                                                  In a Medication Administration Record, for instance, you need to take a general specification, and turn it into a precise specification.

                                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                  320. MedicationRequest.dosageInstruction:posology.timing.repeat
                                                                  Definition

                                                                  A set of rules that describe when the event is scheduled.

                                                                  ShortWhen the event is to occur
                                                                  Control0..1
                                                                  TypeElement
                                                                  Is Modifierfalse
                                                                  Summarytrue
                                                                  Requirements

                                                                  Many timing schedules are determined by regular repetitions.

                                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                  tim-1: if there's a duration, there needs to be duration units (duration.empty() or durationUnit.exists())
                                                                  tim-2: if there's a period, there needs to be period units (period.empty() or periodUnit.exists())
                                                                  tim-4: duration SHALL be a non-negative value (duration.exists() implies duration >= 0)
                                                                  tim-5: period SHALL be a non-negative value (period.exists() implies period >= 0)
                                                                  tim-6: If there's a periodMax, there must be a period (periodMax.empty() or period.exists())
                                                                  tim-7: If there's a durationMax, there must be a duration (durationMax.empty() or duration.exists())
                                                                  tim-8: If there's a countMax, there must be a count (countMax.empty() or count.exists())
                                                                  tim-9: If there's an offset, there must be a when (and not C, CM, CD, CV) (offset.empty() or (when.exists() and when.select($this in ('C' | 'CM' | 'CD' | 'CV')).allFalse()))
                                                                  tim-10: If there's a timeOfDay, there cannot be a when, or vice versa (timeOfDay.empty() or when.empty())
                                                                  322. MedicationRequest.dosageInstruction:posology.timing.repeat.id
                                                                  Definition

                                                                  Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                                  ShortUnique id for inter-element referencing
                                                                  Control0..1
                                                                  This element is affected by the following invariants: ele-1
                                                                  Typestring
                                                                  Is Modifierfalse
                                                                  XML FormatIn the XML format, this property is represented as an attribute.
                                                                  Summaryfalse
                                                                  324. MedicationRequest.dosageInstruction:posology.timing.repeat.extension
                                                                  Definition

                                                                  May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                                  ShortAdditional content defined by implementations
                                                                  Comments

                                                                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                  Control0..*
                                                                  TypeExtension
                                                                  Is Modifierfalse
                                                                  Summaryfalse
                                                                  Alternate Namesextensions, user content
                                                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                  SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction.timing.repeat.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                                  • value @ url
                                                                  • 326. MedicationRequest.dosageInstruction:posology.timing.repeat.bounds[x]
                                                                    Definition

                                                                    Either a duration for the length of the timing schedule, a range of possible length, or outer bounds for start and/or end limits of the timing schedule.

                                                                    ShortLength/Range of lengths, or (Start and/or end) limits
                                                                    Control0..1
                                                                    TypeChoice of: Duration, Range, Period
                                                                    [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                                    Is Modifierfalse
                                                                    Summarytrue
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    328. MedicationRequest.dosageInstruction:posology.timing.repeat.count
                                                                    Definition

                                                                    A total count of the desired number of repetitions across the duration of the entire timing specification. If countMax is present, this element indicates the lower bound of the allowed range of count values.

                                                                    ShortNumber of times to repeat
                                                                    Comments

                                                                    If you have both bounds and count, then this should be understood as within the bounds period, until count times happens.

                                                                    Control0..1
                                                                    This element is affected by the following invariants: tim-8
                                                                    TypepositiveInt
                                                                    Is Modifierfalse
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Summarytrue
                                                                    Requirements

                                                                    Repetitions may be limited by end time or total occurrences.

                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    330. MedicationRequest.dosageInstruction:posology.timing.repeat.countMax
                                                                    Definition

                                                                    If present, indicates that the count is a range - so to perform the action between [count] and [countMax] times.

                                                                    ShortMaximum number of times to repeat
                                                                    Control0..1
                                                                    This element is affected by the following invariants: tim-8
                                                                    TypepositiveInt
                                                                    Is Modifierfalse
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Summarytrue
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    332. MedicationRequest.dosageInstruction:posology.timing.repeat.duration
                                                                    Definition

                                                                    How long this thing happens for when it happens. If durationMax is present, this element indicates the lower bound of the allowed range of the duration.

                                                                    ShortDuration of administration
                                                                    Comments

                                                                    For some events the duration is part of the definition of the event (e.g. IV infusions, where the duration is implicit in the specified quantity and rate). For others, it's part of the timing specification (e.g. exercise).

                                                                    Control0..1
                                                                    This element is affected by the following invariants: tim-7, tim-1, tim-4
                                                                    Typedecimal
                                                                    Is Modifierfalse
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Summarytrue
                                                                    Requirements

                                                                    Some activities are not instantaneous and need to be maintained for a period of time.

                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    334. MedicationRequest.dosageInstruction:posology.timing.repeat.durationMax
                                                                    Definition

                                                                    If present, indicates that the duration is a range - so to perform the action between [duration] and [durationMax] time length.

                                                                    ShortHow long when it happens (Max)
                                                                    Comments

                                                                    For some events the duration is part of the definition of the event (e.g. IV infusions, where the duration is implicit in the specified quantity and rate). For others, it's part of the timing specification (e.g. exercise).

                                                                    Control0..1
                                                                    This element is affected by the following invariants: tim-7
                                                                    Typedecimal
                                                                    Is Modifierfalse
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Summarytrue
                                                                    Requirements

                                                                    Some activities are not instantaneous and need to be maintained for a period of time.

                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    336. MedicationRequest.dosageInstruction:posology.timing.repeat.durationUnit
                                                                    Definition

                                                                    The units of time for the duration, in UCUM units Normal practice is to use the 'mo' code as a calendar month when calculating the next occurrence.

                                                                    Shorts | min | h | d | wk | mo | a - unit of time (UCUM)
                                                                    Control0..1
                                                                    This element is affected by the following invariants: tim-1
                                                                    BindingThe codes SHALL be taken from UnitsOfTime
                                                                    (required to http://hl7.org/fhir/ValueSet/units-of-time|5.0.0)

                                                                    A unit of time (units from UCUM).

                                                                    Typecode
                                                                    Is Modifierfalse
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Summarytrue
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    338. MedicationRequest.dosageInstruction:posology.timing.repeat.frequency
                                                                    Definition

                                                                    The number of times to repeat the action within the specified period. If frequencyMax is present, this element indicates the lower bound of the allowed range of the frequency.

                                                                    ShortIndicates the recurrence of the dosage. By default, every day
                                                                    Control0..1
                                                                    TypepositiveInt
                                                                    Is Modifierfalse
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Summarytrue
                                                                    Meaning if MissingIf no frequency is stated, the assumption is that the event occurs once per period, but systems SHOULD always be specific about this
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    340. MedicationRequest.dosageInstruction:posology.timing.repeat.frequencyMax
                                                                    Definition

                                                                    If present, indicates that the frequency is a range - so to repeat between [frequency] and [frequencyMax] times within the period or period range.

                                                                    ShortEvent occurs up to frequencyMax times per period
                                                                    Control0..1
                                                                    TypepositiveInt
                                                                    Is Modifierfalse
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Summarytrue
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    342. MedicationRequest.dosageInstruction:posology.timing.repeat.period
                                                                    Definition

                                                                    Indicates the duration of time over which repetitions are to occur; e.g. to express "3 times per day", 3 would be the frequency and "1 day" would be the period. If periodMax is present, this element indicates the lower bound of the allowed range of the period length.

                                                                    ShortThe duration to which the frequency applies. I.e. Event occurs frequency times per period
                                                                    Control0..1
                                                                    This element is affected by the following invariants: tim-6, tim-5, tim-2
                                                                    Typedecimal
                                                                    Is Modifierfalse
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Summarytrue
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    344. MedicationRequest.dosageInstruction:posology.timing.repeat.periodMax
                                                                    Definition

                                                                    If present, indicates that the period is a range from [period] to [periodMax], allowing expressing concepts such as "do this once every 3-5 days.

                                                                    ShortUpper limit of period (3-4 hours)
                                                                    Control0..1
                                                                    This element is affected by the following invariants: tim-6
                                                                    Typedecimal
                                                                    Is Modifierfalse
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Summarytrue
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    346. MedicationRequest.dosageInstruction:posology.timing.repeat.periodUnit
                                                                    Definition

                                                                    The units of time for the period in UCUM units Normal practice is to use the 'mo' code as a calendar month when calculating the next occurrence.

                                                                    Shorts | min | h | d | wk | mo | a - unit of time (UCUM)
                                                                    Control0..1
                                                                    This element is affected by the following invariants: tim-2
                                                                    BindingThe codes SHALL be taken from UnitsOfTime
                                                                    (required to http://hl7.org/fhir/ValueSet/units-of-time|5.0.0)

                                                                    A unit of time (units from UCUM).

                                                                    Typecode
                                                                    Is Modifierfalse
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Summarytrue
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    348. MedicationRequest.dosageInstruction:posology.timing.repeat.dayOfWeek
                                                                    Definition

                                                                    If one or more days of week is provided, then the action happens only on the specified day(s).

                                                                    Shortmon | tue | wed | thu | fri | sat | sun
                                                                    Comments

                                                                    If no days are specified, the action is assumed to happen every day as otherwise specified.

                                                                    Control0..*
                                                                    BindingThe codes SHALL be taken from DaysOfWeek
                                                                    (required to http://hl7.org/fhir/ValueSet/days-of-week|5.0.0)
                                                                    Typecode
                                                                    Is Modifierfalse
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Summarytrue
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    350. MedicationRequest.dosageInstruction:posology.timing.repeat.timeOfDay
                                                                    Definition

                                                                    Specified time of day for action to take place.

                                                                    ShortTime of day for action
                                                                    Comments

                                                                    When time of day is specified, it is inferred that the action happens every day (as filtered by dayofWeek) on the specified times. If there's a timeOfDay, there cannot be a when, or vice versa.

                                                                    Control0..*
                                                                    This element is affected by the following invariants: tim-10
                                                                    Typetime
                                                                    Is Modifierfalse
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Summarytrue
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    352. MedicationRequest.dosageInstruction:posology.timing.repeat.when
                                                                    Definition

                                                                    An approximate time period during the day, potentially linked to an event of daily living that indicates when the action should occur.

                                                                    ShortCode for time period of occurrence
                                                                    Comments

                                                                    When more than one event is listed, the event is tied to the union of the specified events.

                                                                    Control0..*
                                                                    This element is affected by the following invariants: tim-9, tim-10
                                                                    BindingThe codes SHALL be taken from EventTiming
                                                                    (required to http://hl7.org/fhir/ValueSet/event-timing|5.0.0)

                                                                    Real-world event relating to the schedule.

                                                                    Typecode
                                                                    Is Modifierfalse
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Summarytrue
                                                                    Requirements

                                                                    Timings are frequently determined by occurrences such as waking, eating and sleep.

                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    354. MedicationRequest.dosageInstruction:posology.timing.repeat.offset
                                                                    Definition

                                                                    The number of minutes from the event. If the event code does not indicate whether the minutes is before or after the event, then the offset is assumed to be after the event.

                                                                    ShortMinutes from event (before or after)
                                                                    Control0..1
                                                                    This element is affected by the following invariants: tim-9
                                                                    TypeunsignedInt
                                                                    Is Modifierfalse
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Summarytrue
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    356. MedicationRequest.dosageInstruction:posology.timing.code
                                                                    Definition

                                                                    A code for the timing schedule (or just text in code.text). Some codes such as BID are ubiquitous, but many institutions define their own additional codes. If a code is provided, the code is understood to be a complete statement of whatever is specified in the structured timing data, and either the code or the data may be used to interpret the Timing, with the exception that .repeat.bounds still applies over the code (and is not contained in the code).

                                                                    ShortC | BID | TID | QID | AM | PM | QD | QOD | +
                                                                    Comments

                                                                    BID etc. are defined as 'at institutionally specified times'. For example, an institution may choose that BID is "always at 7am and 6pm". If it is inappropriate for this choice to be made, the code BID should not be used. Instead, a distinct organization-specific code should be used in place of the HL7-defined BID code and/or a structured representation should be used (in this case, specifying the two event times).

                                                                    Control0..1
                                                                    BindingThe codes SHOULD be taken from TimingAbbreviation
                                                                    (preferred to http://hl7.org/fhir/ValueSet/timing-abbreviation)

                                                                    Code for a known / defined timing pattern.

                                                                    TypeCodeableConcept
                                                                    Is Modifierfalse
                                                                    Summarytrue
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    358. MedicationRequest.dosageInstruction:posology.asNeeded
                                                                    Definition

                                                                    Indicates whether the Medication is only taken when needed within a specific dosing schedule (Boolean option).

                                                                    ShortTake "as needed"
                                                                    Comments

                                                                    Can express "as needed" without a reason by setting the Boolean = True. In this case the CodeableConcept is not populated.

                                                                    Control0..1
                                                                    This element is affected by the following invariants: dos-1
                                                                    Typeboolean
                                                                    Is Modifierfalse
                                                                    Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                    Summarytrue
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    360. MedicationRequest.dosageInstruction:posology.asNeededFor
                                                                    Definition

                                                                    Indicates whether the Medication is only taken based on a precondition for taking the Medication (CodeableConcept).

                                                                    ShortTake "as needed" (for x)
                                                                    Comments

                                                                    Can express "as needed" with a reason by including the CodeableConcept. In this case the Boolean is assumed to be False, then the dose is given according to the schedule and is not "prn" or "as needed".

                                                                    Control0..*
                                                                    This element is affected by the following invariants: dos-1
                                                                    BindingFor example codes, see SNOMEDCTMedicationAsNeededReasonCodes
                                                                    (example to http://hl7.org/fhir/ValueSet/medication-as-needed-reason)

                                                                    A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc.

                                                                    TypeCodeableConcept
                                                                    Is Modifierfalse
                                                                    Summarytrue
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    362. MedicationRequest.dosageInstruction:posology.site
                                                                    Definition

                                                                    Body site to administer to.

                                                                    ShortBody site to administer to
                                                                    Comments

                                                                    If the use case requires attributes from the BodySite resource (e.g. to identify and track separately) then use the standard extension http://hl7.org/fhir/StructureDefinition/bodySite. May be a summary code, or a reference to a very precise definition of the location, or both.

                                                                    Control0..1
                                                                    BindingFor example codes, see SNOMEDCTAnatomicalStructureAdministrationSites
                                                                    (example to http://hl7.org/fhir/ValueSet/approach-site-codes)

                                                                    A coded concept describing the site location the medicine enters into or onto the body.

                                                                    TypeCodeableConcept
                                                                    Is Modifierfalse
                                                                    Summarytrue
                                                                    Requirements

                                                                    A coded specification of the anatomic site where the medication first enters the body.

                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    364. MedicationRequest.dosageInstruction:posology.route
                                                                    Definition

                                                                    How drug should enter body.

                                                                    ShortHow drug should enter body
                                                                    Control0..1
                                                                    BindingFor example codes, see SNOMEDCTRouteCodes
                                                                    (example to http://hl7.org/fhir/ValueSet/route-codes)

                                                                    A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.

                                                                    TypeCodeableConcept
                                                                    Is Modifierfalse
                                                                    Summarytrue
                                                                    Requirements

                                                                    A code specifying the route or physiological path of administration of a therapeutic agent into or onto a patient's body.

                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    366. MedicationRequest.dosageInstruction:posology.method
                                                                    Definition

                                                                    Technique for administering medication.

                                                                    ShortTechnique for administering medication
                                                                    Comments

                                                                    Terminologies used often pre-coordinate this term with the route and or form of administration.

                                                                    Control0..1
                                                                    BindingFor example codes, see SNOMEDCTAdministrationMethodCodes
                                                                    (example to http://hl7.org/fhir/ValueSet/administration-method-codes)

                                                                    A coded concept describing the technique by which the medicine is administered.

                                                                    TypeCodeableConcept
                                                                    Is Modifierfalse
                                                                    Summarytrue
                                                                    Requirements

                                                                    A coded value indicating the method by which the medication is introduced into or onto the body. Most commonly used for injections. For examples, Slow Push; Deep IV.

                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    368. MedicationRequest.dosageInstruction:posology.doseAndRate
                                                                    Definition

                                                                    Depending on the resource,this is the amount of medication administered, to be administered or typical amount to be administered.

                                                                    ShortAmount of medication administered, to be administered or typical amount to be administered
                                                                    Control0..*
                                                                    TypeElement
                                                                    Is Modifierfalse
                                                                    Summarytrue
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    370. MedicationRequest.dosageInstruction:posology.doseAndRate.id
                                                                    Definition

                                                                    Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                                    ShortUnique id for inter-element referencing
                                                                    Control0..1
                                                                    This element is affected by the following invariants: ele-1
                                                                    Typestring
                                                                    Is Modifierfalse
                                                                    XML FormatIn the XML format, this property is represented as an attribute.
                                                                    Summaryfalse
                                                                    372. MedicationRequest.dosageInstruction:posology.doseAndRate.extension
                                                                    Definition

                                                                    May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                                    ShortAdditional content defined by implementations
                                                                    Comments

                                                                    There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                    Control0..*
                                                                    TypeExtension
                                                                    Is Modifierfalse
                                                                    Summaryfalse
                                                                    Alternate Namesextensions, user content
                                                                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                    ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                    SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction.doseAndRate.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                                    • value @ url
                                                                    • 374. MedicationRequest.dosageInstruction:posology.doseAndRate.type
                                                                      Definition

                                                                      The kind of dose or rate specified, for example, ordered or calculated.

                                                                      ShortThe kind of dose or rate specified
                                                                      Control0..1
                                                                      BindingFor example codes, see DoseAndRateType
                                                                      (example to http://terminology.hl7.org/ValueSet/dose-rate-type)

                                                                      The kind of dose or rate specified.

                                                                      TypeCodeableConcept
                                                                      Is Modifierfalse
                                                                      Summarytrue
                                                                      Requirements

                                                                      If the type is not populated, assume to be "ordered".

                                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                      376. MedicationRequest.dosageInstruction:posology.doseAndRate.dose[x]
                                                                      Definition

                                                                      Amount of medication per dose.

                                                                      ShortAmount of medication per dose
                                                                      Comments

                                                                      Note that this specifies the quantity of the specified medication, not the quantity for each active ingredient(s). Each ingredient amount can be communicated in the Medication resource. For example, if one wants to communicate that a tablet was 375 mg, where the dose was one tablet, you can use the Medication resource to document that the tablet was comprised of 375 mg of drug XYZ. Alternatively if the dose was 375 mg, then you may only need to use the Medication resource to indicate this was a tablet. If the example were an IV such as dopamine and you wanted to communicate that 400mg of dopamine was mixed in 500 ml of some IV solution, then this would all be communicated in the Medication resource. If the administration is not intended to be instantaneous (rate is present or timing has a duration), this can be specified to convey the total amount to be administered over the period of time as indicated by the schedule e.g. 500 ml in dose, with timing used to convey that this should be done over 4 hours.

                                                                      Control0..1
                                                                      TypeChoice of: Range, Quantity(SimpleQuantity)
                                                                      [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                                      Is Modifierfalse
                                                                      Summarytrue
                                                                      Requirements

                                                                      The amount of therapeutic or other substance given at one administration event.

                                                                      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                      SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction.doseAndRate.dose[x]. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                                      • type @ $this
                                                                      • 378. MedicationRequest.dosageInstruction:posology.doseAndRate.dose[x]:doseQuantity
                                                                        Slice NamedoseQuantity
                                                                        Definition

                                                                        Amount of medication per dose.

                                                                        ShortQuantity of the prescription element in the dosage
                                                                        Comments

                                                                        Note that this specifies the quantity of the specified medication, not the quantity for each active ingredient(s). Each ingredient amount can be communicated in the Medication resource. For example, if one wants to communicate that a tablet was 375 mg, where the dose was one tablet, you can use the Medication resource to document that the tablet was comprised of 375 mg of drug XYZ. Alternatively if the dose was 375 mg, then you may only need to use the Medication resource to indicate this was a tablet. If the example were an IV such as dopamine and you wanted to communicate that 400mg of dopamine was mixed in 500 ml of some IV solution, then this would all be communicated in the Medication resource. If the administration is not intended to be instantaneous (rate is present or timing has a duration), this can be specified to convey the total amount to be administered over the period of time as indicated by the schedule e.g. 500 ml in dose, with timing used to convey that this should be done over 4 hours.

                                                                        Control0..1
                                                                        TypeQuantity(SimpleQuantity)
                                                                        [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                                        Is Modifierfalse
                                                                        Summarytrue
                                                                        Requirements

                                                                        The amount of therapeutic or other substance given at one administration event.

                                                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                        380. MedicationRequest.dosageInstruction:posology.doseAndRate.rate[x]
                                                                        Definition

                                                                        Amount of medication per unit of time.

                                                                        ShortAmount of medication per unit of time
                                                                        Comments

                                                                        It is possible to supply both a rate and a doseQuantity to provide full details about how the medication is to be administered and supplied. If the rate is intended to change over time, depending on local rules/regulations, each change should be captured as a new version of the MedicationRequest with an updated rate, or captured with a new MedicationRequest with the new rate.

                                                                        It is possible to specify a rate over time (for example, 100 ml/hour) using either the rateRatio and rateQuantity. The rateQuantity approach requires systems to have the capability to parse UCUM grammar where ml/hour is included rather than a specific ratio where the time is specified as the denominator. Where a rate such as 500ml over 2 hours is specified, the use of rateRatio may be more semantically correct than specifying using a rateQuantity of 250 mg/hour.

                                                                        Control0..1
                                                                        TypeChoice of: Ratio, Range, Quantity(SimpleQuantity)
                                                                        [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                                        Is Modifierfalse
                                                                        Summarytrue
                                                                        Requirements

                                                                        Identifies the speed with which the medication was or will be introduced into the patient. Typically the rate for an infusion e.g. 100 ml per 1 hour or 100 ml/hr. May also be expressed as a rate per unit of time e.g. 500 ml per 2 hours. Other examples: 200 mcg/min or 200 mcg/1 minute; 1 liter/8 hours. Sometimes, a rate can imply duration when expressed as total volume / duration (e.g. 500mL/2 hours implies a duration of 2 hours). However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period.

                                                                        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                        SlicingThis element introduces a set of slices on MedicationRequest.dosageInstruction.doseAndRate.rate[x]. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                                                        • type @ $this
                                                                        • 382. MedicationRequest.dosageInstruction:posology.doseAndRate.rate[x]:rateQuantity
                                                                          Slice NamerateQuantity
                                                                          Definition

                                                                          Amount of medication per unit of time.

                                                                          ShortRate of administration in the case of injection
                                                                          Comments

                                                                          It is possible to supply both a rate and a doseQuantity to provide full details about how the medication is to be administered and supplied. If the rate is intended to change over time, depending on local rules/regulations, each change should be captured as a new version of the MedicationRequest with an updated rate, or captured with a new MedicationRequest with the new rate.

                                                                          It is possible to specify a rate over time (for example, 100 ml/hour) using either the rateRatio and rateQuantity. The rateQuantity approach requires systems to have the capability to parse UCUM grammar where ml/hour is included rather than a specific ratio where the time is specified as the denominator. Where a rate such as 500ml over 2 hours is specified, the use of rateRatio may be more semantically correct than specifying using a rateQuantity of 250 mg/hour.

                                                                          Control0..1
                                                                          TypeQuantity(SimpleQuantity)
                                                                          [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                                          Is Modifierfalse
                                                                          Summarytrue
                                                                          Requirements

                                                                          Identifies the speed with which the medication was or will be introduced into the patient. Typically the rate for an infusion e.g. 100 ml per 1 hour or 100 ml/hr. May also be expressed as a rate per unit of time e.g. 500 ml per 2 hours. Other examples: 200 mcg/min or 200 mcg/1 minute; 1 liter/8 hours. Sometimes, a rate can imply duration when expressed as total volume / duration (e.g. 500mL/2 hours implies a duration of 2 hours). However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period.

                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          384. MedicationRequest.dosageInstruction:posology.maxDosePerPeriod
                                                                          Definition

                                                                          Upper limit on medication per unit of time.

                                                                          ShortUpper limit on medication per unit of time
                                                                          Comments

                                                                          This is intended for use as an adjunct to the dosage when there is an upper cap. For example "2 tablets every 4 hours to a maximum of 8/day".

                                                                          Control0..*
                                                                          TypeRatio
                                                                          Is Modifierfalse
                                                                          Summarytrue
                                                                          Requirements

                                                                          The maximum total quantity of a therapeutic substance that may be administered to a subject over the period of time. For example, 1000mg in 24 hours.

                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          386. MedicationRequest.dosageInstruction:posology.maxDosePerAdministration
                                                                          Definition

                                                                          Upper limit on medication per administration.

                                                                          ShortUpper limit on medication per administration
                                                                          Comments

                                                                          This is intended for use as an adjunct to the dosage when there is an upper cap. For example, a body surface area related dose with a maximum amount, such as 1.5 mg/m2 (maximum 2 mg) IV over 5 – 10 minutes would have doseQuantity of 1.5 mg/m2 and maxDosePerAdministration of 2 mg.

                                                                          Control0..1
                                                                          TypeQuantity(SimpleQuantity)
                                                                          Is Modifierfalse
                                                                          Summarytrue
                                                                          Requirements

                                                                          The maximum total quantity of a therapeutic substance that may be administered to a subject per administration.

                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          388. MedicationRequest.dosageInstruction:posology.maxDosePerLifetime
                                                                          Definition

                                                                          Upper limit on medication per lifetime of the patient.

                                                                          ShortUpper limit on medication per lifetime of the patient
                                                                          Control0..1
                                                                          TypeQuantity(SimpleQuantity)
                                                                          Is Modifierfalse
                                                                          Summarytrue
                                                                          Requirements

                                                                          The maximum total quantity of a therapeutic substance that may be administered per lifetime of the subject.

                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          390. MedicationRequest.dispenseRequest
                                                                          Definition

                                                                          Indicates the specific details for the dispense or medication supply part of a medication request (also known as a Medication Prescription or Medication Order). Note that this information is not always sent with the order. There may be in some settings (e.g. hospitals) institutional or system support for completing the dispense details in the pharmacy department.

                                                                          ShortMedication supply authorization
                                                                          Control0..1
                                                                          TypeBackboneElement
                                                                          Is Modifierfalse
                                                                          Must Supportfalse
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          392. MedicationRequest.dispenseRequest.id
                                                                          Definition

                                                                          Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                                          ShortUnique id for inter-element referencing
                                                                          Control0..1
                                                                          This element is affected by the following invariants: ele-1
                                                                          Typestring
                                                                          Is Modifierfalse
                                                                          XML FormatIn the XML format, this property is represented as an attribute.
                                                                          Summaryfalse
                                                                          394. MedicationRequest.dispenseRequest.extension
                                                                          Definition

                                                                          May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                                          ShortAdditional content defined by implementations
                                                                          Comments

                                                                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                          Control0..*
                                                                          TypeExtension
                                                                          Is Modifierfalse
                                                                          Summaryfalse
                                                                          Alternate Namesextensions, user content
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                          396. MedicationRequest.dispenseRequest.modifierExtension
                                                                          Definition

                                                                          May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                                          Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                                          ShortExtensions that cannot be ignored even if unrecognized
                                                                          Comments

                                                                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                          Control0..*
                                                                          TypeExtension
                                                                          Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                                          Summarytrue
                                                                          Requirements

                                                                          Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                                          Alternate Namesextensions, user content, modifiers
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                          398. MedicationRequest.dispenseRequest.initialFill
                                                                          Definition

                                                                          Indicates the quantity or duration for the first dispense of the medication.

                                                                          ShortFirst fill details
                                                                          Comments

                                                                          If populating this element, either the quantity or the duration must be included.

                                                                          Control0..1
                                                                          TypeBackboneElement
                                                                          Is Modifierfalse
                                                                          Must Supportfalse
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          400. MedicationRequest.dispenseRequest.initialFill.id
                                                                          Definition

                                                                          Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                                          ShortUnique id for inter-element referencing
                                                                          Control0..1
                                                                          This element is affected by the following invariants: ele-1
                                                                          Typestring
                                                                          Is Modifierfalse
                                                                          XML FormatIn the XML format, this property is represented as an attribute.
                                                                          Summaryfalse
                                                                          402. MedicationRequest.dispenseRequest.initialFill.extension
                                                                          Definition

                                                                          May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                                          ShortAdditional content defined by implementations
                                                                          Comments

                                                                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                          Control0..*
                                                                          TypeExtension
                                                                          Is Modifierfalse
                                                                          Summaryfalse
                                                                          Alternate Namesextensions, user content
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                          404. MedicationRequest.dispenseRequest.initialFill.modifierExtension
                                                                          Definition

                                                                          May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                                          Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                                          ShortExtensions that cannot be ignored even if unrecognized
                                                                          Comments

                                                                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                          Control0..*
                                                                          TypeExtension
                                                                          Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                                          Summarytrue
                                                                          Requirements

                                                                          Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                                          Alternate Namesextensions, user content, modifiers
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                          406. MedicationRequest.dispenseRequest.initialFill.quantity
                                                                          Definition

                                                                          The amount or quantity to provide as part of the first dispense.

                                                                          ShortFirst fill quantity
                                                                          Control0..1
                                                                          TypeQuantity(SimpleQuantity)
                                                                          Is Modifierfalse
                                                                          Must Supportfalse
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          408. MedicationRequest.dispenseRequest.initialFill.duration
                                                                          Definition

                                                                          The length of time that the first dispense is expected to last.

                                                                          ShortFirst fill duration
                                                                          Control0..1
                                                                          TypeDuration
                                                                          Is Modifierfalse
                                                                          Must Supportfalse
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          410. MedicationRequest.dispenseRequest.dispenseInterval
                                                                          Definition

                                                                          The minimum period of time that must occur between dispenses of the medication.

                                                                          ShortMinimum period of time between dispenses
                                                                          Control0..1
                                                                          TypeDuration
                                                                          Is Modifierfalse
                                                                          Must Supportfalse
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          412. MedicationRequest.dispenseRequest.validityPeriod
                                                                          Definition

                                                                          This indicates the validity period of a prescription (stale dating the Prescription).

                                                                          ShortTime period supply is authorized for
                                                                          Comments

                                                                          It reflects the prescribers' perspective for the validity of the prescription. Dispenses must not be made against the prescription outside of this period. The lower-bound of the Dispensing Window signifies the earliest date that the prescription can be filled for the first time. If an upper-bound is not specified then the Prescription is open-ended or will default to a stale-date based on regulations.

                                                                          Control0..1
                                                                          TypePeriod
                                                                          Is Modifierfalse
                                                                          Must Supportfalse
                                                                          Summaryfalse
                                                                          Requirements

                                                                          Indicates when the Prescription becomes valid, and when it ceases to be a dispensable Prescription.

                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          414. MedicationRequest.dispenseRequest.numberOfRepeatsAllowed
                                                                          Definition

                                                                          An integer indicating the number of times, in addition to the original dispense, (aka refills or repeats) that the patient can receive the prescribed medication. Usage Notes: This integer does not include the original order dispense. This means that if an order indicates dispense 30 tablets plus "3 repeats", then the order can be dispensed a total of 4 times and the patient can receive a total of 120 tablets. A prescriber may explicitly say that zero refills are permitted after the initial dispense.

                                                                          ShortNumber of refills authorized
                                                                          Comments

                                                                          If displaying "number of authorized fills", add 1 to this number.

                                                                          Control0..1
                                                                          TypeunsignedInt
                                                                          Is Modifierfalse
                                                                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                          Must Supportfalse
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          416. MedicationRequest.dispenseRequest.quantity
                                                                          Definition

                                                                          The amount that is to be dispensed for one fill.

                                                                          ShortAmount of medication to supply per dispense
                                                                          Control0..1
                                                                          TypeQuantity(SimpleQuantity)
                                                                          Is Modifierfalse
                                                                          Must Supportfalse
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          418. MedicationRequest.dispenseRequest.expectedSupplyDuration
                                                                          Definition

                                                                          Identifies the period time over which the supplied product is expected to be used, or the length of time the dispense is expected to last.

                                                                          ShortNumber of days supply per dispense
                                                                          Comments

                                                                          In some situations, this attribute may be used instead of quantity to identify the amount supplied by how long it is expected to last, rather than the physical quantity issued, e.g. 90 days supply of medication (based on an ordered dosage). When possible, it is always better to specify quantity, as this tends to be more precise. expectedSupplyDuration will always be an estimate that can be influenced by external factors.

                                                                          Control0..1
                                                                          TypeDuration
                                                                          Is Modifierfalse
                                                                          Must Supportfalse
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          420. MedicationRequest.dispenseRequest.dispenser
                                                                          Definition

                                                                          Indicates the intended performing Organization that will dispense the medication as specified by the prescriber.

                                                                          ShortIntended performer of dispense
                                                                          Control0..1
                                                                          TypeReference(Organization)
                                                                          Is Modifierfalse
                                                                          Must Supportfalse
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          422. MedicationRequest.dispenseRequest.dispenserInstruction
                                                                          Definition

                                                                          Provides additional information to the dispenser, for example, counselling to be provided to the patient.

                                                                          ShortAdditional information for the dispenser
                                                                          Control0..*
                                                                          TypeAnnotation
                                                                          Is Modifierfalse
                                                                          Must Supportfalse
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          424. MedicationRequest.dispenseRequest.doseAdministrationAid
                                                                          Definition

                                                                          Provides information about the type of adherence packaging to be supplied for the medication dispense.

                                                                          ShortType of adherence packaging to use for the dispense
                                                                          Control0..1
                                                                          BindingFor example codes, see MedicationDoseAids
                                                                          (example to http://hl7.org/fhir/ValueSet/medication-dose-aid)
                                                                          TypeCodeableConcept
                                                                          Is Modifierfalse
                                                                          Must Supportfalse
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          426. MedicationRequest.substitution
                                                                          Definition

                                                                          Indicates whether or not substitution can or should be part of the dispense. In some cases, substitution must happen, in other cases substitution must not happen. This block explains the prescriber's intent. If nothing is specified substitution may be done.

                                                                          ShortCharacterises a prescription item added by the pharmacist, either as a proposed replacement or as a suggestion
                                                                          Control0..1
                                                                          TypeBackboneElement
                                                                          Is Modifierfalse
                                                                          Must Supporttrue
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          428. MedicationRequest.substitution.id
                                                                          Definition

                                                                          Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                                                          ShortUnique id for inter-element referencing
                                                                          Control0..1
                                                                          This element is affected by the following invariants: ele-1
                                                                          Typestring
                                                                          Is Modifierfalse
                                                                          XML FormatIn the XML format, this property is represented as an attribute.
                                                                          Summaryfalse
                                                                          430. MedicationRequest.substitution.extension
                                                                          Definition

                                                                          May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                                                          ShortAdditional content defined by implementations
                                                                          Comments

                                                                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                          Control0..*
                                                                          TypeExtension
                                                                          Is Modifierfalse
                                                                          Summaryfalse
                                                                          Alternate Namesextensions, user content
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                          432. MedicationRequest.substitution.modifierExtension
                                                                          Definition

                                                                          May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                                                          Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

                                                                          ShortExtensions that cannot be ignored even if unrecognized
                                                                          Comments

                                                                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                                                          Control0..*
                                                                          TypeExtension
                                                                          Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
                                                                          Summarytrue
                                                                          Requirements

                                                                          Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

                                                                          Alternate Namesextensions, user content, modifiers
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                                                          434. MedicationRequest.substitution.allowed[x]
                                                                          Definition

                                                                          True if the prescriber allows a different drug to be dispensed from what was prescribed.

                                                                          ShortWhether substitution is allowed or not
                                                                          Comments

                                                                          This element is labeled as a modifier because whether substitution is allow or not, it cannot be ignored.

                                                                          Control1..1
                                                                          BindingThe codes SHOULD be taken from ActSubstanceAdminSubstitutionCode
                                                                          (preferred to http://terminology.hl7.org/ValueSet/v3-ActSubstanceAdminSubstitutionCode)

                                                                          Identifies the type of substitution allowed.

                                                                          TypeChoice of: boolean, CodeableConcept
                                                                          [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                                                          Is Modifierfalse
                                                                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                                                          Must Supportfalse
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          436. MedicationRequest.substitution.reason
                                                                          Definition

                                                                          Indicates the reason for the substitution, or why substitution must or must not be performed.

                                                                          ShortWhy should (not) substitution be made
                                                                          Control0..1
                                                                          BindingFor example codes, see SubstanceAdminSubstitutionReason
                                                                          (example to http://terminology.hl7.org/ValueSet/v3-SubstanceAdminSubstitutionReason)

                                                                          SubstanceAdminSubstitutionReason

                                                                          TypeCodeableConcept
                                                                          Is Modifierfalse
                                                                          Must Supportfalse
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
                                                                          438. MedicationRequest.eventHistory
                                                                          Definition

                                                                          Links to Provenance records for past versions of this resource or fulfilling request or event resources that identify key state transitions or updates that are likely to be relevant to a user looking at the current version of the resource.

                                                                          ShortA list of events of interest in the lifecycle
                                                                          Comments

                                                                          This might not include provenances for all versions of the request – only those deemed "relevant" or important. This SHALL NOT include the provenance associated with this current version of the resource. (If that provenance is deemed to be a "relevant" change, it will need to be added as part of a later update. Until then, it can be queried directly as the provenance that points to this version using _revinclude All Provenances should have some historical version of this Request as their subject.).

                                                                          Control0..*
                                                                          TypeReference(Provenance)
                                                                          Is Modifierfalse
                                                                          Must Supportfalse
                                                                          Summaryfalse
                                                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))